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SRP72

Signal recognition particle subunit SRP72 · O76094 · SRP72 on Sugi Atlas →

1,844 patent compounds predicted against SRP72, 1,631 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Molibresib Molibresib (SCHEMBL1872390) 1.00 1/20
Molibresib Molibresib (SCHEMBL12671490) 1.00 1/20
Molibresib Molibresib (SCHEMBL12966358) 1.00 1/20
SCHEMBL9998851 SCHEMBL9998851 0.91 1/20
SCHEMBL14756282 SCHEMBL14756282 0.88 1/20
SCHEMBL15980874 SCHEMBL15980874 0.88 1/20
SCHEMBL12966165 SCHEMBL12966165 0.87 1/20
SCHEMBL14756215 SCHEMBL14756215 0.87 1/20
SCHEMBL14756339 SCHEMBL14756339 0.87 1/20
SCHEMBL15980861 SCHEMBL15980861 0.87 1/20
SCHEMBL9998825 SCHEMBL9998825 0.86 1/20
SCHEMBL15980893 SCHEMBL15980893 0.86 1/20
SCHEMBL15980803 SCHEMBL15980803 0.86 1/20
SCHEMBL1874116 SCHEMBL1874116 0.85 1/20
SCHEMBL12671221 SCHEMBL12671221 0.85 1/20
SCHEMBL14756021 SCHEMBL14756021 0.85 1/20
SCHEMBL14756240 SCHEMBL14756240 0.85 1/20
SCHEMBL14756287 SCHEMBL14756287 0.85 1/20
SCHEMBL14756335 SCHEMBL14756335 0.85 1/20
SCHEMBL14756409 SCHEMBL14756409 0.85 1/20

Clinical trials — most relevant to SRP72 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes PHASE4UNKNOWN
A Trial to Learn More About an Experimental Gene Therapy Called Bidridistrogene Xeboparvovec (SRP-9003) as a Possible Treatment for Limb Girdle Muscular Dystrophy 2E/R4 PHASE3ACTIVE_NOT_RECRUITING
Cardioprotective Empagliflozin for Cancer Patients Receiving Doxorubicin PHASE2/PHASE3UNKNOWN
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Cixutumumab and Temsirolimus in Treating Patients With Metastatic Prostate Cancer PHASE1/PHASE2COMPLETED
Evaluation of the Safety and Efficacy of BBM-D101 to Treat Patients with Duchenne Muscular Dystrophy EARLY_PHASE1RECRUITING
Role of Sorcin and Annexin A3 in Breast Cancer Patients nanUNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Mechanisms of Cell Death in Spinal Muscular Atrophy nanCOMPLETED
Investigations Into ISCU Myopathy or Iron Sulfur Scaffold U Protein Myopathy nanCOMPLETED
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide nanRECRUITING
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Genetic and Blood Biomarkers in Neurological and Neuromuscular Diseases nanCOMPLETED
Efficacy and Safety of Deep Cervical Lymph Node-vein Bypass Surgery in ALS Amyotrophic Lateral Sclerosis nanNOT_YET_RECRUITING
Study of Constitutional Platelet Disease nanUNKNOWN
Genetics of Familial and Sporadic ALS nanCOMPLETED
Genetic Linkage Studies of Stuttering nanCOMPLETED
Study of ALS Reversals 2: Genetic Analyses nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma nanCOMPLETED
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Precision Diagnosis and Therapy for Rare Diseases by Interpreting Non-coding Genomes nanRECRUITING
Pleiotropy and Mechanism of Peripheral Nerve Related Genes in the Progression of Amyotrophic Lateral Sclerosis nanUNKNOWN
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others nanRECRUITING
Clinical Outcome Study for Dysferlinopathy nanUNKNOWN
Shwachman Diamond Syndrome Registry and Study nanRECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Transcripts with Retained H/ACA Box SnoRNA Sequences As Biomarkers for Estrogen Dependence in Lum-B Breast Carcinomas nanACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a SRP72 binder may also engage these)

ProteinNameSimilarity
P33731 — 1.000 P33731 →
P49965 — 0.995 P49965 →
O42668 — 0.995 O42668 →
Q8LGU6 — 0.994 Q8LGU6 →
Q0IG18 — 0.992 Q0IG18 →
P89105 — 0.992 P89105 →
Q6INC1 — 0.992 Q6INC1 →
P91240 — 0.992 P91240 →
Q8I7G4 — 0.992 Q8I7G4 →
Q5U2N8 — 0.992 Q5U2N8 →
Q7Q373 — 0.990 Q7Q373 →
Q03560 — 0.990 Q03560 →
Q06AN9 — 0.990 Q06AN9 →
Q9VDQ7 — 0.990 Q9VDQ7 →
A2A6Q5 — 0.990 A2A6Q5 →
Q8SYD0 — 0.990 Q8SYD0 →
Q3UPL0 — 0.989 Q3UPL0 →
Q13099 — 0.989 Q13099 →
A6H7B5 — 0.989 A6H7B5 →
Q294E0 — 0.989 Q294E0 →
Q8SYG2 — 0.989 Q8SYG2 →
Q20255 — 0.988 Q20255 →
Q32PZ3 — 0.988 Q32PZ3 →
Q8C0S4 — 0.988 Q8C0S4 →
B4KDK5 — 0.988 B4KDK5 →
Q8BS45 — 0.988 Q8BS45 →
Q9V431 — 0.988 Q9V431 →
Q7SYD5 — 0.988 Q7SYD5 →
A8XBR9 — 0.988 A8XBR9 →
Q5TYV4 — 0.988 Q5TYV4 →