SUCLG2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to SUCLG2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effects of Botulinum Toxin Injections in Patients With Hereditary Spastic Paraplegia	PHASE2/PHASE3	COMPLETED
Single Agent Regorafenib in First-line for Metastatic/Unresectable KIT/PDGFR Wild Type GIST	PHASE2	COMPLETED
Acetylcarnitine and Insulin Sensitivity	PHASE2	COMPLETED
Natural History Study of FDXR Mutation-related Mitochondriopathy	nan	COMPLETED
Development of a Predictive Model for the Risk of Metastatic Disease in PPGLs, a Retrospective Cohort Study	nan	NOT_YET_RECRUITING
Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors	nan	RECRUITING
Genes Associated With Development of Pulmonary Arterial Hypertension in Patients With Congenital Shunt Lesions	nan	RECRUITING
Limb Girdle Muscular Dystrophy Type 2E Recruitment Study	nan	UNKNOWN
Genetic Variants Associated With Adolescent Suicide Attempts	nan	COMPLETED
Influence of WNT4 VEZT FSHB and SIRT1 SNPs in Endometriosis: a Case Control Study of the Sardinian Population	nan	UNKNOWN
Investigations Into ISCU Myopathy or Iron Sulfur Scaffold U Protein Myopathy	nan	COMPLETED
Genetic Basis of Non Syndromic Congenital Diaphragmatic Hernia	nan	COMPLETED
The International Registry for Leigh Syndrome	nan	RECRUITING
Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide Riboside	nan	UNKNOWN
Hydroxychloroquin (HCQ) in chILD of Genetic Defect	nan	COMPLETED
Familial Partial Lipodystrophy Study	nan	COMPLETED
Protein Synthesis in the Brain of Patients With Fragile X Syndrome	nan	COMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus	nan	COMPLETED
GDF-15 as a Biomarker for Mitochondrial Disease	nan	COMPLETED
Muscle Tissue Bank for Muscular Dystrophy	nan	COMPLETED
Role of Amino Acids and Genetic Disorder in Pathogenesis of Heart Failure	nan	UNKNOWN
Pharmacogenomics of Antidepressant Response in Children and Adolescents	nan	COMPLETED
11C-Acetate PET/CT Non-FDG-Avid Tumors	nan	UNKNOWN
Precision Obesity Medicine: Genetic Prediction of Response to GLP-1/GIP Agonists.	nan	RECRUITING
Markers and Mechanisms of Macrovascular Disease in IDDM	nan	COMPLETED
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance	nan	COMPLETED
Using Next-generation Sequencing in the Diagnosis of Epilepsy and/or Intellectual Disability in a Pediatric Cohorte	nan	COMPLETED
Effects of Acute Energy Deficit and Aerobic Exercise on Muscle Quality	nan	COMPLETED
Gene Expression in Obesity and Insulin Resistance	nan	COMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a SUCLG2 binder may also engage these)

Protein	Name	Similarity
Q9Z2I8	—	1.000	Q9Z2I8 →
P53590	—	1.000	P53590 →
Q3MHX5	—	1.000	Q3MHX5 →
Q03184	—	1.000	Q03184 →
P53312	—	1.000	P53312 →
Q84LB6	—	1.000	Q84LB6 →
Q9Z2I9	—	1.000	Q9Z2I9 →
Q6K9N6	—	1.000	Q6K9N6 →
O97580	—	0.999	O97580 →
O94415	—	0.999	O94415 →
O82662	—	0.998	O82662 →
B3FHP0	—	0.997	B3FHP0 →
A5FHX8	—	0.997	A5FHX8 →
Q9YI36	—	0.997	Q9YI36 →
SUCLA2	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0.997	landscape →
Q9YI37	—	0.997	Q9YI37 →
P53589	—	0.996	P53589 →
Q4R517	—	0.995	Q4R517 →
Q9P567	—	0.995	Q9P567 →
A4WNM6	—	0.995	A4WNM6 →
Q148D5	—	0.995	Q148D5 →
A1BE51	—	0.995	A1BE51 →
A6GY30	—	0.995	A6GY30 →
A1AZH7	—	0.994	A1AZH7 →
Q1QQR3	—	0.994	Q1QQR3 →
B3E7B3	—	0.994	B3E7B3 →
A9BQA5	—	0.994	A9BQA5 →
P66867	—	0.993	P66867 →
Q57AX2	—	0.993	Q57AX2 →
B2S880	—	0.993	B2S880 →