PHB2

Prohibitin-2 · Q99623 · PHB2 on Sugi Atlas →

0 patent compounds predicted against PHB2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PHB2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Betaine and Peroxisome Biogenesis Disorders PHASE3COMPLETED
Cardioprotective Empagliflozin for Cancer Patients Receiving Doxorubicin PHASE2/PHASE3UNKNOWN
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder PHASE2WITHDRAWN
Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors PHASE1COMPLETED
Glutamine Supplementation in People With Immune Dysregulation EARLY_PHASE1WITHDRAWN
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
Potential Synergistic Effect of Combined Blood Flow Restriction Training and Betaine Supplementation on Skeletal Muscle nanCOMPLETED
Anhydroglucitol in Children With Type 1 Diabetes nanRECRUITING
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis nanCOMPLETED
Effects of Acute Energy Deficit and Aerobic Exercise on Muscle Quality nanCOMPLETED
The PRE-OP ENERGY Trial nanUNKNOWN
The Natural History of Mitochondrial Diseases nanRECRUITING
Mapping Disease Pathways for Biliary Atresia nanRECRUITING
Nutraceutical Composition Containing Natural Products Derivatives on the Modulation of the Endocrine Neuroimmune Axis nanCOMPLETED
Mutations and Phenotypes of Unclassifiable Inherited Bone Marrow Failure Syndromes nanRECRUITING
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Mitochondrial Dysfunction in Phelan-McDermid Syndrome nanCOMPLETED
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
DNA QUANTIFICATION TECHNIQUE AS A INTERPRETATION TOOL IN MITOCHONDRIAL DISEASES nanCOMPLETED
Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science nanRECRUITING
Skeletal Muscle Mitochondrial Abnormalities and the Metabolic Syndrome in PAH nanCOMPLETED
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq) nanRECRUITING
Mitochondrial Disease-associated ImmunoDeficiencies nanRECRUITING
Tissue Sample Study for Mitochondrial Disorders nanENROLLING_BY_INVITATION
Influence of Diabetic Neuropathy on Activation of Brown Adipose Tissue nanUNKNOWN
Genetic Research of Monogenic Obesity in a Pediatric Cohort With Severe and Early Onset Obesity (GENOBE) nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a PHB2 binder may also engage these)

ProteinNameSimilarity
Q5XIH7 1.000 Q5XIH7 →
O35129 1.000 O35129 →
Q5RB19 1.000 Q5RB19 →
Q5ZMN3 1.000 Q5ZMN3 →
Q2HJ97 1.000 Q2HJ97 →
A9UMS3 0.997 A9UMS3 →
Q9ZNT7 0.993 Q9ZNT7 →
O49460 0.992 O49460 →
Q9P7H3 0.992 Q9P7H3 →
Q9SIL6 0.991 Q9SIL6 →
O94550 0.991 O94550 →
H1VAN0 0.990 H1VAN0 →
Q54GI9 0.990 Q54GI9 →
Q9FFH5 0.989 Q9FFH5 →
Q9LK25 0.988 Q9LK25 →
P50085 0.988 P50085 →
H1VPS8 0.988 H1VPS8 →
Q54Q31 0.987 Q54Q31 →
P50093 0.985 P50093 →
P40961 0.985 P40961 →
Q9LY99 0.981 Q9LY99 →
Q9BKU4 0.980 Q9BKU4 →
O04331 0.978 O04331 →
P72655 0.975 P72655 →
O08917 0.974 O08917 →
FLOT1 Flotillin-1 0.973 landscape →
Q08DN8 0.973 Q08DN8 →
Q767L6 0.972 Q767L6 →
Q9Z1E1 0.972 Q9Z1E1 →
Q6PE84 0.971 Q6PE84 →