SYPL1

Synaptophysin-like protein 1 · Q16563 · SYPL1 on Sugi Atlas →

0 patent compounds predicted against SYPL1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SYPL1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Minocycline for the Treatment of Early-Phase Schizophrenia PHASE3COMPLETED
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) PHASE2/PHASE3ACTIVE_NOT_RECRUITING
The Synapse Project PHASE2COMPLETED
Nilotinib in Huntington's Disease PHASE1UNKNOWN
A Clinical Study to Evaluate the Safety of MF1, a New Treatment for Parkinson's Disease-related Disorders (MF1 Study) PHASE1RECRUITING
Gene Therapy for Alzheimer's Disease Clinical Trial PHASE1COMPLETED
Application of 18F-CP6A PET Imaging in Synucleinopathies EARLY_PHASE1NOT_YET_RECRUITING
Phenylbutyrate for Monogenetic Developmental and Epileptic Encephalopathy EARLY_PHASE1ACTIVE_NOT_RECRUITING
Does BCG Vaccination Reduce Biomarkers of Alzheimer's Disease? EARLY_PHASE1ENROLLING_BY_INVITATION
Comparing Outcomes of Theta Burst Stimulation in Depression Using Advanced PET Imaging nanNOT_YET_RECRUITING
Toward Molecular Profiling of Parkinson's Disease in Easily Accessible Biological Matrices nanACTIVE_NOT_RECRUITING
In Vivo PET of Synaptic Density in Cognitive Disorders nanCOMPLETED
Combined Aerobic Exercise and Cognitive Training in Seniors at Increased Risk for Alzheimer's Disease nanNOT_YET_RECRUITING
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS nanRECRUITING
Urine Concentration of S100B in Extremely Premature Infants nanCOMPLETED
p11 Protein Levels in Patients With Major Depressive Disorder Treated With Citalopram nanCOMPLETED
STXBP1 and SYNGAP1 Related Disorders Natural History Study nanRECRUITING
Protein Synthesis in the Brain of Patients With Fragile X Syndrome nanCOMPLETED
Late Onset Alzheimer's Disease nanRECRUITING
miR-142-3p as Potential Biomarker of Synaptopathy in MS nanUNKNOWN
The Genetic Characterization of Dementia nanCOMPLETED
Analysis of Post-Translational Modifications of a Critical Protein Implicated in Amyotrophic Lateral Sclerosis nanCOMPLETED
The Swedish BioFINDER 2 Study nanRECRUITING
Association of Brain Derived Neurotrophic Factor (BDNF) rs6265 Gene Polymorphism With Susceptibility to Epilepsy nanUNKNOWN
Relationship of Gestational Age and Urine Concentration of S100B in Preterm and Term Infants in the First Week of Life nanCOMPLETED
Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases nanCOMPLETED
Exploring the Olfactory Mucosa, Blood and Urine for the Identification of Early Biomarkers of Parkinson's Disease, Atypical Parkinsonisms and Neurocognitive Disorders Due to Lewy Body Disease nanRECRUITING
Effects of Probiotics on Peripheral Immunity in Parkinson's Disease nanUNKNOWN
Early Recognition and Intervention in Siblings at High-risk for Neurodevelopmental Disorder nanUNKNOWN
Consequences of Mutations in the SPG7 Gene at the Heterozygous State nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SYPL1 binder may also engage these)

ProteinNameSimilarity
O09117 0.992 O09117 →
Q5VXT5 0.991 Q5VXT5 →
O62646 0.982 O62646 →
O89104 0.980 O89104 →
Q6GPN9 0.966 Q6GPN9 →
Q6ZUX7 0.963 Q6ZUX7 →
Q8BGA2 0.961 Q8BGA2 →
Q68DH5 0.960 Q68DH5 →
O15126 0.959 O15126 →
Q6AZD1 0.959 Q6AZD1 →
Q3SYY9 0.959 Q3SYY9 →
A2VE13 0.959 A2VE13 →
Q8BUV8 0.958 Q8BUV8 →
Q5F3F5 0.958 Q5F3F5 →
Q62737 0.958 Q62737 →
Q8C561 0.958 Q8C561 →
Q3ZC23 0.958 Q3ZC23 →
MAL2 Protein MAL2 0.958 landscape →
D3ZWZ9 0.958 D3ZWZ9 →
Q9JK95 0.958 Q9JK95 →
Q8CJ61 0.957 Q8CJ61 →
Q7ZZL8 0.957 Q7ZZL8 →
Q61462 0.957 Q61462 →
Q6P4P2 0.957 Q6P4P2 →
P56603 0.957 P56603 →
Q3MHV9 0.956 Q3MHV9 →
P22831 0.956 P22831 →
Q66IV3 0.956 Q66IV3 →
CYBA Cytochrome b-245 light chain 0.956 landscape →
O77735 0.956 O77735 →