PSMD6 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL1478606	0.58	12/20
SCHEMBL607010	0.56	12/20
SCHEMBL608381	0.53	12/20
SCHEMBL3170187	0.51	12/20
SCHEMBL606616	0.51	12/20
SCHEMBL1477637	0.57	11/20
SCHEMBL607972	0.55	11/20
SCHEMBL608782	0.54	11/20
SCHEMBL609278	0.54	11/20
SCHEMBL607553	0.54	11/20
SCHEMBL605822	0.54	11/20
SCHEMBL606932	0.53	11/20
SCHEMBL1477893	0.53	11/20
SCHEMBL608362	0.53	11/20
SCHEMBL608599	0.53	11/20
SCHEMBL1327441	0.53	11/20
SCHEMBL605129	0.52	11/20
SCHEMBL3170843	0.52	11/20
SCHEMBL608009	0.52	11/20
SCHEMBL1478157	0.52	11/20

Clinical trials — most relevant to PSMD6 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
A Prospective, Placebo Controlled, Double-Blind, Cross-over Study on the Effects of a Probiotic Preparation (VSL#3) on Metabolic Profile, Intestinal Permeability, Microbiota, Cytokines and Chemokines Expression and Other Inflammatory Markers in Pediatric Patients With Crohn's Disease	PHASE4	UNKNOWN
Hypoxia-inducible Factor Prolyl Hydroxylase Inhibitors on Sarcopenia in Hemodialysis Patients	PHASE4	NOT_YET_RECRUITING
Biologic Correlative Taxotere/AC	PHASE2	COMPLETED
Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes	PHASE2	UNKNOWN
Phase II Study of Vandetanib in Individuals With Kidney Cancer	PHASE2	COMPLETED
Doxorubicin and Bortezomib in Treating Patients With Liver Cancer	PHASE2	COMPLETED
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy	PHASE2	COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck	PHASE1	COMPLETED
Study of Patients With Stage IV Malignant Melanoma Using PS-341 (Bortezomib, Velcade) and Interferon-alpha-2b in Malignant Melanoma	PHASE1	COMPLETED
Study of Irinotecan and Bortezomib in Children With Recurrent/Refractory Neuroblastoma	PHASE1	COMPLETED
Low Dose Melphalan and Bortezomib for AML and High-Risk MDS	nan	COMPLETED
Effect of Diaphragm Stimulation During Surgery	nan	COMPLETED
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors	nan	NOT_YET_RECRUITING
Evaluation of Proteasome as a Marker of Hepatocellular Carcinoma in Cirrhotic Patients Following Curative Treatment	nan	UNKNOWN
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men	nan	RECRUITING
Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract	nan	UNKNOWN
The PREServation of MUScle Function in Critically Ill Patients (PRESMUS)	nan	UNKNOWN
Collection of Blood Samples for DNA in Motor Neuron Disease	nan	COMPLETED
Establishment of Human Cellular Disease Models for Wilson Disease	nan	COMPLETED
Cardiovascular Complications of Carfilzomib Treatment	nan	UNKNOWN
Exercise Therapy to Reduce Heart Failure Symptoms; Sorting Mechanisms of Benefit	nan	COMPLETED
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis	nan	UNKNOWN
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk	nan	NOT_YET_RECRUITING
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults	nan	COMPLETED
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia	nan	RECRUITING
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure	nan	COMPLETED
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)	nan	RECRUITING
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a PSMD6 binder may also engage these)

Protein	Name	Similarity
Q99JI4	—	1.000	Q99JI4 →
Q3T0B2	—	1.000	Q3T0B2 →
Q9V3G7	—	1.000	Q9V3G7 →
Q0CNR3	—	0.997	Q0CNR3 →
Q8W425	—	0.996	Q8W425 →
Q93Y35	—	0.995	Q93Y35 →
Q55C75	—	0.995	Q55C75 →
Q9C5Z3	—	0.995	Q9C5Z3 →
A6H7B5	—	0.993	A6H7B5 →
Q8W575	—	0.992	Q8W575 →
Q1E170	—	0.992	Q1E170 →
Q20585	—	0.992	Q20585 →
Q10335	—	0.992	Q10335 →
Q5ZJF1	—	0.991	Q5ZJF1 →
Q20938	—	0.991	Q20938 →
A5AAA4	—	0.991	A5AAA4 →
Q17D30	—	0.991	Q17D30 →
Q5B973	—	0.991	Q5B973 →
Q7Q068	—	0.991	Q7Q068 →
B3MCZ5	—	0.990	B3MCZ5 →
Q4R898	—	0.990	Q4R898 →
Q5RFS2	—	0.990	Q5RFS2 →
A7F3L0	—	0.990	A7F3L0 →
Q28IV6	—	0.990	Q28IV6 →
O88543	—	0.990	O88543 →
A1D6T6	—	0.989	A1D6T6 →
A4R796	—	0.989	A4R796 →
Q4WY08	—	0.989	Q4WY08 →
A1CKN7	—	0.989	A1CKN7 →
A6SM77	—	0.988	A6SM77 →