Sugi Predict

Sugi Predict / Targets / PAFAH1B3

PAFAH1B3

Platelet-activating factor acetylhydrolase IB subunit alpha1 · Q15102 · PAFAH1B3 on Sugi Atlas →

0 patent compounds predicted against PAFAH1B3, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PAFAH1B3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The HDL Particle Protection Study PHASE4COMPLETED
Customized Choice of Oral P2Y12 Receptor Blocker PHASE4UNKNOWN
Determining Genetic Role in Treatment Response to Anti-Platelet Interventions (The PAPI Study) PHASE4COMPLETED
Pharmacogenomics of Antiplatelet Response - I PHASE4COMPLETED
The Effects of Tirofiban in Diabetic Patients Undergoing Elective Percutaneous Coronary Intervention PHASE4UNKNOWN
Use of In-Line Filtration in Critically Ill Children PHASE4COMPLETED
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides PHASE1COMPLETED
The Impact of Genotype on Pharmacokinetics and Antiplatelet Effects of Ticagrelor in Healthy Chinese PHASE1COMPLETED
Platelet-activating Factor Acetylhydrolase (Paf-ah) Gene Expression nanCOMPLETED
Physiopathology of Pulmonary Arterial Hypertension: Mechanistic Studies nanUNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Genetic Markers of CHD Risk in Men and Women nanCOMPLETED
Normal Donor Blood Draws for Platelet Studies and Biomarker Evaluation (ND-PLT) nanRECRUITING
Thrombin Regulated Platelet Activation nanCOMPLETED
Study of Polymorphisms in pear1 Gene Link to Platelet Activation and Signaling Pathway Variations nanWITHDRAWN
PLatelets Acetyl-CoA Carboxylase Phosphorylation State in SEPtic Shock nanCOMPLETED
CADASIL Disease Discovery nanCOMPLETED
Evaluation of a New Approach of the Diagnosis of Constitutional Functional Disorders of Platelets nanCOMPLETED
The Association Between Post-ERCP Acute Pancreatitis and Various Genetic Mutations nanCOMPLETED
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Study of Constitutional Platelet Disease nanUNKNOWN
the Role of plin5 in the Development of Nonalcoholic Fatty Liver Disease. nanUNKNOWN
Platelet Acetyl Coenzyme A Carboxylase Phosphorylation in Coronary Artery Disease nanCOMPLETED
Genetic Basis of Abdominal Aortic Aneurysm nanCOMPLETED
Platelet Hyperreactivity Project nanCOMPLETED
The MyoThrombus Study nanCOMPLETED
Diet Intervention and GEnetic STudy (DIGEST-Pilot) nanUNKNOWN
Genes Associated With Development of Pulmonary Arterial Hypertension in Patients With Congenital Shunt Lesions nanRECRUITING
Genetic Determinants of Kawasaki Disease nanUNKNOWN
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD) nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PAFAH1B3 binder may also engage these)

ProteinNameSimilarity
Q29460 — 1.000 Q29460 →
O35263 — 1.000 O35263 →
Q61205 — 1.000 Q61205 →
Q5R6X1 — 1.000 Q5R6X1 →
Q5ZMS2 — 0.992 Q5ZMS2 →
P68401 — 0.988 P68401 →
Q61206 — 0.987 Q61206 →
O35264 — 0.987 O35264 →
PAFAH1B2 Platelet-activating factor acetylhydrolase IB subunit alpha2 0.986 landscape →
Q9VXP4 — 0.968 Q9VXP4 →
Q8K370 — 0.967 Q8K370 →
P63890 — 0.965 P63890 →
B5FTS8 — 0.965 B5FTS8 →
B4T460 — 0.965 B4T460 →
P63889 — 0.965 P63889 →
Q2T9L8 — 0.965 Q2T9L8 →
Q57KJ1 — 0.965 Q57KJ1 →
B4I9N7 — 0.965 B4I9N7 →
P76092 — 0.965 P76092 →
Q5RCH4 — 0.964 Q5RCH4 →
Q2SHM4 — 0.964 Q2SHM4 →
P22570 — 0.964 P22570 →
O88428 — 0.964 O88428 →
Q3U3Q1 — 0.964 Q3U3Q1 →
B2VG00 — 0.964 B2VG00 →
Q91YL3 — 0.963 Q91YL3 →
Q8FEJ2 — 0.963 Q8FEJ2 →
Q8VCR7 — 0.963 Q8VCR7 →
A0A5F8AH41 — 0.963 A0A5F8AH41 →
Q32KX8 — 0.963 Q32KX8 →