TGOLN2

Trans-Golgi network integral membrane protein 2 · O43493 · TGOLN2 on Sugi Atlas →

0 patent compounds predicted against TGOLN2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to TGOLN2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Phase II Study of Simvastatin Plus Irinotecan, Fluorouracil, and Leucovorin(FOLFIRI) for Metastatic CRC PHASE2COMPLETED
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy PHASE2COMPLETED
Ambroxol as a Treatment for Parkinson's Disease Dementia PHASE2UNKNOWN
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
Phase II Trial of Lonafarnib (a Farnesyltransferase Inhibitor) for Progeria PHASE2COMPLETED
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Ambroxol as a Novel Disease Modifying Treatment for Lewy Body Dementia PHASE1/PHASE2NOT_YET_RECRUITING
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
The Study of Quadruple Therapy Quercetin, Zinc, Metformin, and EGCG as Adjuvant Therapy for Early, Metastatic Breast Cancer and Triple-negative Breast Cancer, a Novel Mechanism EARLY_PHASE1UNKNOWN
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
Quantification of GADD34 Expression in RA nanCOMPLETED
RAFTLIN-1 Levels in Axial Spondyloarthritis and Psoriatic Arthritis nanCOMPLETED
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Open-Label Study of Omega 3 Oil Supplementation for Aging-Related Cognitive Decline nanCOMPLETED
PET/CT Scans Using the Tracer 11C-Csar, a Bile Acid Analog, to Depict and Visualize Changes in the Hepatobiliary System in Patients With Primary Biliary Cholangitis Before and After Treatment. nanACTIVE_NOT_RECRUITING
Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study nanRECRUITING
Biomarker for Mucolipidosis Disorder Type I, II, III, IV (BioML) nanWITHDRAWN
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
Pediatric Evaluation and Registry for Liver Cholestasis in Canada nanRECRUITING
Fatty Acids Lipidome and Oxidative Stress in Liver Transplantation nanUNKNOWN
Transcriptomic Profile of Patients Treated With Different Modalities of Spinal Cord Stimulation nanUNKNOWN
Study of Constitutional Platelet Disease nanUNKNOWN
Renal Transporters After Renal Transplantation nanUNKNOWN
Incidence of Iron Deficiency in Polycythemia Vera (PV) and Association With Disease Features nanUNKNOWN
Understanding Alpha-Synuclein Spread in Parkinson's Disease Through Blood Biomarkers and Neuroimaging nanNOT_YET_RECRUITING
Statin Therapy and COVID-19 Infection nanCOMPLETED
Glycosylation in Patients With Galactosaemia nanCOMPLETED
PATH Trial: Personalized Approaches in the Treatment of Head and Neck Cancer nanNOT_YET_RECRUITING
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a TGOLN2 binder may also engage these)

ProteinNameSimilarity
Q62314 0.994 Q62314 →
Q62313 0.991 Q62313 →
P19814 0.990 P19814 →
Q4ZJY8 0.983 Q4ZJY8 →
Q9BXX2 0.983 Q9BXX2 →
A0A571BEE2 0.983 A0A571BEE2 →
Q28139 0.983 Q28139 →
Q91WD8 0.982 Q91WD8 →
Q6JHY2 0.982 Q6JHY2 →
Q13127 0.981 Q13127 →
Q8N2N9 0.981 Q8N2N9 →
P24587 0.981 P24587 →
Q5U7M7 0.981 Q5U7M7 →
Q9QZM6 0.981 Q9QZM6 →
Q03645 0.981 Q03645 →
Q6P902 0.981 Q6P902 →
F4HTH8 0.980 F4HTH8 →
P35662 0.980 P35662 →
Q70KF4 0.980 Q70KF4 →
Q5SRN2 0.980 Q5SRN2 →
Q9PJT6 0.980 Q9PJT6 →
Q9QX75 0.979 Q9QX75 →
A6QL64 0.979 A6QL64 →
Q96M34 0.979 Q96M34 →
Q8TCU4 0.979 Q8TCU4 →
A0A5F8MPU3 0.979 A0A5F8MPU3 →
P10322 0.979 P10322 →
Q28820 0.979 Q28820 →
A4FU49 0.979 A4FU49 →
O54963 0.978 O54963 →