RPS11 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL31246618	0.65	15/20
SCHEMBL24176574	1.00	14/20
SCHEMBL29596176	1.00	14/20
SCHEMBL31246964	1.00	14/20
SCHEMBL31246552	0.63	14/20
SCHEMBL31227441	0.62	14/20
SCHEMBL31227395	0.60	14/20
SCHEMBL31246768	0.59	14/20
SCHEMBL31246904	0.59	14/20
SCHEMBL31246869	0.58	14/20
SCHEMBL31227052	0.55	14/20
SCHEMBL31246799	0.55	14/20
SCHEMBL31246750	0.55	14/20
SCHEMBL31246571	0.55	14/20
SCHEMBL31247006	0.51	14/20
SCHEMBL31227365	0.50	14/20
SCHEMBL31246572	0.75	13/20
SCHEMBL31246624	0.72	13/20
SCHEMBL31246509	0.71	13/20
SCHEMBL31246511	0.69	13/20

Clinical trials — most relevant to RPS11 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes	PHASE4	UNKNOWN
Sirolimus Treatment for Newly Diagnosed Primary Acquired PRCA	PHASE4	COMPLETED
Tacrolimus Treatment for Refractory PRCA	PHASE4	UNKNOWN
Sirolimus Treatment for Refractory PRCA	PHASE4	COMPLETED
Mobilization of Stem Cells With G-CSF for Collection From Patients With Diamond-Blackfan Anemia	PHASE2	COMPLETED
Cixutumumab and Temsirolimus in Treating Patients With Metastatic Prostate Cancer	PHASE1/PHASE2	COMPLETED
Everolimus for Children With Recurrent or Progressive Ependymoma	PHASE2	COMPLETED
Assessing the Safety, Tolerability, and Efficacy of APR-2020 in Pediatric and Adolescent Subjects With RPS19 Deficient Diamond-Blackfan Anemia	PHASE1	RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma	PHASE1	COMPLETED
Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer	PHASE1	WITHDRAWN
Mobilization of CD34+ Peripheral Blood Stem Cells in Patients With Diamond Blackfan Anemia Syndrome (DBAS)	nan	RECRUITING
Personalized Medicine Program on Myelodysplastic Syndromes: Characterization of the Patient's Genome for Clinical Decision Making and Systematic Collection of Real World Data to Improve Quality of Health Care	nan	COMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia	nan	NOT_YET_RECRUITING
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Cytomegalovirus (CMV) MicroRNA Expression in Vivo and Immune Evasion Correlates	nan	COMPLETED
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma	nan	COMPLETED
Role of Sorcin and Annexin A3 in Breast Cancer Patients	nan	UNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus	nan	COMPLETED
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
Effect of Branched Chain Amino Acids on Muscle	nan	COMPLETED
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML)	nan	COMPLETED
Genetic Variation in TRAF3IP2 (rs13190932)	nan	RECRUITING
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic	nan	COMPLETED
miR-155 Expression in Episodic and Chronic Migraine	nan	UNKNOWN
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact	nan	UNKNOWN
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma	nan	COMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Rapamycin as a Means of Interference With Reconsolidation of Posttraumatic Stress Disorder-related Traumatic Memory	nan	COMPLETED
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress	nan	WITHDRAWN
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants.	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a RPS11 binder may also engage these)

Protein	Name	Similarity
Q3T0V4	—	1.000	Q3T0V4 →
P62281	—	1.000	P62281 →
P61270	—	1.000	P61270 →
Q54S90	—	1.000	Q54S90 →
P62282	—	1.000	P62282 →
G1TRM4	—	1.000	G1TRM4 →
Q9XSU4	—	1.000	Q9XSU4 →
P41115	—	1.000	P41115 →
P0CX47	—	0.998	P0CX47 →
Q9M5M1	—	0.998	Q9M5M1 →
P0CX48	—	0.998	P0CX48 →
Q292D0	—	0.998	Q292D0 →
A0A1D8PN83	—	0.998	A0A1D8PN83 →
O65569	—	0.996	O65569 →
Q0E9B6	—	0.996	Q0E9B6 →
Q6XHX5	—	0.996	Q6XHX5 →
P42756	—	0.995	P42756 →
P52812	—	0.995	P52812 →
P42733	—	0.994	P42733 →
P17093	—	0.991	P17093 →
P16181	—	0.990	P16181 →
P0CT73	—	0.989	P0CT73 →
P0CT74	—	0.989	P0CT74 →
B5Z8J2	—	0.987	B5Z8J2 →
Q1CS69	—	0.987	Q1CS69 →
P25460	—	0.986	P25460 →
Q6AP76	—	0.986	Q6AP76 →
B9E8Q3	—	0.985	B9E8Q3 →
P75546	—	0.985	P75546 →
B2IK57	—	0.985	B2IK57 →