RTF1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to RTF1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Management of Retinitis Pigmentosa Via Combination of Wharton's Jelly-derived Mesenchymal Stem Cells and Magnovision	PHASE3	COMPLETED
Treatment of Refractory Diamond-Blackfan Anemia With Eltrombopag	PHASE1/PHASE2	COMPLETED
Treatment of Chronic Delta Hepatitis With Lonafarnib and Ritonavir	PHASE2	COMPLETED
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS	PHASE2	COMPLETED
A Phase I Trial of SHR3162 in Subjects With Advanced Solid Tumors	PHASE1	COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck	PHASE1	COMPLETED
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome	PHASE1	COMPLETED
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load	PHASE1	COMPLETED
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis	nan	COMPLETED
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Telomeres Length in Israeli Fibrotic ILD Patients	nan	ENROLLING_BY_INVITATION
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma	nan	COMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics	nan	UNKNOWN
Diagnosis and Phenotype Characterisation Using Genomics in Patients With Inherited Bone Marrow Failure (IBMDx Study)	nan	RECRUITING
Telomere and Telomerase	nan	WITHDRAWN
NCF Gene & TNFSF4 in SLE Patients	nan	UNKNOWN
Collection of Blood Samples for DNA in Motor Neuron Disease	nan	COMPLETED
Gymnema Sylvestre vs Berberine in Obesity Gene Expression of Adipokines	nan	COMPLETED
New Genes Involved in Molecular Etiology of Rett Syndrome Through DNA Microarray Comparative Genomic Hybridization	nan	COMPLETED
Spironolactone and XPB-1 Integrity in the TFIIH Complex	nan	ENROLLING_BY_INVITATION
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia	nan	UNKNOWN
Transcriptional Responses as an Indicator of Individualised Responses to Radiation Effects (RTGene 2)	nan	ACTIVE_NOT_RECRUITING
Genetic Investigation of Cancer Predisposition	nan	NOT_YET_RECRUITING
Chronic Cough and CANVAS (Cerebellar Ataxia With Neuropathy and Bilateral Vestibular Areflexia Syndrome)	nan	COMPLETED
Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models	nan	COMPLETED
Genetics of Familial and Sporadic ALS	nan	COMPLETED
Diagnosis of Inflammatory Bowel Disease	nan	NOT_YET_RECRUITING
X-Chromosome Inactivation Status and Premature Ovarian Failure	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a RTF1 binder may also engage these)

Protein	Name	Similarity
Q5RAD5	—	1.000	Q5RAD5 →
A2AQ19	—	1.000	A2AQ19 →
SAP30BP	SAP30-binding protein	0.981	landscape →
GTF2F1	General transcription factor IIF subunit 1	0.981	landscape →
Q5EA53	—	0.979	Q5EA53 →
Q53F19	—	0.978	Q53F19 →
Q9BWU0	—	0.978	Q9BWU0 →
Q3THK3	—	0.978	Q3THK3 →
Q6PII3	—	0.977	Q6PII3 →
Q8CFC7	—	0.976	Q8CFC7 →
Q4ADK7	—	0.976	Q4ADK7 →
Q02614	—	0.976	Q02614 →
Q9DBF7	—	0.976	Q9DBF7 →
PRPF3	U4/U6 small nuclear ribonucleoprotein Prp3	0.976	landscape →
Q1RMM1	—	0.976	Q1RMM1 →
P49140	—	0.975	P49140 →
Q6U6G5	—	0.975	Q6U6G5 →
Q9Z315	—	0.975	Q9Z315 →
Q5ZM19	—	0.975	Q5ZM19 →
Q91WE2	—	0.975	Q91WE2 →
D3ZTQ1	—	0.975	D3ZTQ1 →
O43290	—	0.975	O43290 →
Q5HZB6	—	0.975	Q5HZB6 →
Q5XG50	—	0.975	Q5XG50 →
Q3UJB0	—	0.974	Q3UJB0 →
Q96EY4	—	0.974	Q96EY4 →
Q6AY96	—	0.974	Q6AY96 →
O75391	—	0.974	O75391 →
XPA	DNA repair protein complementing XP-A cells	0.974	landscape →
Q8WU90	—	0.974	Q8WU90 →