SAAL1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to SAAL1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effect of Empagliflozin on Podocyte Specific Proteins in African American Veterans With NDKD	PHASE4	RECRUITING
Role of Finerenone in African American Veterans With Diabetic Kidney Disease	PHASE4	NOT_YET_RECRUITING
Oral Versus Patch Hormonal Contraceptive Effects on Metabolism, Clotting, Inflammatory Factors and Vascular Reactivity	PHASE2	UNKNOWN
Danazol for Genetic Bone Marrow and Lung Disorders	PHASE1/PHASE2	COMPLETED
Three Immunosuppressive Treatment Regimens for Severe Aplastic Anemia	PHASE2	COMPLETED
Comparing Therapies for the Treatment of Severe Aplastic Anemia	PHASE2	COMPLETED
Cyclophosphamide Plus Cyclosporine in Treatment-Naive Severe Aplastic Anemia	PHASE1/PHASE2	COMPLETED
Treatment of AA Amyloidosis	PHASE1	COMPLETED
The Association of SAA With Apolipoprotein B Affects Cardiovascular Risk	nan	COMPLETED
Progression of Renal Amyloidosis of FMF and Relation to Serum SAA Level	nan	UNKNOWN
Relation Between Inflammatory Responses and Sequelae of Pediatric Corrosive Ingestion Cases in Assiut	nan	NOT_YET_RECRUITING
Chronic Kidney Disease : Role of Biological Factors and Apolipoprotein L1 Encoding Gene (APOL1)	nan	COMPLETED
Impact of Antiretroviral Therapy on Cardiac Biomarkers	nan	COMPLETED
APOL1 Genetic Testing in African Americans	nan	RECRUITING
PL_GNT01_ISR_Grant 53234273	nan	UNKNOWN
Retrospective Study of Patients With Severe Aplastic Anemia Who Developed High Risk Clonal Evolution With Chromosome 7 Abnormalities After Immunosuppressive Therapy	nan	COMPLETED
Observational Study of Sepsis and Pneumonia to Develop Diagnostic Tests	nan	UNKNOWN
Inflammatory Genomics in Human Carotid Artery Disease	nan	COMPLETED
The Underlying Mechanisms For S. Aureus Infection And Colonization Of Skin in People With Atopic Dermatitis With And Without Eczema Herpeticum (MRSA)	nan	COMPLETED
INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery	nan	COMPLETED
Aging, Lifestyle and Inflammation in Veterans Exercising	nan	COMPLETED
Predictive Markers of the Course of Covid-19 Based on Biomarker Serum Amyloid A (SAA) and Genetic Markers	nan	ACTIVE_NOT_RECRUITING
Promoting Diagnosis and Management of AL in Italy (ProDigALIty)	nan	RECRUITING
Genetic Testing to Understand and Address Renal Disease Disparities Across the United States	nan	COMPLETED
Evaluation of APOL1 Gene Variants in Kidney Donors and Their Impact on Long-term Renal Function in Donors and Recipients	nan	UNKNOWN
Study of the Effect of Innate on the Inflammatory Response to Endotoxin	nan	RECRUITING
Biomarkers in Pediatric Inflammatory Rheumatic Diseases	nan	COMPLETED
A-protein Levels in Adult and Pediatric Brain Tumor Patients	nan	COMPLETED
Functional Genomic Influences on Disease Progression and Outcome in Sepsis	nan	UNKNOWN
N\L Ratio Versus L\A Ratio as a Predictor of Morbidity and Mortality in Sepsis and Septic Shock	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a SAAL1 binder may also engage these)

Protein	Name	Similarity
Q9D2C2	—	0.996	Q9D2C2 →
Q6NVK9	—	0.989	Q6NVK9 →
Q803M5	—	0.987	Q803M5 →
Q4R4Y2	—	0.986	Q4R4Y2 →
A8C756	—	0.984	A8C756 →
Q9C0B7	—	0.981	Q9C0B7 →
A8C754	—	0.981	A8C754 →
ATXN10	Ataxin-10	0.981	landscape →
Q6YHU6	—	0.980	Q6YHU6 →
Q6DCP5	—	0.980	Q6DCP5 →
B1AY13	—	0.979	B1AY13 →
Q8NEN0	—	0.978	Q8NEN0 →
Q8BW70	—	0.978	Q8BW70 →
Q6ZS81	—	0.978	Q6ZS81 →
USP24	Ubiquitin carboxyl-terminal hydrolase 24	0.978	landscape →
TTI1	TELO2-interacting protein 1 homolog	0.978	landscape →
P0C6R2	—	0.978	P0C6R2 →
Q2TBW0	—	0.978	Q2TBW0 →
O17482	—	0.977	O17482 →
Q9BPX3	—	0.977	Q9BPX3 →
Q5RE06	—	0.977	Q5RE06 →
Q9YHB5	—	0.977	Q9YHB5 →
P28658	—	0.977	P28658 →
Q8N3F0	—	0.977	Q8N3F0 →
Q6AZT7	—	0.977	Q6AZT7 →
Q95LY5	—	0.977	Q95LY5 →
Q5R9R1	—	0.976	Q5R9R1 →
O75800	—	0.976	O75800 →
Q6PIY5	—	0.976	Q6PIY5 →
A8C752	—	0.976	A8C752 →