SLC34A3

Sodium-dependent phosphate transport protein 2C · Q8N130 · SLC34A3 on Sugi Atlas →

924 patent compounds predicted against SLC34A3, 477 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL267024 SCHEMBL267024 1.00 1/20
SCHEMBL267025 SCHEMBL267025 1.00 1/20
SCHEMBL267842 SCHEMBL267842 0.80 1/20
SCHEMBL267843 SCHEMBL267843 0.80 1/20
SCHEMBL267856 SCHEMBL267856 0.80 1/20
SCHEMBL267857 SCHEMBL267857 0.80 1/20
SCHEMBL267924 SCHEMBL267924 0.79 1/20
SCHEMBL267925 SCHEMBL267925 0.79 1/20
SCHEMBL268319 SCHEMBL268319 0.78 1/20
SCHEMBL268320 SCHEMBL268320 0.78 1/20
SCHEMBL274252 SCHEMBL274252 0.78 1/20
SCHEMBL266512 SCHEMBL266512 0.76 1/20
SCHEMBL266513 SCHEMBL266513 0.76 1/20
SCHEMBL267960 SCHEMBL267960 0.76 1/20
SCHEMBL267961 SCHEMBL267961 0.76 1/20
SCHEMBL267826 SCHEMBL267826 0.75 1/20
SCHEMBL267827 SCHEMBL267827 0.75 1/20
SCHEMBL274075 SCHEMBL274075 0.75 1/20
SCHEMBL265763 SCHEMBL265763 0.73 1/20
SCHEMBL265764 SCHEMBL265764 0.73 1/20

Clinical trials — most relevant to SLC34A3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Study of the Anti-FGF23 Antibody, Burosumab, in Adults With XLH PHASE3COMPLETED
BSEP Function Rescue During Childhood Inhereditary Cholestatic Diseases PHASE2/PHASE3WITHDRAWN
A Study Comparing CO-1.01 With Gemcitabine as First Line Therapy in Patients With Metastatic Pancreatic Adenocarcinoma (LEAP) PHASE2COMPLETED
Clofarabine and Cytarabine in Treating Young Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia PHASE1/PHASE2COMPLETED
Influence of the OATP1B1 and OATP1B3 Genotype on the Hepatic Uptake of Primovist® PHASE1/PHASE2COMPLETED
Effect of, OAT3, on the Renal Secretion of Cefotaxime PHASE1COMPLETED
Healthy Combine Study PHASE1COMPLETED
Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters EARLY_PHASE1COMPLETED
Oxalate and Citrate in Humans - Response to Citrate nanRECRUITING
PET/CT Scans Using the Tracer 11C-Csar, a Bile Acid Analog, to Depict and Visualize Cholestatic Disorders in Patients with Genetic Liver Disorders and Healthy Individuals nanENROLLING_BY_INVITATION
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy nanCOMPLETED
Prevalence and Risk Factors of Nephrocalcinosis in Children at Sohag University Hospital nanUNKNOWN
Cardiovascular Effects of Empagliflozine nanUNKNOWN
Calcitonin for Treating X-linked Hypophosphatemia nanCOMPLETED
Sodium Transport: Genetics and Hypertension nanCOMPLETED
POTASSIUM-RICH SALT SUBSTITUTES IN KIDNEY TRANSPLANT RECIPIENTS nanNOT_YET_RECRUITING
Impact of Polymorphisms of OAT1, OAT3, and OCT2 on Transportation of Potential Nephrotoxic Drugs nanCOMPLETED
Epidemiology of Gout in French Polynesia nanCOMPLETED
Clinical and Genetic Analysis of Enlarged Vestibular Aqueducts nanCOMPLETED
Studying Phosphorus Metabolism nanCOMPLETED
Secondary Sclerosing Cholangitis in Critically Ill Patients nanACTIVE_NOT_RECRUITING
Gene Expression in Inflammatory Bowel Disease nanENROLLING_BY_INVITATION
Bile Acid Effects in Fetal Arrhythmia Study nanUNKNOWN
Institution of an Italian Multicenter Database of Patients Affected by Diseases of Phosphate Metabolism nanNOT_YET_RECRUITING
The Effectiveness and Safety of Calcium Carbonate in Chronic Kidney Disease With Normophosphatemia nanCOMPLETED
Renal Transporters After Renal Transplantation nanUNKNOWN
Biological Collection of Kidney Cells nanUNKNOWN
Lithium Countertransport and Blood Pressure In CARDIA and TOMHS nanCOMPLETED
Histiocytosis and Inflammatory Manifestations in Patients with H Syndrome nanRECRUITING
Genetic Regulation of Surfactant Deficiency nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SLC34A3 binder may also engage these)

ProteinNameSimilarity
Q80SU6 1.000 Q80SU6 →
Q8K4R8 0.999 Q8K4R8 →
SLC34A1 Sodium-dependent phosphate transport protein 2A 0.994 landscape →
O97704 0.991 O97704 →
Q60825 0.986 Q60825 →
Q28620 0.985 Q28620 →
Q06496 0.982 Q06496 →
B5MEV3 0.973 B5MEV3 →
D2HSA6 0.972 D2HSA6 →
Q96Q91 0.969 Q96Q91 →
Q9GKY1 0.969 Q9GKY1 →
Q863Y7 0.969 Q863Y7 →
Q4FZU9 0.969 Q4FZU9 →
Q5E9R1 0.969 Q5E9R1 →
Q9NQ40 0.969 Q9NQ40 →
Q643R3 0.968 Q643R3 →
Q658P3 0.968 Q658P3 →
SOAT2 Sterol O-acyltransferase 2 0.968 landscape →
Q9D8F3 0.967 Q9D8F3 →
Q6P5W5 0.966 Q6P5W5 →
F1NXU8 0.966 F1NXU8 →
Q9CTG6 0.966 Q9CTG6 →
Q86U10 0.965 Q86U10 →
Q8K4V2 0.965 Q8K4V2 →
Q5RKL5 0.965 Q5RKL5 →
Q9DBP0 0.964 Q9DBP0 →
O88908 0.964 O88908 →
Q9BU23 0.964 Q9BU23 →
Q8VCZ9 0.963 Q8VCZ9 →
SLC5A2 Sodium/glucose cotransporter 2 0.963 landscape →