RPS23 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL16189192	0.69	12/20
SCHEMBL16189119	0.68	10/20
SCHEMBL16177128	1.00	9/20
SCHEMBL16177345	1.00	9/20
SCHEMBL16177805	1.00	9/20
SCHEMBL16177066	0.74	9/20
SCHEMBL16177239	0.74	9/20
SCHEMBL16177254	0.73	9/20
SCHEMBL17536518	0.68	9/20
SCHEMBL17536553	0.66	9/20
SCHEMBL17536517	0.66	9/20
SCHEMBL17536519	0.64	9/20
SCHEMBL17536554	0.62	9/20
SCHEMBL16180190	0.81	8/20
SCHEMBL17536515	0.69	8/20
SCHEMBL16177161	0.49	8/20
SCHEMBL16177141	1.00	7/20
SCHEMBL16177219	0.71	7/20
SCHEMBL17536514	0.65	7/20
SCHEMBL17536516	0.60	7/20

Clinical trials — most relevant to RPS23 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes	PHASE4	UNKNOWN
Effect of WHO-yaws Elimination Strategy in Lihir Island, Papua New Guinea	PHASE3	COMPLETED
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients	PHASE2	COMPLETED
Cixutumumab and Temsirolimus in Treating Patients With Metastatic Prostate Cancer	PHASE1/PHASE2	COMPLETED
Phase II Study of Simvastatin Plus Irinotecan, Fluorouracil, and Leucovorin(FOLFIRI) for Metastatic CRC	PHASE2	COMPLETED
ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma	PHASE2	COMPLETED
Everolimus for Children With Recurrent or Progressive Ependymoma	PHASE2	COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma	PHASE1	COMPLETED
Assessing the Safety, Tolerability, and Efficacy of APR-2020 in Pediatric and Adolescent Subjects With RPS19 Deficient Diamond-Blackfan Anemia	PHASE1	RECRUITING
Mobilization of CD34+ Peripheral Blood Stem Cells in Patients With Diamond Blackfan Anemia Syndrome (DBAS)	nan	RECRUITING
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma	nan	COMPLETED
miR-155 Expression in Episodic and Chronic Migraine	nan	UNKNOWN
Personalized Medicine Program on Myelodysplastic Syndromes: Characterization of the Patient's Genome for Clinical Decision Making and Systematic Collection of Real World Data to Improve Quality of Health Care	nan	COMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia	nan	NOT_YET_RECRUITING
Trichomonas Vaginalis Genotyping in Upper Egypt	nan	UNKNOWN
Clinical Study of Muenke Syndrome (FGFR3-Related Craniosynostosis)	nan	COMPLETED
Cytomegalovirus (CMV) MicroRNA Expression in Vivo and Immune Evasion Correlates	nan	COMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Effect of Branched Chain Amino Acids on Muscle	nan	COMPLETED
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact	nan	UNKNOWN
Role of RPL8 Protein Alterations in High-grade Serous Ovarian Carcinoma	nan	RECRUITING
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress	nan	WITHDRAWN
Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models	nan	COMPLETED
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML)	nan	COMPLETED
Positional Cloning of the Gene(s) Responsible for Alagille Syndrome	nan	COMPLETED
NFC Changes in SLE Patients and Its Correlation With Anti-U1RNPAntibodies and Disease Activity	nan	UNKNOWN
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis	nan	COMPLETED
Natural History and Genetic Studies of Usher Syndrome	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a RPS23 binder may also engage these)

Protein	Name	Similarity
P62268	—	1.000	P62268 →
G1SZ47	—	1.000	G1SZ47 →
Q3T199	—	1.000	Q3T199 →
P62267	—	1.000	P62267 →
P62298	—	0.997	P62298 →
Q6SA96	—	0.995	Q6SA96 →
Q90YQ1	—	0.983	Q90YQ1 →
Q86FP7	—	0.969	Q86FP7 →
Q9DFR4	—	0.965	Q9DFR4 →
Q9GRJ3	—	0.960	Q9GRJ3 →
Q8I7D5	—	0.940	Q8I7D5 →
Q8T3U2	—	0.936	Q8T3U2 →
Q6EV23	—	0.932	Q6EV23 →
P62246	—	0.930	P62246 →
G1TG89	—	0.930	G1TG89 →
Q962Q7	—	0.930	Q962Q7 →
Q589A4	—	0.929	Q589A4 →
Q3BAH4	—	0.928	Q3BAH4 →
Q2MIE1	—	0.928	Q2MIE1 →
A4GGF5	—	0.927	A4GGF5 →
A0A381	—	0.926	A0A381 →
Q76I82	—	0.926	Q76I82 →
O63057	—	0.926	O63057 →
G1TU13	—	0.926	G1TU13 →
P04644	—	0.926	P04644 →
Q09WV9	—	0.926	Q09WV9 →
P62245	—	0.926	P62245 →
A5PK63	—	0.925	A5PK63 →
RPS17	Small ribosomal subunit protein eS17	0.925	landscape →
A4QKN8	—	0.925	A4QKN8 →