SCHEMBL631591

SCHEMBL631591

CC(C)(C)c1ccccc1N1CCN(C(=O)CC(=O)O)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RBP4 P02753 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30227111 1.00 RBP4 (1.00) RBP4
SCHEMBL630507 0.88 RBP4 (0.78) RBP4
SCHEMBL766250 0.85 RBP4 (0.74) RBP4
SCHEMBL633153 0.85 RBP4 (0.74) RBP4
SCHEMBL27873708 0.84 RBP4 (0.80) RBP4
SCHEMBL766147 0.84 RBP4 (0.72) RBP4
SCHEMBL18255868 0.83 RBP4 (0.71) RBP4
SCHEMBL766188 0.83 RBP4 (0.71) RBP4
SCHEMBL630631 0.83 RBP4 (0.71) RBP4
SCHEMBL766160 0.83 RBP4 (0.71) RBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250241902-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION BELITE BIO INC (US) 2025-07-31 US claimed
US-20240248099-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION BELITE BIO, LLC 2024-07-25 US claimed
EP-4340701-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION Belite Bio, LLC (US) 2024-03-27 EP claimed
CN-117440774-A Biomarkers of age-related macular degeneration 倍亮生物有限责任公司 2024-01-23 CN claimed
WO-2022246238-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION BELITE BIO, LLC (US) 2022-11-24 WO claimed
US-8853215-B2 Derivatives of N-acyl-N′-phenylpiperazine useful (inter alia) for the prophylaxis or treatment of diabetes TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2014-10-07 US claimed
US-20120071489-A1 DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-03-22 US claimed
EP-2419413-A1 DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES Takeda Pharmaceutical Company Limited (JP) 2012-02-22 EP claimed
WO-2010119992-A1 DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-10-21 WO claimed
US-20250241902-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION BELITE BIO INC (US) 2025-07-31 US disclosed
US-20240248099-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION BELITE BIO, LLC 2024-07-25 US disclosed
EP-4340701-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION Belite Bio, LLC (US) 2024-03-27 EP disclosed
CN-117440774-A Biomarkers of age-related macular degeneration 倍亮生物有限责任公司 2024-01-23 CN disclosed
WO-2023200766-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION BELITE BIO, INC (US) 2023-10-19 WO disclosed
CN-102459209-A Derivatives of N-acyl-N' -phenylpiperazines for the prevention or treatment of diabetes (etc.) TAKEDA PHARMACEUTICAL 2012-05-16 CN disclosed
US-20120071489-A1 DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-03-22 US disclosed
US-20120071489-A1 DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-03-22 US disclosed
US-20120071489-A1 DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-03-22 US disclosed
EP-2419413-A1 DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES Takeda Pharmaceutical Company Limited (JP) 2012-02-22 EP disclosed
WO-2010119992-A1 DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071489-A1 DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES RBP4, RBP1, FABP4 RBP4 1/4885
US-20250241902-A1 METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION PDE6C, SERPINA6, PDE6H RBP4 11/4885
US-20240248099-A1 BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION AGER, RBP4, RBP1 RBP4 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.