Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TYK2 | P29597 | 6/20 | 0.49 |
| ▸ | RUVBL1 | Q9Y265 | 2/20 | 0.45 |
| ▸ | RUVBL2 | Q9Y230 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | SPR | P35270 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17616106 | 0.81 | ALDH1A1 (0.53) | HSD17B10ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL4782268 | 0.75 | MAPT (0.70) | HSD17B10ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL22957953 | 0.74 | LMNA (0.44) | HSD17B10ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL902473 | 0.74 | HSD17B10 (0.57) | HSD17B10ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL17616098 | 0.73 | ALDH1A1 (0.67) | HSD17B10ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL22680752 | 0.73 | LMNA (0.53) | HSD17B10ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL22957965 | 0.73 | ALDH1A1 (0.51) | HSD17B10ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL17616095 | 0.71 | LMNA (0.72) | HSD17B10ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL4940751 | 0.70 | HSD17B10 (0.60) | HSD17B10ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL2464153 | 0.69 | ALDH1A1 (0.80) | HSD17B10ALDH1A1KDM4ETSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10912836-B2 | Synthetic antibody mimetic compounds (SyAMs) targeting cancer, especially prostate cancer | YALE UNIVERSITY (US) | 2021-02-09 | — | — | US | disclosed |
| EP-2991677-B1 | SYNTHETIC ANTIBODY MIMETIC COMPOUNDS (SYAMS) TARGETING CANCER, ESPECIALLY PROSTATE CANCER | UNIV YALE (US) | 2020-07-15 | — | — | EP | disclosed |
| US-20190209696-A1 | SYNTHETIC ANTIBODY MIMETIC COMPOUNDS (SYAMS) TARGETING CANCER, ESPECIALLY PROSTATE CANCER | UNIV YALE (US) | 2019-07-11 | — | — | US | disclosed |
| US-20160082112-A1 | SYNTHETIC ANTIBODY MIMETIC COMPOUNDS (SYAMS) TARGETING CANCER, ESPECIALLY PROSTATE CANCER | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10912836-B2 | Synthetic antibody mimetic compounds (SyAMs) targeting cancer, especially prostate cancer | CD47, FCGR1A, FCGR2A | HSD17B10 4810/4885ALDH1A1 4223/4885KDM4E 1643/4885 |
| US-20160082112-A1 | SYNTHETIC ANTIBODY MIMETIC COMPOUNDS (SYAMS) TARGETING CANCER, ESPECIALLY PROSTATE CANCER | CD47, FCGR1A, FCGR2A | HSD17B10 4789/4885ALDH1A1 3701/4885KDM4E 2155/4885 |
| US-20190209696-A1 | SYNTHETIC ANTIBODY MIMETIC COMPOUNDS (SYAMS) TARGETING CANCER, ESPECIALLY PROSTATE CANCER | CD47, FCGR1A, FCGR2A | HSD17B10 4810/4885ALDH1A1 4223/4885KDM4E 1643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.