PGAM5

Serine/threonine-protein phosphatase PGAM5, mitochondrial · Q96HS1 · PGAM5 on Sugi Atlas →

0 patent compounds predicted against PGAM5, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PGAM5 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Pioglitazone Therapy Targeting Fatigue in Breast Cancer PHASE2RECRUITING
ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma PHASE2COMPLETED
Efficacy of Amlexanox vs. Placebo in Type 2 Diabetic Patients PHASE2COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Safety Study of Infusion of SGT-53 to Treat Solid Tumors PHASE1COMPLETED
Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer EARLY_PHASE1COMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Clotting Genetic Variants, Hormones, and Venous Thrombosis nanCOMPLETED
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas nanRECRUITING
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease nanUNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Genetic Variants Associated With Adolescent Suicide Attempts nanCOMPLETED
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Autophagy/Apoptosis Balance in Placental Vascular Pathologies nanRECRUITING
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML) nanCOMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
Association of Autophagy-related Genes ,LncRNA and SNPs With Colorectal Cancer in Egyptian Population nanCOMPLETED
Mitigating Mitochondrial RNA Release During Aging to Control Inflammation and Senescence nanNOT_YET_RECRUITING
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
Natural History Study of Mitochondrial Myopathy nanRECRUITING
Identification of Etiopathological and Clinical Factors in Persistent Genital Arousal Disorder nanCOMPLETED
Characterization of Diabetes Mellitus in Fibrous Dysplasia/McCune-Albright Syndrome nanWITHDRAWN
Clinical Study of Hydroxytyrosol (HT) in Mitochondrial Diseases nanCOMPLETED
Nicotinamide Levels in Serum, Aqueous Humor, and Tear Film in Glaucoma and Correlations With Mitochondrial Damage-Associated Molecular Patterns (mtDAMPs) and Senescence-Associated Secretory Phenotype (SASP) nanNOT_YET_RECRUITING
Neutrophils as Prognostic Factors in Granulomatosis With Polyangiitis (Formerly Named Wegener's Granulomatosis) nanCOMPLETED
Evaluation of Serum Gasdermin D Level As a Potential Biomarker of Disease Activity in Vitiligo Patients nanUNKNOWN
Skeletal Muscle Regeneration in Survivors of Critical Illness: How to Prevent Satellite Cell Failure? nanRECRUITING
The PRE-OP ENERGY Trial nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a PGAM5 binder may also engage these)

ProteinNameSimilarity
Q562B5 1.000 Q562B5 →
Q8BX10 1.000 Q8BX10 →
Q502L2 0.996 Q502L2 →
B4PY69 0.995 B4PY69 →
Q5FWM4 0.994 Q5FWM4 →
O46084 0.993 O46084 →
B3P9N0 0.993 B3P9N0 →
B4R313 0.993 B4R313 →
Q61CA3 0.992 Q61CA3 →
B4I9J6 0.992 B4I9J6 →
B4L6S9 0.991 B4L6S9 →
Q6GL33 0.991 Q6GL33 →
B3MR30 0.990 B3MR30 →
B4JMM7 0.990 B4JMM7 →
B4M7S0 0.989 B4M7S0 →
Q29HG0 0.987 Q29HG0 →
Q09422 0.987 Q09422 →
B4GXS1 0.987 B4GXS1 →
B4NE96 0.986 B4NE96 →
F4J8C6 0.984 F4J8C6 →
Q84WW3 0.983 Q84WW3 →
Q5XHF8 0.981 Q5XHF8 →
A7Z050 0.980 A7Z050 →
Q22323 0.980 Q22323 →
Q6ZQB6 0.980 Q6ZQB6 →
PPIP5K2 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 0.979 landscape →
Q9VR59 0.979 Q9VR59 →
Q5SNQ7 0.979 Q5SNQ7 →
Q6PFW1 0.978 Q6PFW1 →
P53370 0.978 P53370 →