PAFAH1B2

Platelet-activating factor acetylhydrolase IB subunit alpha2 · P68402 · PAFAH1B2 on Sugi Atlas →

242 patent compounds predicted against PAFAH1B2, 193 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Methoxyarachidonoyl Fluorophosphonate (SCHEMBL8253710)	1.00	1/20
Methoxyarachidonoyl Fluorophosphonate (SCHEMBL19877180)	1.00	1/20
Methoxyarachidonoyl Fluorophosphonate (SCHEMBL22222736)	1.00	1/20
SCHEMBL20971528	0.94	1/20
SCHEMBL23617058	0.79	1/20
SCHEMBL4271993	0.66	1/20
SCHEMBL4271998	0.66	1/20
SCHEMBL177496	0.63	1/20
SCHEMBL458863	0.63	1/20
SCHEMBL18437601	0.62	1/20
SCHEMBL1887711	0.61	1/20
SCHEMBL2184369	0.60	1/20
SCHEMBL2184370	0.60	1/20
SCHEMBL19602995	0.60	1/20
SCHEMBL22187698	0.60	1/20
SCHEMBL2783833	0.59	1/20
SCHEMBL20971526	0.59	1/20
SCHEMBL22187633	0.59	1/20
SCHEMBL22187634	0.59	1/20
SCHEMBL23198743	0.58	1/20

Clinical trials — most relevant to PAFAH1B2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Customized Choice of Oral P2Y12 Receptor Blocker	PHASE4	UNKNOWN
Determining Genetic Role in Treatment Response to Anti-Platelet Interventions (The PAPI Study)	PHASE4	COMPLETED
The Effects of Tirofiban in Diabetic Patients Undergoing Elective Percutaneous Coronary Intervention	PHASE4	UNKNOWN
Pharmacogenomics of Antiplatelet Response - I	PHASE4	COMPLETED
The HDL Particle Protection Study	PHASE4	COMPLETED
Aspirin and Renal Disease Progression in Patients With Type 2 Diabetes	PHASE3	UNKNOWN
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides	PHASE1	COMPLETED
Platelet-activating Factor Acetylhydrolase (Paf-ah) Gene Expression	nan	COMPLETED
Physiopathology of Pulmonary Arterial Hypertension: Mechanistic Studies	nan	UNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH)	nan	COMPLETED
PLatelets Acetyl-CoA Carboxylase Phosphorylation State in SEPtic Shock	nan	COMPLETED
Genetic Markers of CHD Risk in Men and Women	nan	COMPLETED
CADASIL Disease Discovery	nan	COMPLETED
Normal Donor Blood Draws for Platelet Studies and Biomarker Evaluation (ND-PLT)	nan	RECRUITING
Evaluation of a New Approach of the Diagnosis of Constitutional Functional Disorders of Platelets	nan	COMPLETED
Study of Polymorphisms in pear1 Gene Link to Platelet Activation and Signaling Pathway Variations	nan	WITHDRAWN
Platelet Acetyl Coenzyme A Carboxylase Phosphorylation in Coronary Artery Disease	nan	COMPLETED
Study of Constitutional Platelet Disease	nan	UNKNOWN
The MyoThrombus Study	nan	COMPLETED
Platelet Hyperreactivity Project	nan	COMPLETED
Genetic Basis of Abdominal Aortic Aneurysm	nan	COMPLETED
Genetic Analysis of Gray Platelet Syndrome	nan	COMPLETED
The Association Between Post-ERCP Acute Pancreatitis and Various Genetic Mutations	nan	COMPLETED
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD)	nan	COMPLETED
Thrombin Regulated Platelet Activation	nan	COMPLETED
Genes Associated With Development of Pulmonary Arterial Hypertension in Patients With Congenital Shunt Lesions	nan	RECRUITING
Genetic Determinants of Kawasaki Disease	nan	UNKNOWN
Cardioprotective Properties of ELAIOTSIPOURA	nan	COMPLETED
An Epidemiological Study of Subjects With Immune Thrombocytopenic Purpura to Evaluate the Relationship Between Platelet Counts, Endogenous Thrombopoietin Levels, Endogenous Anti-Thrombopoietin Antibodies, and Selected Autoimmune Markers	nan	COMPLETED
Diet Intervention and GEnetic STudy (DIGEST-Pilot)	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a PAFAH1B2 binder may also engage these)

Protein	Name	Similarity
Q5R4G2	—	1.000	Q5R4G2 →
O35264	—	1.000	O35264 →
P68401	—	1.000	P68401 →
Q61206	—	1.000	Q61206 →
Q5ZMS2	—	1.000	Q5ZMS2 →
Q61205	—	0.992	Q61205 →
O35263	—	0.992	O35263 →
Q29460	—	0.990	Q29460 →
PAFAH1B3	Platelet-activating factor acetylhydrolase IB subunit alpha1	0.990	landscape →
Q5R6X1	—	0.985	Q5R6X1 →
Q9VXP4	—	0.982	Q9VXP4 →
Q7XXR3	—	0.974	Q7XXR3 →
Q8VYX1	—	0.973	Q8VYX1 →
Q9SRM5	—	0.973	Q9SRM5 →
Q711G3	—	0.972	Q711G3 →
A0A1D6NER6	—	0.971	A0A1D6NER6 →
Q9C8J4	—	0.971	Q9C8J4 →
SMS	Spermine synthase	0.971	landscape →
Q95K79	—	0.971	Q95K79 →
P41734	—	0.970	P41734 →
B0BML1	—	0.970	B0BML1 →
P97355	—	0.970	P97355 →
Q5ZJM3	—	0.970	Q5ZJM3 →
Q944H0	—	0.970	Q944H0 →
Q5SNQ7	—	0.969	Q5SNQ7 →
Q96BT7	—	0.969	Q96BT7 →
Q9FR44	—	0.969	Q9FR44 →
C8YTM5	—	0.969	C8YTM5 →
Q80Y20	—	0.969	Q80Y20 →
Q8K370	—	0.968	Q8K370 →