RUVBL2

RuvB-like 2 · Q9Y230 · RUVBL2 on Sugi Atlas →

27 patent compounds predicted against RUVBL2, 23 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL902339 SCHEMBL902339 0.59 1/20
SCHEMBL15274740 SCHEMBL15274740 0.57 1/20
SCHEMBL4725657 SCHEMBL4725657 0.52 1/20
SCHEMBL4935332 SCHEMBL4935332 0.52 1/20
SCHEMBL4940751 SCHEMBL4940751 0.51 1/20
SCHEMBL15262379 SCHEMBL15262379 0.51 1/20
SCHEMBL29748613 SCHEMBL29748613 0.51 1/20
SCHEMBL902537 SCHEMBL902537 0.51 1/20
SCHEMBL902549 SCHEMBL902549 0.50 1/20
SCHEMBL902831 SCHEMBL902831 0.50 1/20
SCHEMBL902315 SCHEMBL902315 0.49 1/20
SCHEMBL4936715 SCHEMBL4936715 0.48 1/20
SCHEMBL17616098 SCHEMBL17616098 0.48 1/20
SCHEMBL15262398 SCHEMBL15262398 0.47 1/20
SCHEMBL15277552 SCHEMBL15277552 0.47 1/20
SCHEMBL21159309 SCHEMBL21159309 0.46 1/20
SCHEMBL901731 SCHEMBL901731 0.45 1/20
SCHEMBL17616166 SCHEMBL17616166 0.45 1/20
SCHEMBL902610 SCHEMBL902610 0.43 1/20
SCHEMBL26003171 SCHEMBL26003171 0.42 1/20

Clinical trials — most relevant to RUVBL2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Management of Retinitis Pigmentosa Via Combination of Wharton's Jelly-derived Mesenchymal Stem Cells and Magnovision PHASE3COMPLETED
Histocompatibility Leukocyte Antigen (HLA)-A*0201 Restricted Peptide Vaccine Therapy in Patients With Gastric Cancer PHASE1/PHASE2COMPLETED
Histocompatibility Leukocyte Antigen (HLA)-A*0201 Restricted Peptide Vaccine Therapy in Patients With Esophageal Cancer PHASE1/PHASE2COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
New Biomarkers for Diagnosis and Follow-up of Patients With LRBA or CTLA4 Deficiencies nanUNKNOWN
Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH) nanRECRUITING
The Role of FGL2-FcgammaRIIB Inhibitory Pathway in Human Viral Hepatitis nanCOMPLETED
Exome Analysis in Hearing Impaired Patients nanUNKNOWN
Genetic Investigation of Cancer Predisposition nanNOT_YET_RECRUITING
Genetic Basis of Non Syndromic Congenital Diaphragmatic Hernia nanCOMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Study of a Candidate Gene Involved in Goldenhar Syndrome. nanCOMPLETED
Studying Tissue Samples From Patients With Stage II Colon Cancer Treated on Clinical Trial CLB-9581 nanCOMPLETED
Epidemiologic, Clinical and Molecular Characteristics of Patients With Acute Respiratory Failure Affected by 2019-NCOV. nanUNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
New Genes Involved in Molecular Etiology of Rett Syndrome Through DNA Microarray Comparative Genomic Hybridization nanCOMPLETED
Dilated Cardiomyopathy-Cardiac Magnetic Resonance (DCM-CMR) Ancillary Study nanACTIVE_NOT_RECRUITING
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS nanRECRUITING
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma nanCOMPLETED
Diagnosis of Inflammatory Bowel Disease nanNOT_YET_RECRUITING
New Strategies of Genetic Study of Patients With Oculocutaneous Albinism nanCOMPLETED
A Family Study of Copy Number Variations in Patients With Autism Spectrum Disorder nanCOMPLETED
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip nanCOMPLETED
Genetic Variants Associated With Adolescent Suicide Attempts nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a RUVBL2 binder may also engage these)

ProteinNameSimilarity
Q2TBU9 1.000 Q2TBU9 →
Q9WTM5 1.000 Q9WTM5 →
Q9DE27 1.000 Q9DE27 →
Q4P6N7 1.000 Q4P6N7 →
Q755G5 1.000 Q755G5 →
Q5AGZ9 1.000 Q5AGZ9 →
Q5BGK3 1.000 Q5BGK3 →
Q6C3X6 1.000 Q6C3X6 →
Q873C7 1.000 Q873C7 →
Q4WKH9 0.999 Q4WKH9 →
Q6CT29 0.999 Q6CT29 →
O94692 0.998 O94692 →
P0CR29 0.998 P0CR29 →
P0CR28 0.998 P0CR28 →
Q12464 0.998 Q12464 →
Q6FSF1 0.998 Q6FSF1 →
P83571 0.996 P83571 →
Q9VH07 0.996 Q9VH07 →
Q4I948 0.996 Q4I948 →
Q16TA2 0.996 Q16TA2 →
Q0IFL2 0.995 Q0IFL2 →
Q6CB52 0.995 Q6CB52 →
Q6CQA9 0.995 Q6CQA9 →
Q5BBV9 0.995 Q5BBV9 →
Q8WZS3 0.995 Q8WZS3 →
Q9V3K3 0.994 Q9V3K3 →
Q4ICA8 0.994 Q4ICA8 →
Q03940 0.994 Q03940 →
Q750R1 0.994 Q750R1 →
Q9GZH2 0.993 Q9GZH2 →