Sugi Predict

Sugi Predict / Targets / SEC62

SEC62

Translocation protein SEC62 · Q99442 · SEC62 on Sugi Atlas →

0 patent compounds predicted against SEC62, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SEC62 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Evaluating Efficacy of Tivozanib (AV-951) in Biliary Tract Cancers PHASE1/PHASE2RECRUITING
CHED - Congenital Hereditary Endothelial Dystrophy: New Paradigm Shift in Therapy Using Topical Eye Drops PHASE2UNKNOWN
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy PHASE2COMPLETED
A Phase Ib Study to Assess Safety and Efficacy of Oral Icaritin in Advanced Solid Tumors PHASE1COMPLETED
Phase I Study of Novel Estrogen Receptor(ER) a36 Modifier Icaritin in Advanced Breast Cancer Patients PHASE1UNKNOWN
Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors PHASE1COMPLETED
A Phase I Study of Pyrimethamine in Patients With GM2 Gangliosidosis PHASE1WITHDRAWN
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
Bristol-Myers Squibb Dasatinib Src Inhibition in Endometrial Cancer EARLY_PHASE1COMPLETED
Quantification of GADD34 Expression in RA nanCOMPLETED
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
PET/CT Scans Using the Tracer 11C-Csar, a Bile Acid Analog, to Depict and Visualize Changes in the Hepatobiliary System in Patients With Primary Biliary Cholangitis Before and After Treatment. nanACTIVE_NOT_RECRUITING
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide nanRECRUITING
Hydroxychloroquin (HCQ) in chILD of Genetic Defect nanCOMPLETED
Characterization of the Pharmacokinetics of Oral Selenium Compounds in Humans Before and Following Supplementation nanCOMPLETED
Surfactant Derived Protocol in Heart Failure nanCOMPLETED
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Evaluation of CEMIP in Pancreatic Cancer nanUNKNOWN
Preliminary Study for Identification of Calcium-Binding Proteins in the Serum in Various Metabolic Bone Disorders nanUNKNOWN
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
A Clinical Study on the Efficacy and Safety of Methotrexate (MTX) or Thiotepa (for MTX Intolerance) or Temozolomide (TMZ) Combined With Orelabrutinib and Selinexor in Relapsed/Refractory Primary or Secondary Central Nervous System Lymphoma（SELINA） nanRECRUITING
Transcripts with Retained H/ACA Box SnoRNA Sequences As Biomarkers for Estrogen Dependence in Lum-B Breast Carcinomas nanACTIVE_NOT_RECRUITING
Genetic Variation in TRAF3IP2 (rs13190932) nanRECRUITING
The Relation of Microtubule-Associated Protein 2 and Cell Migration nanUNKNOWN
Identification of New Biomarkers of Insulin Resistance nanACTIVE_NOT_RECRUITING
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress nanWITHDRAWN
Role of the Nuclear Pore Component RANBP2 in Inflammatory Responses to Viral Infections nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SEC62 binder may also engage these)

ProteinNameSimilarity
Q8BU14 — 1.000 Q8BU14 →
Q5R4Q3 — 1.000 Q5R4Q3 →
Q5F3A1 — 1.000 Q5F3A1 →
A0A286Y9D1 — 0.991 A0A286Y9D1 →
EIF5B Eukaryotic translation initiation factor 5B 0.989 landscape →
Q5RDE1 — 0.989 Q5RDE1 →
Q6DD45 — 0.989 Q6DD45 →
U2SURP U2 snRNP-associated SURP motif-containing protein 0.988 landscape →
B2GUV7 — 0.988 B2GUV7 →
Q9NLA3 — 0.988 Q9NLA3 →
P52194 — 0.988 P52194 →
Q54RC3 — 0.987 Q54RC3 →
Q9VJY8 — 0.987 Q9VJY8 →
Q00313 — 0.987 Q00313 →
Q9WUL0 — 0.987 Q9WUL0 →
Q9DDT2 — 0.987 Q9DDT2 →
P35611 — 0.986 P35611 →
Q20448 — 0.986 Q20448 →
Q3T160 — 0.986 Q3T160 →
P16039 — 0.986 P16039 →
Q07050 — 0.986 Q07050 →
Q8CCG4 — 0.986 Q8CCG4 →
Q8BMD7 — 0.986 Q8BMD7 →
Q8R0A7 — 0.986 Q8R0A7 →
Q8CDA1 — 0.986 Q8CDA1 →
Q95KF9 — 0.986 Q95KF9 →
Q9D8Y8 — 0.986 Q9D8Y8 →
G5EEM9 — 0.986 G5EEM9 →
LARP1 La-related protein 1 0.986 landscape →
Q9SSE9 — 0.986 Q9SSE9 →