Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | RAB7A | P51149 | 10/20 | 0.66 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | CDC42 | P60953 | 1/20 | 0.64 |
| ▸ | RAB2A | P61019 | 1/20 | 0.64 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.59 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15272485 | 0.88 | KDM4E (0.72) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL21247198 | 0.83 | ALDH1A1 (1.00) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL15832879 | 0.80 | RAB7A (0.76) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL15832859 | 0.80 | RAB7A (1.00) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL15647854 | 0.78 | RAB7A (1.00) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL21260779 | 0.77 | ALDH1A1 (0.66) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL15832884 | 0.74 | RAB7A (1.00) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL21247180 | 0.72 | NOD1 (1.00) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL15832891 | 0.72 | RAB7A (1.00) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL21260639 | 0.70 | ANO1 (0.69) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376452-B2 | Rab7 GTPase inhibitors and related methods of treatment | ST. UNM (US) | 2016-06-28 | — | — | US | disclosed |
| US-9376452-B2 | Rab7 GTPase inhibitors and related methods of treatment | ST. UNM (US) | 2016-06-28 | — | — | US | disclosed |
| US-20140248268-A1 | Rab7 GTPase Inhibitors and Related Methods of Treatment | THE REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2014-09-04 | — | — | US | disclosed |
| US-20140248268-A1 | Rab7 GTPase Inhibitors and Related Methods of Treatment | THE REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2014-09-04 | — | — | US | disclosed |
| US-8765803-B1 | Rab7 GTPase inhibitors and related methods of treatment | STC.UNM (US) | 2014-07-01 | — | — | US | disclosed |
| US-8765803-B1 | Rab7 GTPase inhibitors and related methods of treatment | STC.UNM (US) | 2014-07-01 | — | — | US | disclosed |
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140248268-A1 | Rab7 GTPase Inhibitors and Related Methods of Treatment | RAB7A, RAB5B, RAB1A | KMT2A 4280/4885ALDH1A1 4235/4885MAPT 1628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.