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RAB2A

Ras-related protein Rab-2A · P61019 · RAB2A on Sugi Atlas →

50 patent compounds predicted against RAB2A, 50 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL15647854 SCHEMBL15647854 1.00 1/20
SCHEMBL15832860 SCHEMBL15832860 0.84 1/20
SCHEMBL15832891 SCHEMBL15832891 0.84 1/20
SCHEMBL15832859 SCHEMBL15832859 0.81 1/20
SCHEMBL15832866 SCHEMBL15832866 0.81 1/20
SCHEMBL21247198 SCHEMBL21247198 0.80 1/20
SCHEMBL15832889 SCHEMBL15832889 0.78 1/20
SCHEMBL14096464 SCHEMBL14096464 0.78 1/20
SCHEMBL15832875 SCHEMBL15832875 0.78 1/20
SCHEMBL15832884 SCHEMBL15832884 0.78 1/20
SCHEMBL15832879 SCHEMBL15832879 0.76 1/20
SCHEMBL15832887 SCHEMBL15832887 0.67 1/20
SCHEMBL15832845 SCHEMBL15832845 0.66 1/20
SCHEMBL16002090 SCHEMBL16002090 0.65 1/20
SCHEMBL16002213 SCHEMBL16002213 0.65 1/20
SCHEMBL15832883 SCHEMBL15832883 0.65 1/20
SCHEMBL8288608 SCHEMBL8288608 0.64 1/20
SCHEMBL15832857 SCHEMBL15832857 0.64 1/20
SCHEMBL16002160 SCHEMBL16002160 0.64 1/20
SCHEMBL15832911 SCHEMBL15832911 0.64 1/20

Clinical trials — most relevant to RAB2A by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Study of Hydroxychloroquine in Combination With Gemcitabine/Abraxane in Pancreatic Cancer PHASE1/PHASE2COMPLETED
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
Phase 2 Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin for Non-Small Cell Lung Cancer With KRAS or EGFR Activation PHASE2COMPLETED
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Nilotinib in Huntington's Disease PHASE1UNKNOWN
Effects of Lithium Therapy on Blood-based Therapeutic Targets in Parkinson's Disease. PHASE1COMPLETED
Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial nanRECRUITING
Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy Patients nanRECRUITING
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease nanUNKNOWN
Fox BioNet Project: LRRK2-002 nanCOMPLETED
AV133 Longitudinal Imaging Study in Patients With Early and Prdromal Parkinson's Disease nanRECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Gene Analysis of Parkinson's Disease nanCOMPLETED
Parkinson's Families Project nanRECRUITING
Consortium On Risk for Early-onset Parkinson's Disease (CORE PD) nanCOMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Clinical Genetics Branch Eligibility Screening Survey nanNOT_YET_RECRUITING
Prevalence and Characterization of Pain in RASopathies nanUNKNOWN
Non Motor Symptoms in Glucocerebrosidase-related Parkinson's Disease nanENROLLING_BY_INVITATION
Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies nanRECRUITING
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
RASopathy Biorepository nanRECRUITING
Genetics of Rolandic Epilepsy nanCOMPLETED
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Pubertal Development in Patients with RASopathies nanRECRUITING
Rolandic Epilepsy Genomewide Association International Study nanCOMPLETED
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Gait in Rare Diseases nanCOMPLETED
Rostock International Parkinson's Disease Study (ROPAD) nanCOMPLETED
Genetic Evaluation of NF1 and Scoliosis Patients nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a RAB2A binder may also engage these)

ProteinNameSimilarity
P61105 — 1.000 P61105 →
Q90965 — 1.000 Q90965 →
Q5R6B6 — 1.000 Q5R6B6 →
O18333 — 1.000 O18333 →
Q05975 — 1.000 Q05975 →
Q4R4X6 — 1.000 Q4R4X6 →
P53994 — 1.000 P53994 →
Q01971 — 1.000 Q01971 →
P49104 — 0.999 P49104 →
P05712 — 0.998 P05712 →
Q38922 — 0.997 Q38922 →
P36863 — 0.995 P36863 →
Q39570 — 0.993 Q39570 →
P49103 — 0.993 P49103 →
P36409 — 0.991 P36409 →
Q8WUD1 — 0.991 Q8WUD1 →
P92963 — 0.990 P92963 →
Q9FIF9 — 0.989 Q9FIF9 →
P59279 — 0.988 P59279 →
Q39572 — 0.986 Q39572 →
P28188 — 0.984 P28188 →
P17610 — 0.984 P17610 →
Q9FK68 — 0.984 Q9FK68 →
Q9S810 — 0.984 Q9S810 →
P46638 — 0.984 P46638 →
Q40521 — 0.984 Q40521 →
Q40723 — 0.983 Q40723 →
Q3MHP2 — 0.983 Q3MHP2 →
O35509 — 0.983 O35509 →
Q15907 — 0.983 Q15907 →