Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC14A1 | Q13336 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11001442 | 0.87 | NPC1 (0.57) | SLC14A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL29912577 | 0.87 | NPC1 (0.57) | SLC14A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL16372920 | 0.77 | MAPT (0.63) | MAPTKMT2ARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL12562446 | 0.75 | SLC14A1 (0.60) | SLC14A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL12562427 | 0.73 | LIMK1 (0.77) | SLC14A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL19769162 | 0.72 | SLC14A1 (0.81) | SLC14A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL13954996 | 0.70 | MAPT (0.47) | MAPTKMT2ARAB9AMEN1KDM4E | |
| SCHEMBL9541407 | 0.70 | ALDH1A1 (0.50) | SLC14A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL19769233 | 0.70 | NPC1 (0.70) | SLC14A1MAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL10632495 | 0.70 | MAPT (0.61) | SLC14A1MAPTKMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152301-A1 | Compounds that Inhibit HIV Particle Formation | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152301-A1 | Compounds that Inhibit HIV Particle Formation | REV1, VPS51, FLOT1 | SLC14A1 4599/4885MAPT 1501/4885KMT2A 4150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.