PPT1

Palmitoyl-protein thioesterase 1 · P50897 · PPT1 on Sugi Atlas →

0 patent compounds predicted against PPT1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PPT1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Cystagon to Treat Infantile Neuronal Ceroid Lipofuscinosis PHASE4COMPLETED
Hereditary Sensory Neuropathy Serine Trial PHASE2UNKNOWN
Metabolic Cofactor Supplementation in Alzheimer's Disease (AD) and Parkinson's Disease (PD) Patients PHASE2COMPLETED
Clinical Trial of 2-HOBA in Pulmonary Arterial Hypertension PHASE2NOT_YET_RECRUITING
Metabolic Cofactor Supplementation in Obese Patients With Non-Alcoholic Fatty Liver Disease PHASE2COMPLETED
Study of HuCNS-SC Cells in Patients With Infantile or Late Infantile Neuronal Ceroid Lipofuscinosis (NCL) PHASE1COMPLETED
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides PHASE1COMPLETED
Insulin Regulation of Lipolysis and Lipolysis Proteins EARLY_PHASE1RECRUITING
Targeting zDHHC Enzymes to Counteract Alzheimer's Disease nanNOT_YET_RECRUITING
Structural Network on Prostate Cancer in the French Greater West Region nanCOMPLETED
Effect of Omega-3 Fatty Acids Supplementation on Hypertriglyceridemia in Pediatric Patients With Obesity. nanCOMPLETED
RCDP Natural History Study nanUNKNOWN
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
Nutritional Therapy of the Deficits of Oxidation Mitochondrial of the Fatty Acids nanCOMPLETED
Lipodystrophy Connect Patient Registry nanCOMPLETED
Genetic and Environmental Determinants of Triglycerides (GOLDN) nanCOMPLETED
Role of Dairy Products in Weight Maintenance nanCOMPLETED
Pharmacogenetics of Hypertriglyceridemia in Hispanics nanCOMPLETED
Influence of WNT4 VEZT FSHB and SIRT1 SNPs in Endometriosis: a Case Control Study of the Sardinian Population nanUNKNOWN
Development of Biomarker for Development of Non-Alcoholic Steatohepatitis (NASH) in Children nanWITHDRAWN
The Effect Of DAAs on miRNA-122 And Insulin Resistance In Chronic HCV Patients nanUNKNOWN
Fatty Acid Oxidation Defects and Insulin Sensitivity nanCOMPLETED
for Adipose Tissue DIabetes VAriants (fATDIVA) nanCOMPLETED
A 12 Week, 3-Period Study to Evaluate the Effects of a Dietary Supplement on Lipid Metabolism nanCOMPLETED
The Classification and Cause of Leukodystrophies of Unknown Cause nanCOMPLETED
A Prospective Study of the Disease Characteristics of Adult Patients With Long Chain Fatty Acid Oxidation Disorders nanCOMPLETED
Canagliflozin on Liver Inflammation Damage in Type 2 Diabetes Patients With Nonalcoholic Fatty Liver Disease nanUNKNOWN
Fatty Acid Metabolism and Insulin Sensitivity: the Role of Endurance Exercise nanCOMPLETED
Recovery With Exogenous Ketones and Antipsychotics nanRECRUITING
Genes Involved in Lipid Disorders nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PPT1 binder may also engage these)

ProteinNameSimilarity
P45478 1.000 P45478 →
P45479 1.000 P45479 →
Q8HXW6 1.000 Q8HXW6 →
O88531 0.996 O88531 →
Q9UMR5 0.977 Q9UMR5 →
Q9HB40 0.971 Q9HB40 →
O70489 0.971 O70489 →
Q641Z7 0.970 Q641Z7 →
Q8WMP9 0.968 Q8WMP9 →
Q9MYY0 0.968 Q9MYY0 →
Q3MI05 0.967 Q3MI05 →
Q6DYE8 0.966 Q6DYE8 →
Q8VEB4 0.965 Q8VEB4 →
Q01460 0.965 Q01460 →
Q5R9N3 0.965 Q5R9N3 →
O35448 0.965 O35448 →
Q6PCJ9 0.964 Q6PCJ9 →
Q920A5 0.964 Q920A5 →
Q675A5 0.964 Q675A5 →
Q9UHG3 0.963 Q9UHG3 →
O77588 0.963 O77588 →
Q5R5M5 0.963 Q5R5M5 →
Q5R748 0.963 Q5R748 →
Q8CFX1 0.963 Q8CFX1 →
ENPP3 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 0.963 landscape →
Q1JQA0 0.962 Q1JQA0 →
O95479 0.962 O95479 →
Q9BRR6 0.962 Q9BRR6 →
W8E7D1 0.962 W8E7D1 →
Q920A6 0.962 Q920A6 →