SEPTIN9 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Baricitinib (SCHEMBL871150)	1.00	1/20
Tandutinib (SCHEMBL927974)	1.00	1/20
Tandutinib (SCHEMBL2478362)	0.98	1/20
SCHEMBL13330466	0.98	1/20
Tandutinib (SCHEMBL2496722)	0.93	1/20
SCHEMBL13330462	0.93	1/20
Baricitinib (SCHEMBL871037)	0.92	1/20
Baricitinib (SCHEMBL1396340)	0.92	1/20
SCHEMBL872210	0.90	1/20
SCHEMBL13524739	0.89	1/20
SCHEMBL13529590	0.88	1/20
SCHEMBL872132	0.87	1/20
SCHEMBL317630	0.86	1/20
SCHEMBL13330482	0.86	1/20
SCHEMBL2365404	0.86	1/20
Baricitinib (SCHEMBL871421)	0.86	1/20
SCHEMBL871116	0.85	1/20
SCHEMBL13330479	0.85	1/20
SCHEMBL13330509	0.85	1/20
SCHEMBL12694513	0.83	1/20

Clinical trials — most relevant to SEPTIN9 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phenoxybenzamine Versus Doxazosin in PCC Patients	PHASE4	COMPLETED
Treatment With HMG-COA Reductase Inhibitor of Growth and Bone Abnormalities in Children With Noonan Syndrome	PHASE3	COMPLETED
HCCBloodTest for Detection of Hepatocellular Carcinoma (HCC)	nan	COMPLETED
Assessing the Effect of a Blood-based Colorectal Cancer Screening Test on Screening Adherence and Colonoscopy Completion	nan	COMPLETED
Circulating Cell-free DNA-based Epigenetic Biomarker mSEPT9 for Hepatocellular Carcinoma Detection in Cirrhosis	nan	COMPLETED
Addressing Colorectal Cancer in South Florida Firefighters	nan	COMPLETED
Understanding Patient Preference on Colorectal Cancer Screening Options-PSU	nan	COMPLETED
Dissect Assembly Rules of SPET12 Complex in the Mammalian Sperm	nan	COMPLETED
Diagnostic Potential of Hypermethylated DNA in Colorectal Cancer	nan	UNKNOWN
KLHL14 Expression as Predicting Factor of Invasiveness in pitNET	nan	COMPLETED
Exploratory Study of Rectal Mucus for Diagnosing Disease	nan	COMPLETED
Identification of New Colorectal Cancer Genes	nan	COMPLETED
Ohio Colorectal Cancer Prevention Initiative	nan	COMPLETED
Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s)	nan	COMPLETED
Chromosome 9 P Minus Syndrome	nan	RECRUITING
mSEPT9 Biomarker for Predicting Hepatocellular Carcinoma Occurrence in Patients With Cirrhosis	nan	RECRUITING
Genetic Identification (ID) of Segmental Dysplastic Nevi	nan	WITHDRAWN
The 3q29 Deletion and 3q29 Duplication: Architecture of Behavioral Phenotypes	nan	RECRUITING
Structural and Functional Connectivity in Autism Spectrum Disorders	nan	COMPLETED
Developing Genetic Education for Smoking Cessation	nan	COMPLETED
A Prospective Study of Molecular Detection of Salvageable Early Recurrent Nasopharyngeal Carcinoma After Radiotherapy	nan	COMPLETED
Human MATER and Idiopathic Infertility	nan	COMPLETED
Epigenetic Factors of Colorectal Adenoma in Korean	nan	NOT_YET_RECRUITING
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact	nan	UNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus	nan	COMPLETED
ASO Treatment for Syndromic Craniosynostoses	nan	NOT_YET_RECRUITING
RNA Assays for Endometriosis Detection and Diagnosis	nan	ENROLLING_BY_INVITATION
Natural History Study of Mitochondrial Myopathy	nan	RECRUITING
Prospective Study of Molecular Predictors of Survival in Myelodysplastic Syndromes	nan	COMPLETED
Pancreatic Intraepithelial Neoplasia (PanIN) and the Association With Recurrence of Pancreatic Adenocarcinoma	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a SEPTIN9 binder may also engage these)

Protein	Name	Similarity
Q80UG5	—	1.000	Q80UG5 →
Q9QZR6	—	1.000	Q9QZR6 →
J9VW97	—	0.990	J9VW97 →
SEPTIN8	Septin-8	0.990	landscape →
O43078	—	0.990	O43078 →
A5E032	—	0.989	A5E032 →
Q6E3D4	—	0.989	Q6E3D4 →
Q6CAP3	—	0.989	Q6CAP3 →
O43236	—	0.989	O43236 →
Q2UMR9	—	0.989	Q2UMR9 →
Q6AYK9	—	0.988	Q6AYK9 →
A3GEV2	—	0.988	A3GEV2 →
P0CO32	—	0.988	P0CO32 →
O60167	—	0.988	O60167 →
Q9Y7P6	—	0.988	Q9Y7P6 →
Q6C882	—	0.988	Q6C882 →
Q5AAF4	—	0.988	Q5AAF4 →
Q9Y794	—	0.988	Q9Y794 →
Q5R6R7	—	0.988	Q5R6R7 →
Q1DU03	—	0.988	Q1DU03 →
Q6C0K9	—	0.988	Q6C0K9 →
Q4WTT2	—	0.988	Q4WTT2 →
Q6CUA5	—	0.987	Q6CUA5 →
P40797	—	0.987	P40797 →
Q07657	—	0.987	Q07657 →
Q10107	—	0.987	Q10107 →
P48010	—	0.987	P48010 →
P48479	—	0.987	P48479 →
A2QHV0	—	0.987	A2QHV0 →
A1CYR9	—	0.987	A1CYR9 →