Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 20/20 | 0.55 |
| ▸ | PLA2G10 | O15496 | 7/20 | 0.52 |
| ▸ | PLA2G2E | Q9NZK7 | 7/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 6/20 | 0.52 |
| ▸ | PLA2G2D | Q9UNK4 | 6/20 | 0.52 |
| ▸ | PLA2G5 | P39877 | 6/20 | 0.51 |
| ▸ | PLA2G2F | Q9BZM2 | 5/20 | 0.51 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.51 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.51 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.51 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.51 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5762562 | 0.93 | PLA2G2A (0.59) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G2D | |
| SCHEMBL5766238 | 0.90 | PLA2G2A (0.55) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G2D | |
| SCHEMBL5766050 | 0.88 | PLA2G2A (0.53) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G2D | |
| SCHEMBL5764141 | 0.87 | PLA2G2A (0.53) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G2D | |
| SCHEMBL5764234 | 0.87 | PLA2G2A (0.53) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G2D | |
| SCHEMBL7655846 | 0.86 | PLA2G2A (0.56) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G2D | |
| SCHEMBL5762592 | 0.86 | PLA2G2A (0.57) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G2D | |
| SCHEMBL5763594 | 0.81 | PLA2G2A (0.61) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G2D | |
| SCHEMBL5765719 | 0.80 | PLA2G2A (0.53) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G2D | |
| SCHEMBL5764980 | 0.79 | PLA2G2A (0.58) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091738-B1 | BICYCLIC sPLA 2 INHIBITORS | LILLY CO ELI (US) | 2006-12-06 | — | — | EP | claimed |
| EP-1091738-A4 | BICYCLIC sPLA 2 INHIBITORS | LILLY CO ELI (US) | 2003-03-05 | — | — | EP | claimed |
| US-6384041-B1 | ANTIINFLAMMATORY AGENT, TREATMENT OF SHOCK AND ENZYME INHIBITORS | ELI LILLY AND COMPANY | 2002-05-07 | — | — | US | claimed |
| EP-1091738-A1 | BICYCLIC sPLA 2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-04-18 | — | — | EP | claimed |
| WO-2000000201-A1 | BICYCLIC sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2000-01-06 | — | — | WO | claimed |
| EP-1091738-B1 | BICYCLIC sPLA 2 INHIBITORS | LILLY CO ELI (US) | 2006-12-06 | — | — | EP | disclosed |
| EP-1091738-A4 | BICYCLIC sPLA 2 INHIBITORS | LILLY CO ELI (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6384041-B1 | ANTIINFLAMMATORY AGENT, TREATMENT OF SHOCK AND ENZYME INHIBITORS | ELI LILLY AND COMPANY | 2002-05-07 | — | — | US | disclosed |
| EP-1091738-A1 | BICYCLIC sPLA 2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000000201-A1 | BICYCLIC sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2000-01-06 | — | — | WO | disclosed |