MYO1F

Unconventional myosin-If · O00160 · MYO1F on Sugi Atlas →

440 patent compounds predicted against MYO1F, 383 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL4699731 SCHEMBL4699731 1.00 2/20
SCHEMBL16111548 SCHEMBL16111548 1.00 2/20
SCHEMBL29358745 SCHEMBL29358745 1.00 2/20
SCHEMBL29380618 SCHEMBL29380618 1.00 2/20
SCHEMBL29931136 SCHEMBL29931136 1.00 2/20
SCHEMBL4697866 SCHEMBL4697866 0.89 2/20
SCHEMBL24532075 SCHEMBL24532075 0.89 2/20
SCHEMBL4697696 SCHEMBL4697696 0.86 2/20
SCHEMBL23092285 SCHEMBL23092285 0.86 2/20
SCHEMBL29688472 SCHEMBL29688472 0.86 2/20
SCHEMBL22024695 SCHEMBL22024695 0.86 2/20
SCHEMBL16136600 SCHEMBL16136600 0.84 2/20
SCHEMBL24532058 SCHEMBL24532058 0.83 2/20
SCHEMBL4699947 SCHEMBL4699947 0.83 2/20
SCHEMBL22025026 SCHEMBL22025026 0.82 2/20
SCHEMBL22119546 SCHEMBL22119546 0.82 2/20
SCHEMBL24532062 SCHEMBL24532062 0.82 2/20
SCHEMBL18804561 SCHEMBL18804561 0.81 2/20
SCHEMBL22024561 SCHEMBL22024561 0.81 2/20
SCHEMBL22025030 SCHEMBL22025030 0.81 2/20

Clinical trials — most relevant to MYO1F by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Effect of Neuromuscular Electrical Stimulation (NMES) PHASE2COMPLETED
Evaluating MED2005 & Nitrostat Bioavailability PHASE1COMPLETED
Characteristics of Nondystrophic Myotonias nanCOMPLETED
Transcutaneous Functional Magnetic Muscle Stimulation in Critically Ill nanUNKNOWN
Chronic Muscle Disuse in the Elderly nanCOMPLETED
Hemodynamic Assessment of underLying myocyTe Function in Right Heart Failure nanRECRUITING
Genetic Testing in Primary Congenital Glaucoma Patients nanUNKNOWN
A Multicenter Phenotype-Genotype Analysis of LGMD Patients in China nanENROLLING_BY_INVITATION
Natural History Study for Patients With Nemaline Myopathy in Belgium nanNOT_YET_RECRUITING
Molecular and Genetic Studies of Congenital Myopathies nanRECRUITING
PITA-HF: Feasibility, Safety, and Tolerability nanCOMPLETED
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer nanUNKNOWN
3D-Microscopic Muscle Architecture in Cerebral Palsy nanRECRUITING
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease nanCOMPLETED
Effect of Exercise on the Human Skeletal Muscle Phosphoproteome nanCOMPLETED
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Signs and Symptoms Associated With Molecular Defects in Genetically Inherited Heart Disease nanCOMPLETED
Contractile Cross Sectional Areas and Muscle Strength in Patients With Congenital Myopathies nanCOMPLETED
Multispectral Optoacoustic Tomography for Advanced Imaging of Centronuclear Myopathy nanRECRUITING
WiTNNess - TNNT1 Myopathy Natural History Study nanRECRUITING
Registry of Unexplained Cardiac Arrest nanCOMPLETED
The Muscle in Cerebral Palsy; Sarcomere Length in Vivo and Microscopic Characterization of Biopsies. nanRECRUITING
Evaluation of Vasopressin in the Vessels of Ovarian Neoplasms nanCOMPLETED
Spinal Muscular Atrophy (SMA) Biomarkers Study in the Immediate Postnatal Period of Development nanCOMPLETED
Idiopathic Dilated Cardiomyopathy nanCOMPLETED
Genetic Basis of Non Syndromic Congenital Diaphragmatic Hernia nanCOMPLETED
The Prevalence of RYR1-related Disease nanNOT_YET_RECRUITING
Phenotypic and Genotypic Identification and Characterization of MYH9-related Constitutional Thrombocytopenia nanCOMPLETED
Skeletal Muscle Regeneration in Survivors of Critical Illness: How to Prevent Satellite Cell Failure? nanRECRUITING
Phenotype - Genotype Correlation in a Sample of Egyptian Patients With Congenital Myopathies and Congenital Muscular Dystrophies nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a MYO1F binder may also engage these)

ProteinNameSimilarity
P70248 0.999 P70248 →
E9Q634 0.995 E9Q634 →
Q9WTI7 0.993 Q9WTI7 →
Q12965 0.993 Q12965 →
Q27966 0.992 Q27966 →
Q63356 0.992 Q63356 →
Q6CVE9 0.990 Q6CVE9 →
A4RE77 0.989 A4RE77 →
Q92002 0.988 Q92002 →
P0CP00 0.988 P0CP00 →
A5DKH0 0.987 A5DKH0 →
O00159 0.987 O00159 →
Q6C7C0 0.987 Q6C7C0 →
A8PWF6 0.987 A8PWF6 →
Q99323 0.986 Q99323 →
Q758Q9 0.986 Q758Q9 →
P0CP01 0.986 P0CP01 →
P10568 0.986 P10568 →
A7TDZ8 0.985 A7TDZ8 →
A6SED8 0.985 A6SED8 →
Q63355 0.985 Q63355 →
O88329 0.985 O88329 →
A2AQP0 0.984 A2AQP0 →
Q9UBC5 0.984 Q9UBC5 →
P02565 0.984 P02565 →
Q5ZLA6 0.984 Q5ZLA6 →
Q6FMJ3 0.983 Q6FMJ3 →
Q29P71 0.983 Q29P71 →
A7EK16 0.983 A7EK16 →
P13542 0.983 P13542 →