Sugi Predict

Sugi Predict / Targets / PLA2G2F

PLA2G2F

Group IIF secretory phospholipase A2 · Q9BZM2 · PLA2G2F on Sugi Atlas →

1,842 patent compounds predicted against PLA2G2F, 1,222 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL5157654 SCHEMBL5157654 1.00 6/20
Water Water (SCHEMBL5159364) 0.84 6/20
Water Water (SCHEMBL5159370) 0.84 6/20
SCHEMBL5530394 SCHEMBL5530394 0.82 6/20
SCHEMBL6309980 SCHEMBL6309980 0.60 6/20
SCHEMBL818585 SCHEMBL818585 0.85 5/20
SCHEMBL7168376 SCHEMBL7168376 0.78 5/20
SCHEMBL5790532 SCHEMBL5790532 0.77 5/20
SCHEMBL5788255 SCHEMBL5788255 0.75 5/20
SCHEMBL7164079 SCHEMBL7164079 0.73 5/20
SCHEMBL5763594 SCHEMBL5763594 0.61 5/20
SCHEMBL6283147 SCHEMBL6283147 0.61 5/20
SCHEMBL6285078 SCHEMBL6285078 0.60 5/20
SCHEMBL5764980 SCHEMBL5764980 0.58 5/20
SCHEMBL5762119 SCHEMBL5762119 0.58 5/20
SCHEMBL6312131 SCHEMBL6312131 0.54 5/20
SCHEMBL5766238 SCHEMBL5766238 0.52 5/20
SCHEMBL5763443 SCHEMBL5763443 0.51 5/20
SCHEMBL5766050 SCHEMBL5766050 0.49 5/20
SCHEMBL5764141 SCHEMBL5764141 0.49 5/20

Clinical trials — most relevant to PLA2G2F by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Comparison of Simvastatin Versus Simvastatin/Ezetimibe on Small Dense Low -Density Lipoprotein (LDL) PHASE4COMPLETED
Eicosapentaenoic Acid Cerebral Vasospasm Therapy Study PHASE4COMPLETED
A Randomized Controlled Pilot Trial of Indomethacin in Acute Pancreatitis PHASE3COMPLETED
European Celecoxib Trial in Primary Breast Cancer PHASE3COMPLETED
Aspirin and Renal Disease Progression in Patients With Type 2 Diabetes PHASE3UNKNOWN
Combined Treatment of Methotrexate + Glucocorticoids Versus Glucocorticoids Alone in Patients With PM and DM PHASE3COMPLETED
Efficacy and Safety of Carica Papaya in Dengue Fever: A Randomised Clinical Trial PHASE3COMPLETED
Effectiveness of Vitamin D in Primary Dysmenorrhoea PHASE3COMPLETED
Obinutuzumab Induced Decreases of PLA2R Antibodies in Membranous Nephropathy: a Pilot Study PHASE2/PHASE3RECRUITING
Lovaza's Effect on the Activation of Platelets PHASE2COMPLETED
Phase II Study Assessing Safety and Efficacy of APL-2 in Glomerulopathies PHASE2COMPLETED
Belimumab With Rituximab for Primary Membranous Nephropathy PHASE2RECRUITING
Assessment of Coronary Plaque Composition PHASE1COMPLETED
Acute Pseudophakic Cystoid Macular Edema Treatment Trial: Intravitreal Ranibizumab Versus Triamcinolone Acetonide PHASE1COMPLETED
Plasma Free Fatty Acids Profile As A Diagnostic Tool For Acute Ischemic Stroke nanCOMPLETED
Physiopathology of Pulmonary Arterial Hypertension: Mechanistic Studies nanUNKNOWN
Mucomyst for Hepatitis C nanSUSPENDED
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish) nanUNKNOWN
PET Imaging of DHA Metabolism nanCOMPLETED
In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer nanCOMPLETED
Lipoprotein-associated Phospholipase A2 in Patients With Type 2 Diabetes nanCOMPLETED
Role of Anti-mouse PLA2R1 ELISA in Membranous Nephropathy nanCOMPLETED
Relation Between Prostaglandin E2 Metabolite Levels and the Development of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Neonates nanRECRUITING
Role of PLA2G1B During HIV Infection nanUNKNOWN
Positron Emission Tomography (PET) to Study Brain Signaling nanCOMPLETED
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma nanRECRUITING
The Association Between Post-ERCP Acute Pancreatitis and Various Genetic Mutations nanCOMPLETED
Investigation of Lipoxin A4, Annexin A1 and Interleukin-1 Beta Levels in Individuals With Periodontitis. nanCOMPLETED
High Dose Omega-3 Fatty Acids in the Treatment of Sport Related Concussions nanCOMPLETED
Molecular Markers of Human Sperm Function nanWITHDRAWN

Related proteins — ESM-2 sequence neighbours (a PLA2G2F binder may also engage these)

ProteinNameSimilarity
Q9QZT4 — 1.000 Q9QZT4 →
P00615 — 0.996 P00615 →
P30811 — 0.996 P30811 →
P20146 — 0.995 P20146 →
Q9PVE9 — 0.994 Q9PVE9 →
Q9PUH8 — 0.994 Q9PUH8 →
Q9DF33 — 0.994 Q9DF33 →
Q9W7J4 — 0.994 Q9W7J4 →
Q9PVF1 — 0.994 Q9PVF1 →
Q45Z27 — 0.994 Q45Z27 →
P00611 — 0.994 P00611 →
Q6H3D0 — 0.994 Q6H3D0 →
P23028 — 0.994 P23028 →
Q9PUH9 — 0.994 Q9PUH9 →
Q9PUI0 — 0.993 Q9PUI0 →
Q7ZTA7 — 0.993 Q7ZTA7 →
Q9PUH2 — 0.993 Q9PUH2 →
Q9PVF0 — 0.993 Q9PVF0 →
F8J2D2 — 0.993 F8J2D2 →
P80966 — 0.993 P80966 →
P00619 — 0.993 P00619 →
Q9PRG0 — 0.993 Q9PRG0 →
Q802I1 — 0.993 Q802I1 →
Q4VRI5 — 0.993 Q4VRI5 →
Q2HZ28 — 0.993 Q2HZ28 →
G9I930 — 0.992 G9I930 →
Q9PUH3 — 0.992 Q9PUH3 →
Q92086 — 0.992 Q92086 →
F8J2D0 — 0.992 F8J2D0 →
Q6H3C7 — 0.992 Q6H3C7 →