LYAR

Cell growth-regulating nucleolar protein · Q9NX58 · LYAR on Sugi Atlas →

0 patent compounds predicted against LYAR, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to LYAR by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors PHASE2RECRUITING
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
Effects of Cannabidiol (CBD) on the Activation of Autophagy and Inflammation Genes, Functional Consequences in Virologically Controlled HIV-infected Patients PHASE2COMPLETED
QUILT-2.008: Study of ALT-801 With Cisplatin in Patients With Metastatic Melanoma PHASE1/PHASE2COMPLETED
ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma PHASE2COMPLETED
Nilotinib in Huntington's Disease PHASE1UNKNOWN
Cixutumumab and Temsirolimus in Treating Younger Patients With Solid Tumors That Have Recurred or Not Responded to Treatment PHASE1COMPLETED
Everolimus in Combination With Nelarabine, Cyclophosphamide and Etoposide in Lymphoblastic Leukemia/Lymphoma PHASE1COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma nanCOMPLETED
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML) nanCOMPLETED
Immunophenotyping and Xist Gene in AML nanUNKNOWN
Study of Proteins in Head and Neck Cancer Cells nanCOMPLETED
Role of LncRNA H19 in The Regulation of IGF-1R Expression nanCOMPLETED
Epitranscriptomic Blood Biomarkers for Coronary Artery Disease - A Prospective Cohort Study (IHD-EPITRAN) nanUNKNOWN
Expression Pattern of HNRNPH1 and HNRNPK Genes in MPNs nanUNKNOWN
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas nanRECRUITING
Association of Autophagy-related Genes ,LncRNA and SNPs With Colorectal Cancer in Egyptian Population nanCOMPLETED
Maternal Hypertriglyceridaemia Study nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Role of Sorcin and Annexin A3 in Breast Cancer Patients nanUNKNOWN
A Clinical Study on the Efficacy and Safety of Methotrexate (MTX) or Thiotepa (for MTX Intolerance) or Temozolomide (TMZ) Combined With Orelabrutinib and Selinexor in Relapsed/Refractory Primary or Secondary Central Nervous System Lymphoma(SELINA) nanRECRUITING
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults nanCOMPLETED
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma nanCOMPLETED
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes nanUNKNOWN
RibOSE - Glucose and Resistance Exercise Training nanCOMPLETED
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING
Thermogenic Silencer Regulatory Factors in Humans nanACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a LYAR binder may also engage these)

ProteinNameSimilarity
Q6AYK5 1.000 Q6AYK5 →
Q08288 1.000 Q08288 →
Q4R627 0.983 Q4R627 →
E1BTG2 0.981 E1BTG2 →
RRP1B Ribosomal RNA processing protein 1 homolog B 0.980 landscape →
Q5XI01 0.980 Q5XI01 →
D3Z8X7 0.980 D3Z8X7 →
Q3UFB2 0.979 Q3UFB2 →
Q7TN31 0.979 Q7TN31 →
A4FV97 0.979 A4FV97 →
Q91YK2 0.979 Q91YK2 →
Q05CL8 0.978 Q05CL8 →
Q02040 0.978 Q02040 →
Q6AXS3 0.978 Q6AXS3 →
Q62187 0.978 Q62187 →
Q62315 0.978 Q62315 →
O35144 0.978 O35144 →
Q9R207 0.977 Q9R207 →
Q53F19 0.977 Q53F19 →
Q812D1 0.977 Q812D1 →
ERCC5 DNA excision repair protein ERCC-5 0.977 landscape →
Q566R3 0.977 Q566R3 →
TERF2 Telomeric repeat-binding factor 2 0.977 landscape →
Q7ZWE3 0.977 Q7ZWE3 →
Q66T72 0.977 Q66T72 →
A4FV61 0.977 A4FV61 →
LARP7 La-related protein 7 0.976 landscape →
Q28G87 0.976 Q28G87 →
P14629 0.976 P14629 →
O60934 0.976 O60934 →