Sugi Predict

Sugi Predict / Targets / SPCS3

SPCS3

Signal peptidase complex subunit 3 · P61009 · SPCS3 on Sugi Atlas →

0 patent compounds predicted against SPCS3, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SPCS3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
D-Cycloserine for Serine Palmitoyltransferase Inhibition PHASE4COMPLETED
Effects of Botulinum Toxin Injections in Patients With Hereditary Spastic Paraplegia PHASE2/PHASE3COMPLETED
Neurobiology of a Mutation in Glycine Metabolism in Psychotic Disorders PHASE2COMPLETED
Hydroxychloroquin (HCQ) in chILD of Genetic Defect nanCOMPLETED
Surfactant Derived Protocol in Heart Failure nanCOMPLETED
Consequences of Mutations in the SPG7 Gene at the Heterozygous State nanCOMPLETED
New Genes in the Carcinogenesis of Colorectal Cancer nanUNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD) nanCOMPLETED
PCD New Gene Discovery nanCOMPLETED
National Psoriasis Foundation - Dendritic Cell-Specific Transmembrane Protein (DC-Stamp) Biomarker Study nanCOMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
Genetic Regulation of Surfactant Deficiency nanCOMPLETED
Natural History Study of Smith-Magenis Syndrome nanACTIVE_NOT_RECRUITING
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Diagnosis of Primary Ciliary Dyskinesia nanCOMPLETED
Circadian Rhythms and Sleep in Familial DSPS and ASPS nanCOMPLETED
Central and Peripheral Nervous System Changes as Markers of Disease Progression in Multiple Sclerosis nanCOMPLETED
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Hong Kong Spinocerebellar Ataxias Registry nanRECRUITING
Genetic Analysis of Hereditary Disorders of Hearing and Balance nanCOMPLETED
New Genes Involved in Molecular Etiology of Rett Syndrome Through DNA Microarray Comparative Genomic Hybridization nanCOMPLETED
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
Identification of Biomarkers Associated With Human Hepatocellular Carcinoma by SELDI nanUNKNOWN
Genetic Variants and Regulation of Specialized Pro-resolving Mediator nanRECRUITING
Autophagy Bladder Cancer nanUNKNOWN
SNAP: Measurement of the Subjective Perception of the Symptom in Hereditary Spastic Paraparesis (HSP) nanCOMPLETED
Investigation of Copy Number Variations and Genetic Variants in POI nanRECRUITING
the Role of plin5 in the Development of Nonalcoholic Fatty Liver Disease. nanUNKNOWN
Integrated Proteomic HPLC-ESI-MS Analysis of Salivary Peptides of Preterm Newborns: a Pilot Study nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SPCS3 binder may also engage these)

ProteinNameSimilarity
Q6ZWQ7 — 1.000 Q6ZWQ7 →
P61008 — 1.000 P61008 →
Q3SZU5 — 1.000 Q3SZU5 →
P28687 — 0.995 P28687 →
C0HK79 — 0.973 C0HK79 →
C0HK80 — 0.973 C0HK80 →
Q568Z4 — 0.970 Q568Z4 →
F1QR43 — 0.955 F1QR43 →
Q9VCA9 — 0.955 Q9VCA9 →
Q5M8Y1 — 0.951 Q5M8Y1 →
Q28C34 — 0.950 Q28C34 →
Q9EPS3 — 0.948 Q9EPS3 →
O94923 — 0.948 O94923 →
Q4R512 — 0.948 Q4R512 →
Q5RF53 — 0.946 Q5RF53 →
Q9CYN2 — 0.946 Q9CYN2 →
A6H7H7 — 0.945 A6H7H7 →
Q5BJI9 — 0.945 Q5BJI9 →
Q5XIK2 — 0.945 Q5XIK2 →
Q4R5B4 — 0.944 Q4R5B4 →
Q8CIF6 — 0.944 Q8CIF6 →
O18756 — 0.944 O18756 →
Q6NRD0 — 0.943 Q6NRD0 →
D3ZEH5 — 0.943 D3ZEH5 →
Q5RAY6 — 0.942 Q5RAY6 →
Q9UK99 — 0.942 Q9UK99 →
Q6P4P2 — 0.942 Q6P4P2 →
Q9P2C4 — 0.941 Q9P2C4 →
Q9CR89 — 0.941 Q9CR89 →
SPCS2 Signal peptidase complex subunit 2 0.941 landscape →