STIM2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL12274132	1.00	2/20
SCHEMBL19692208	1.00	2/20
SCHEMBL19692266	0.88	2/20
SCHEMBL19692296	0.86	2/20
SCHEMBL19692302	0.86	2/20
SCHEMBL19706471	0.84	2/20
SCHEMBL19692261	0.83	2/20
SCHEMBL19692185	0.82	2/20
SCHEMBL19692294	0.82	2/20
SCHEMBL19692216	0.81	2/20
SCHEMBL19692376	0.80	2/20
SCHEMBL19692335	0.79	2/20
SCHEMBL19692308	0.77	2/20
SCHEMBL19692327	0.77	2/20
SCHEMBL19706473	0.77	2/20
SCHEMBL21407058	0.74	2/20
SCHEMBL19692295	0.73	2/20
SCHEMBL19692301	0.73	2/20
SCHEMBL19706442	0.73	2/20
SCHEMBL19706475	0.73	2/20

Clinical trials — most relevant to STIM2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
The Effect of Ramipril in Suppressing ST2 Expression in Rheumatic Mitral Stenosis Patients	PHASE3	UNKNOWN
Can Calcium Ionophore Application Enhance the ICSI Outcomes in Severe Male Factor Infertility?	PHASE2/PHASE3	UNKNOWN
Role of Colchicine as Anti-Inflammatory Therapy in HFpEF	PHASE3	ACTIVE_NOT_RECRUITING
The Re-Prosper HF Study	PHASE2/PHASE3	COMPLETED
Sodium Citrate in Smell Retraining for People With Post-COVID-19 Olfactory Dysfunction	PHASE2	ACTIVE_NOT_RECRUITING
Lovaza's Effect on the Activation of Platelets	PHASE2	COMPLETED
Pembrolizumab Plus Enfortumab Vedotin in Collecting Duct and Renal Medullary Carcinoma	PHASE2	RECRUITING
Pembrolizumab and Induction Chemotherapy in Head and Neck Squamous Cell Carcinoma (PICH Study)	PHASE1/PHASE2	WITHDRAWN
Pembrolizumab (MK-3475) in MM Patients With Residual Disease	PHASE2	COMPLETED
Serum sST2/ miR-223 as a Dual Biomarker for Disease Activity & Clinical Efficacy of SLIT in HDM-Induced Allergic Rhinitis	PHASE1	COMPLETED
Bioequivalence Study of Tacrolimus in Healthy Volunteers	PHASE1	COMPLETED
Study of STIM1 Membrane Expression	nan	RECRUITING
Soluble ST2 in Patients With Heart Failure	nan	NOT_YET_RECRUITING
Novel Biomarkers in Inflammatory Bowel Disease	nan	COMPLETED
Assessment of Serum CD25 Level in Systemic Sclerosis Patients with or Without Interstitial Lung Disease (ILD)	nan	NOT_YET_RECRUITING
Genetic Determinants of Sudden Cardiac Death	nan	COMPLETED
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study)	nan	COMPLETED
How Secreted-embryo-derived Trypsin Initiates, Maintains and Terminates Ca2+ Signals in Uterine Epithelial Cells	nan	COMPLETED
Uterine Cavity Assessment and Endometrial Gene Expression in Tamoxifen Treated Breast Cancer Patients	nan	UNKNOWN
Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) in Ischaemic, Inflammatory and Takotsubo Cardiomyopathy (MEMORY)	nan	COMPLETED
Understanding Immunotherapy Resistance Mechanisms in Advanced Melanoma	nan	COMPLETED
Biometric and Biological Data for Diagnosis and Therapy of Pain Patients	nan	UNKNOWN
Microneurographic Assessment of Peripheral Nerves in Healthy Volunteers and Individuals With Sensory Dysfunction Caused by Inherited Mutations in the PIEZO2 Gene	nan	RECRUITING
Searching for Novel Therapeutic Approaches in Migraine Patients Resistant to Treatments	nan	RECRUITING
Evaluation of Plasma Sphingosine-1-Phosphate as A Diagnostic and Prognostic Biomarkers of Community-Acquired Pneumonia	nan	UNKNOWN
Effects of Photobiomodulation on the Innate Immune System of Neonates and Infants With Bronchiolitis	nan	UNKNOWN
Development of Therapeutic Approaches Modulating Molecular Targets Implicated on Cancer Stem Cell-related Aggressiveness	nan	UNKNOWN
C-X-C Chemokine Receptor 4 in Chronic Lymphocytic Leukemia	nan	UNKNOWN
Effect of Ivabradine on Levcromakalim-Induced Symptoms in Individuals With Migraine Without Aura (ILIM)	nan	COMPLETED
Urine Concentration of S100B in Extremely Premature Infants	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a STIM2 binder may also engage these)

Protein	Name	Similarity
P83093	—	1.000	P83093 →
Q58CP9	—	1.000	Q58CP9 →
P70302	—	0.999	P70302 →
STIM1	Stromal interaction molecule 1	0.998	landscape →
P84903	—	0.998	P84903 →
Q95RG8	—	0.993	Q95RG8 →
Q17QK1	—	0.993	Q17QK1 →
A1Z7A6	—	0.991	A1Z7A6 →
Q1LYM3	—	0.991	Q1LYM3 →
G5EF60	—	0.991	G5EF60 →
O35711	—	0.991	O35711 →
A9C3W3	—	0.991	A9C3W3 →
A7YDW0	—	0.991	A7YDW0 →
P34609	—	0.990	P34609 →
O43150	—	0.990	O43150 →
Q7Z3E5	—	0.990	Q7Z3E5 →
Q3U1N2	—	0.990	Q3U1N2 →
Q8SWR2	—	0.990	Q8SWR2 →
B5E0H4	—	0.990	B5E0H4 →
G5EFD2	—	0.990	G5EFD2 →
P43125	—	0.990	P43125 →
Q8ND30	—	0.989	Q8ND30 →
P83038	—	0.989	P83038 →
Q5TH69	—	0.989	Q5TH69 →
P30630	—	0.989	P30630 →
Q3B7K9	—	0.989	Q3B7K9 →
Q6P730	—	0.989	Q6P730 →
Q9V407	—	0.989	Q9V407 →
B4HEJ6	—	0.989	B4HEJ6 →
P49802	—	0.989	P49802 →