Sugi Predict

Sugi Predict / Targets / PRAP1

PRAP1

Proline-rich acidic protein 1 · Q96NZ9 · PRAP1 on Sugi Atlas →

2,411 patent compounds predicted against PRAP1, 2,079 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Azd2461 Azd2461 (SCHEMBL77012) 1.00 1/20
SCHEMBL76871 SCHEMBL76871 0.84 1/20
SCHEMBL87500 SCHEMBL87500 0.84 1/20
SCHEMBL78156 SCHEMBL78156 0.83 1/20
SCHEMBL78202 SCHEMBL78202 0.82 1/20
SCHEMBL79067 SCHEMBL79067 0.82 1/20
SCHEMBL86880 SCHEMBL86880 0.82 1/20
SCHEMBL86912 SCHEMBL86912 0.82 1/20
SCHEMBL87049 SCHEMBL87049 0.82 1/20
SCHEMBL8021689 SCHEMBL8021689 0.82 1/20
SCHEMBL77298 SCHEMBL77298 0.82 1/20
SCHEMBL87169 SCHEMBL87169 0.82 1/20
SCHEMBL3665158 SCHEMBL3665158 0.82 1/20
SCHEMBL78550 SCHEMBL78550 0.81 1/20
SCHEMBL3667787 SCHEMBL3667787 0.81 1/20
SCHEMBL77230 SCHEMBL77230 0.81 1/20
SCHEMBL77632 SCHEMBL77632 0.81 1/20
SCHEMBL87240 SCHEMBL87240 0.81 1/20
SCHEMBL78306 SCHEMBL78306 0.80 1/20
SCHEMBL77315 SCHEMBL77315 0.79 1/20

Clinical trials — most relevant to PRAP1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Peptide Vaccinations to Treat Patients With Low-Risk Myeloid Cancers PHASE2COMPLETED
Roflumilast in Non-CF Bronchiectasis Study (2019) PHASE2COMPLETED
A Study Evaluating Megestrol Acetate Modulation in Hormone Receptor Positive Advanced Breast Cancer PHASE2UNKNOWN
MABp1 IN HIDRADENITIS SUPPURATIVA REFRACTORY TO ADALIMUMAB PHASE2COMPLETED
Study of Sorafenib and Docetaxel in Metastatic Prostate Cancer PHASE2COMPLETED
Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and Safety PHASE2COMPLETED
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients PHASE2COMPLETED
Depletion of Serum Amyloid P Component to Enhance the Immune Response to DNA Vaccination PHASE1/PHASE2COMPLETED
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS nanCOMPLETED
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis nanUNKNOWN
Observational Study of Sepsis and Pneumonia to Develop Diagnostic Tests nanUNKNOWN
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD) nanCOMPLETED
Protein Expression as a Potential Diagnostic Biomarker of Cervical Dysplasia and/or Cancer nanCOMPLETED
IL-17 Role in Variants of Psoriasis nanCOMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Urine and Serum Concentrations of Pregnancy-Associated Compounds During Gestation nanCOMPLETED
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Serum Talin-1 and Cripto-1 in Colorectal Cancer nanNOT_YET_RECRUITING
The Role of Maspin in Colorectal Carcinoma, an Immunohistochemical Study nanNOT_YET_RECRUITING
Biomarkers in Idiopathic Juvenile Arthritis nanUNKNOWN
Proteomics of Primary Hyperoxaluria Type 1 nanCOMPLETED
Aswan Heart Centre - Egyptian Healthy Volunteers nanRECRUITING
Novel Biomarkers of Preeclampsia, Aquaporin, Fatty Acid, and S110B nanCOMPLETED
Biomarkers in Patients Undergoing Transrectal Ultrasound Prostate Biopsy nanCOMPLETED
Prohepcidin, Inflammation and Iron Homeostasis in Hemodialysis Patients With Chronic Hepatitis C nanCOMPLETED
Discovery of Soluble Biomarkers for Pancreatic Cancer Using Innovative All-Patient Inclusive Methodology nanRECRUITING
Prospective Genetic Study in Patients With Ovarian Insufficiency nanUNKNOWN
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma nanRECRUITING
Reducing Heart Failure Risk in Late-Life With Physical Activity nanNOT_YET_RECRUITING
Predictive Value of Maternal Blood Protein Signatures in Preterm Birth nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PRAP1 binder may also engage these)

ProteinNameSimilarity
Q80XD8 — 0.997 Q80XD8 →
Q9ES75 — 0.989 Q9ES75 →
Q5NRQ1 — 0.985 Q5NRQ1 →
P18844 — 0.985 P18844 →
Q9UK85 — 0.984 Q9UK85 →
P13207 — 0.984 P13207 →
O55189 — 0.984 O55189 →
P23943 — 0.983 P23943 →
P17322 — 0.983 P17322 →
Q9XSX7 — 0.983 Q9XSX7 →
Q5JX71 — 0.983 Q5JX71 →
O76061 — 0.982 O76061 →
Q2T9P9 — 0.982 Q2T9P9 →
Q5NRQ0 — 0.982 Q5NRQ0 →
P05305 — 0.982 P05305 →
P20800 — 0.982 P20800 →
D3ZUE1 — 0.982 D3ZUE1 →
Q6MG51 — 0.982 Q6MG51 →
TET3 Methylcytosine dioxygenase TET3 0.982 landscape →
Q5BK39 — 0.982 Q5BK39 →
Q9Z1R4 — 0.982 Q9Z1R4 →
Q1RMJ9 — 0.982 Q1RMJ9 →
Q8SQD7 — 0.982 Q8SQD7 →
P12961 — 0.981 P12961 →
Q9QXP4 — 0.981 Q9QXP4 →
P13206 — 0.981 P13206 →
Q0D2H9 — 0.981 Q0D2H9 →
Q80VY2 — 0.981 Q80VY2 →
Q5NRP8 — 0.981 Q5NRP8 →
P29169 — 0.981 P29169 →