SMC3

Structural maintenance of chromosomes protein 3 · Q9UQE7 · SMC3 on Sugi Atlas →

0 patent compounds predicted against SMC3, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SMC3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Cornelia De Lange Syndrome: Assessing Positive Effects of Lithium Treatment PHASE2/PHASE3RECRUITING
Trial of the Histone-Deacetylase Inhibitor ITF2357 Followed by Mechlorethamine in Relapsed/Refractory Hodgkin's Lymphoma PHASE1/PHASE2COMPLETED
Study of Cytolytic Viral Activation Therapy (CVAT) for Recurrent/Metastatic Nasopharyngeal Carcinoma PHASE1UNKNOWN
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome PHASE1COMPLETED
Imetelstat for Children With Refractory or Recurrent Solid Tumors and Lymphoma PHASE1WITHDRAWN
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load PHASE1COMPLETED
Proteomic-Based Profiling of Lymphomas: Chromatin Proteomics; Composition and Modification of Histone and Non-Histone Chromosomal Proteins nanCOMPLETED
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases nanNOT_YET_RECRUITING
Immunophenotyping and Xist Gene in AML nanUNKNOWN
Study of Synapsis and Recombination in Male Meiosis and the Implications in Infertility nanCOMPLETED
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
Mesenchymal Stem Cells in NPM1 Mutated Low Risk Acute Myeloid Leukemia: a Study of the Tumor Microenvironment and Its Contribution to the Outcome nanCOMPLETED
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING
The Contribution of Optical Mapping to the Characterization of Chromosomal Rearrangements in Patients With Neurodevelopmental Disorders nanRECRUITING
Impact of Weight Loss on the Human Sperm Epitranscriptome nanACTIVE_NOT_RECRUITING
Genetic of SportS Induced Endofibrotic Remodeling nanCOMPLETED
Family Blood Pressure Program - SAPPHIRe Network nanCOMPLETED
DNA Methylation and Autoimmune Thyroid Diseases nanCOMPLETED
Better Delineation of CDK13 Related Phenotype and Epigenetic Signature. nanUNKNOWN
Telomeres Length in Israeli Fibrotic ILD Patients nanENROLLING_BY_INVITATION
Impact of Ionizing Treatment on the Nuclear Structure of Human Spermatozoa. nanUNKNOWN
Initiative for Clinical Long-read Sequencing nanNOT_YET_RECRUITING
Telomeric Abnormalities in Colorectal Diseases by Fluorescent in Situ Hybridization Technique nanUNKNOWN
Chromosome 18 Clinical Research Center nanRECRUITING
The 3q29 Deletion and 3q29 Duplication: Architecture of Behavioral Phenotypes nanRECRUITING
Biological Aging Hallmarks-Guided Integrative TCM and Conventional Medicine in Post-Treatment Unexplained Female Infertility nanRECRUITING
Prenatal Cell-free DNA Screening in Pregnancies With Diverse Genetic Risk Profiles Utilizing Targeted and Whole-exome Sequencing nanNOT_YET_RECRUITING
Telomere Repair Gene Mutation in Inflammatory Bowel Disease nanCOMPLETED
Identifying Genes Involved in Abnormal Blood Pressure - Hypertension SCOR nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SMC3 binder may also engage these)

ProteinNameSimilarity
O97594 1.000 O97594 →
Q5R4K5 1.000 Q5R4K5 →
Q9CW03 1.000 Q9CW03 →
P97690 1.000 P97690 →
O93309 1.000 O93309 →
Q00737 0.998 Q00737 →
Q8CG48 0.993 Q8CG48 →
J9VL63 0.993 J9VL63 →
O42649 0.992 O42649 →
B2FDA8 0.990 B2FDA8 →
Q9C5Y4 0.989 Q9C5Y4 →
Q9FJL0 0.988 Q9FJL0 →
P50533 0.988 P50533 →
SMC2 Structural maintenance of chromosomes protein 2 0.988 landscape →
O01789 0.987 O01789 →
Q54PK4 0.987 Q54PK4 →
Q8NDV3 0.987 Q8NDV3 →
Q9SN90 0.986 Q9SN90 →
Q6Q1P4 0.985 Q6Q1P4 →
Q920F6 0.984 Q920F6 →
Q96SB8 0.984 Q96SB8 →
Q802R8 0.984 Q802R8 →
P47037 0.984 P47037 →
Q924W5 0.984 Q924W5 →
Q90988 0.983 Q90988 →
O94383 0.982 O94383 →
P38989 0.981 P38989 →
Q9LFS8 0.981 Q9LFS8 →
Q8CG47 0.981 Q8CG47 →
Q9ERA5 0.981 Q9ERA5 →