SF3A1

Splicing factor 3A subunit 1 · Q15459 · SF3A1 on Sugi Atlas →

0 patent compounds predicted against SF3A1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SF3A1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Valproate and Levocarnitine in Children With Spinal Muscular Atrophy PHASE3UNKNOWN
Enzalutamide and Cabazitaxel in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer PHASE1/PHASE2ACTIVE_NOT_RECRUITING
New Treatment Strategies and Epigenetic Biomarker for Management of Benign Prostatic Hyperplasia PHASE2RECRUITING
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Biocollection in MyeloDysplastic Syndrome (P-MDS) nanRECRUITING
Personalized Medicine Program on Myelodysplastic Syndromes: Characterization of the Patient's Genome for Clinical Decision Making and Systematic Collection of Real World Data to Improve Quality of Health Care nanCOMPLETED
Molecular Disease Profile of Hematological Malignancies nanUNKNOWN
SRSF2 Gene Mutation in Patients With t-MDS/AML nanCOMPLETED
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
Genomic Services Research Program nanRECRUITING
Mechanisms of Cell Death in Spinal Muscular Atrophy nanCOMPLETED
Patient's Derived Organoids for Drug Screening in Glioblastoma nanNOT_YET_RECRUITING
Ferroptosis Study in SF3B1-mutant Myelodysplastic Syndromes (FerMDS) nanRECRUITING
Monitoring Mutational Burden in Low Risk MDS Patients Using Sequential Peripheral Blood Samples nanRECRUITING
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Becker Muscular Dystrophy - A Natural History Study to Predict Efficacy of Exon Skipping nanUNKNOWN
Clinical Study of Spinal Muscular Atrophy nanCOMPLETED
Efficacy and Safety Study of EGCG/Tocotrienol in 18 Patients With Splicing-mutation-mediated Cystic Fibrosis (CF) nanCOMPLETED
GENOMED4ALL: Improving MDS Classification and Prognosis by AI nanUNKNOWN
Outcome Measures and Biomarkers in a Cohort of Spinal Muscular Atrophy Type III/ IV Patients nanACTIVE_NOT_RECRUITING
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia nanRECRUITING
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
SMN Circular RNAs as Potential Biomarkers for the Therapeutic Response to Nusinersen in Spinal Muscular Atrophy Patients nanUNKNOWN
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes nanUNKNOWN
Studying Gene Expression in Tissue Samples From Young Patients With Acute Myeloid Leukemia nanCOMPLETED
New Imaging Biomarkers for Muscular Diseases - Multispectral Optoacoustic Imaging in Spinal Muscular Atrophy nanCOMPLETED
Investigation of Tumor Microenvironment After CRPC Along With Before and After Neoadjuvant Therapy for Prostate Cancer nanUNKNOWN
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
Hydroxychloroquin (HCQ) in chILD of Genetic Defect nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SF3A1 binder may also engage these)

ProteinNameSimilarity
A2VDN6 1.000 A2VDN6 →
Q8K4Z5 1.000 Q8K4Z5 →
Q8RXF1 0.988 Q8RXF1 →
PRPF3 U4/U6 small nuclear ribonucleoprotein Prp3 0.984 landscape →
Q3UJB0 0.982 Q3UJB0 →
Q5ZJ85 0.982 Q5ZJ85 →
Q5R5F1 0.982 Q5R5F1 →
Q95107 0.982 Q95107 →
Q922U1 0.980 Q922U1 →
Q2KIA6 0.980 Q2KIA6 →
SAP30BP SAP30-binding protein 0.980 landscape →
O08816 0.980 O08816 →
SF3B2 Splicing factor 3B subunit 2 0.980 landscape →
SRRT Serrate RNA effector molecule homolog 0.980 landscape →
Q9P2N5 0.978 Q9P2N5 →
RBM26 RNA-binding protein 26 0.978 landscape →
Q99MR6 0.978 Q99MR6 →
Q6NZN0 0.978 Q6NZN0 →
Q2NLB0 0.978 Q2NLB0 →
A4IGK4 0.977 A4IGK4 →
Q5R539 0.977 Q5R539 →
Q6NZ18 0.976 Q6NZ18 →
Q58A65 0.976 Q58A65 →
A0JMV4 0.976 A0JMV4 →
Q02614 0.975 Q02614 →
Q2HJG8 0.975 Q2HJG8 →
A4IFB1 0.975 A4IFB1 →
Q9XHM1 0.975 Q9XHM1 →
Q69ZX6 0.975 Q69ZX6 →
D3ZTQ1 0.974 D3ZTQ1 →