PPP6R1

Serine/threonine-protein phosphatase 6 regulatory subunit 1 · Q9UPN7 · PPP6R1 on Sugi Atlas →

0 patent compounds predicted against PPP6R1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PPP6R1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Rectal Tacrolimus in the Treatment of Resistant Ulcerative Proctitis PHASE4COMPLETED
The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus PHASE3UNKNOWN
Mitochondrial Oxidation and Insulin Resistance in Burn Patients Treated With Fenofibrate PHASE2/PHASE3WITHDRAWN
A Multicenter Study of NAP (AL-108) in Schizophrenia PHASE2COMPLETED
Everolimus in Treating Patients With Relapsed or Refractory Multiple Myeloma PHASE2COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients PHASE2COMPLETED
Open-label Study on Treatment of Primary Aldosteronism With Everolimus PHASE2COMPLETED
Cixutumumab and Temsirolimus in Treating Patients With Metastatic Prostate Cancer PHASE1/PHASE2COMPLETED
Lapatinib Ditosylate in Treating Patients With Unresectable Liver or Biliary Tract Cancer PHASE2COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Evaluating MED2005 & Nitrostat Bioavailability PHASE1COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome PHASE1COMPLETED
Novel Molecular Targets and Innovative Therapeutic Perspective in Medulloblastoma EARLY_PHASE1RECRUITING
Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer EARLY_PHASE1COMPLETED
Quantification of GADD34 Expression in RA nanCOMPLETED
Immune Signature of Palmoplantar Pustulosis nanCOMPLETED
NGS in Gallbladder Cancer and Response to Treatment nanRECRUITING
Lymphoid Tyrosine Phosphatase Gene Polymorphisms in Inflammatory Bowel Disease nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Protein Synthesis in the Brain of Patients With Fragile X Syndrome nanCOMPLETED
Protein Intake and Step Reduction in Older Adults nanCOMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Evaluation of Blood Protein O-GlcNAcylation Levels in Children nanRECRUITING
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases nanNOT_YET_RECRUITING
Dried Fruit and Postprandial Glycemia Trial nanUNKNOWN
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes nanUNKNOWN
IVF Outcome in Polycystic Ovary Syndrome Patients nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a PPP6R1 binder may also engage these)

ProteinNameSimilarity
Q7TSI3 1.000 Q7TSI3 →
O75170 0.997 O75170 →
Q8R3Q2 0.996 Q8R3Q2 →
Q922D4 0.994 Q922D4 →
PPP6R3 Serine/threonine-protein phosphatase 6 regulatory subunit 3 0.994 landscape →
Q9LYZ7 0.994 Q9LYZ7 →
Q6NRF1 0.994 Q6NRF1 →
Q5F471 0.993 Q5F471 →
Q76LL6 0.992 Q76LL6 →
Q58HI1 0.992 Q58HI1 →
Q8TDY4 0.992 Q8TDY4 →
Q1L8G6 0.992 Q1L8G6 →
Q17QK1 0.991 Q17QK1 →
Q6ZPS6 0.991 Q6ZPS6 →
F1RCR6 0.990 F1RCR6 →
Q7Z3E5 0.990 Q7Z3E5 →
O43310 0.990 O43310 →
Q32N92 0.990 Q32N92 →
Q9BQK8 0.990 Q9BQK8 →
Q6NRI0 0.990 Q6NRI0 →
O95343 0.990 O95343 →
A9JR78 0.990 A9JR78 →
Q1LYM3 0.990 Q1LYM3 →
A2ARM1 0.990 A2ARM1 →
Q1LUT1 0.990 Q1LUT1 →
A3KMV1 0.990 A3KMV1 →
Q3UB74 0.989 Q3UB74 →
Q5XG71 0.989 Q5XG71 →
Q8TBC3 0.989 Q8TBC3 →
E9PVA8 0.989 E9PVA8 →