SRP19 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to SRP19 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes	PHASE4	UNKNOWN
A Trial to Learn More About an Experimental Gene Therapy Called Bidridistrogene Xeboparvovec (SRP-9003) as a Possible Treatment for Limb Girdle Muscular Dystrophy 2E/R4	PHASE3	ACTIVE_NOT_RECRUITING
Targeting Endoplasmic Reticulum Stress in Human Hypertension	PHASE1/PHASE2	RECRUITING
Mobilization of Stem Cells With G-CSF for Collection From Patients With Diamond-Blackfan Anemia	PHASE2	COMPLETED
Assessing the Safety, Tolerability, and Efficacy of APR-2020 in Pediatric and Adolescent Subjects With RPS19 Deficient Diamond-Blackfan Anemia	PHASE1	RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma	PHASE1	COMPLETED
PBA Use for Treatment of ATF6-/- Patients	EARLY_PHASE1	SUSPENDED
Evaluation of the Safety and Efficacy of BBM-D101 to Treat Patients with Duchenne Muscular Dystrophy	EARLY_PHASE1	RECRUITING
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia	nan	NOT_YET_RECRUITING
Role of Sorcin and Annexin A3 in Breast Cancer Patients	nan	UNKNOWN
Investigations Into ISCU Myopathy or Iron Sulfur Scaffold U Protein Myopathy	nan	COMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Genetic Variation in TRAF3IP2 (rs13190932)	nan	RECRUITING
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic	nan	COMPLETED
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis	nan	COMPLETED
Mechanisms of Cell Death in Spinal Muscular Atrophy	nan	COMPLETED
Testing of Micellar Casein, Blended Micellar Casein and Native Whey	nan	COMPLETED
Patient's Derived Organoids for Drug Screening in Glioblastoma	nan	NOT_YET_RECRUITING
Muscle Tissue Bank for Muscular Dystrophy	nan	COMPLETED
Quantification of GADD34 Expression in RA	nan	COMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus	nan	COMPLETED
B3 for NMD: Bench to Bedside and Back	nan	ENROLLING_BY_INVITATION
Effect of Branched Chain Amino Acids on Muscle	nan	COMPLETED
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide	nan	RECRUITING
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Study of Constitutional Platelet Disease	nan	UNKNOWN
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer	nan	UNKNOWN
Candidate Gene for Hyperferritinemia	nan	UNKNOWN
Genetic Analysis of Gray Platelet Syndrome	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a SRP19 binder may also engage these)

Protein	Name	Similarity
Q3ZBG7	—	1.000	Q3ZBG7 →
Q5RBR1	—	1.000	Q5RBR1 →
J9PAS6	—	1.000	J9PAS6 →
Q9D7A6	—	0.999	Q9D7A6 →
O61749	—	0.993	O61749 →
P49964	—	0.990	P49964 →
P49963	—	0.989	P49963 →
Q90YT7	—	0.979	Q90YT7 →
Q56JX3	—	0.979	Q56JX3 →
G1SHG0	—	0.979	G1SHG0 →
Q5RJS9	—	0.978	Q5RJS9 →
Q7TND5	—	0.977	Q7TND5 →
Q554G7	—	0.977	Q554G7 →
Q7SIA2	—	0.977	Q7SIA2 →
P05737	—	0.976	P05737 →
Q8SRC3	—	0.976	Q8SRC3 →
Q498P2	—	0.976	Q498P2 →
P0C2H8	—	0.975	P0C2H8 →
Q9U332	—	0.975	Q9U332 →
G5ECQ8	—	0.975	G5ECQ8 →
Q5RBR9	—	0.975	Q5RBR9 →
Q9H9Y2	—	0.975	Q9H9Y2 →
O65353	—	0.975	O65353 →
Q6CF35	—	0.975	Q6CF35 →
Q5R631	—	0.975	Q5R631 →
Q3AUW9	—	0.975	Q3AUW9 →
Q7U4J3	—	0.975	Q7U4J3 →
B0K020	—	0.975	B0K020 →
Q9VFJ2	—	0.975	Q9VFJ2 →
EPRS1	Bifunctional glutamate/proline--tRNA ligase	0.975	landscape →