TMEM33 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to TMEM33 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
The RECONSTRUCT Study - Reconstructing Disease Mechanisms in Asthma	PHASE4	COMPLETED
Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy	PHASE2	RECRUITING
Targeting Endoplasmic Reticulum Stress in Human Hypertension	PHASE1/PHASE2	RECRUITING
PBA Use for Treatment of ATF6-/- Patients	EARLY_PHASE1	SUSPENDED
Clinical Application of PET Imaging Targeting GPA33 in Malignant Tumors	nan	NOT_YET_RECRUITING
Effect of BMPR-2 Gene Mutations on Hemodynamic Response by Iloprost Inhalation in Pulmonary Arterial Hypertension	nan	COMPLETED
Gene Expression in Inflammatory Bowel Disease	nan	ENROLLING_BY_INVITATION
Investigation of Biomarkers in Susac Syndrome	nan	UNKNOWN
Oat Bran and Plasma Lipid and Fecal Bacteria in Coronary Artery Disease Patients	nan	COMPLETED
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy	nan	COMPLETED
Investigations of Juvenile Neuronal Ceroid Lipofuscinosis	nan	RECRUITING
New Markers of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Function in Sweat	nan	UNKNOWN
TAS1R1, TAS1R3, TLR2, TLR4, CA6 Gene Polymorphism on Dental Caries	nan	COMPLETED
Microbiome Acquisition and Progression of Inflammation and Airway Disease in Infants and Children With Cystic Fibrosis	nan	COMPLETED
Chromosome 5Q Gene Variants and Asthma-Related Traits	nan	COMPLETED
Natural History Study of ATP1A3-related Disease	nan	UNKNOWN
Molecular Phenotypes for Cystic Fibrosis Lung Disease	nan	COMPLETED
Prevalence and Risk Factors of Nephrocalcinosis in Children at Sohag University Hospital	nan	UNKNOWN
Gene Modifiers of Cystic Fibrosis Lung Disease	nan	ACTIVE_NOT_RECRUITING
sCD163 in ALS Patients	nan	COMPLETED
A Prospective Study of Advanced Diagnostics in People With an Unclear Diagnosis of Cystic Fibrosis	nan	NOT_YET_RECRUITING
Nasal Epithelial Cells/Blood Lymphocyte Markers for Cystic Fibrosis (CF)/CF Pulmonary Exacerbations	nan	COMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease	nan	RECRUITING
Stress and Treatment Response in Puerto Rican Children With Asthma	nan	COMPLETED
Clinical and Genetic Profile of Pediatric Patients With Cystic Fibrosis in Sohag.	nan	COMPLETED
The Role of DNA and RNA in NGS Analyses for Advaced Stage NSCLC Patients	nan	RECRUITING
DNA Analysis of Tumor Tissue From Patients With Acute Myeloid Leukemia	nan	COMPLETED
Impaired Secretory IgA and Mucosal Immunity in Cystic Fibrosis	nan	UNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH)	nan	COMPLETED
Role of TMEM219 Marker in Type 1 Diabetes	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a TMEM33 binder may also engage these)

Protein	Name	Similarity
Q9CR67	—	1.000	Q9CR67 →
Q9Z142	—	1.000	Q9Z142 →
Q5RF53	—	0.954	Q5RF53 →
Q6UWH6	—	0.954	Q6UWH6 →
Q62302	—	0.953	Q62302 →
Q5XIK2	—	0.951	Q5XIK2 →
Q4R5B4	—	0.951	Q4R5B4 →
Q5BJW3	—	0.951	Q5BJW3 →
Q5RFE0	—	0.950	Q5RFE0 →
Q2TBU2	—	0.950	Q2TBU2 →
Q9Y320	—	0.949	Q9Y320 →
Q8N2H4	—	0.949	Q8N2H4 →
A4K2N5	—	0.949	A4K2N5 →
Q58DA4	—	0.948	Q58DA4 →
A9JRA0	—	0.948	A9JRA0 →
Q10SM7	—	0.947	Q10SM7 →
A4K2W1	—	0.947	A4K2W1 →
Q78S06	—	0.946	Q78S06 →
Q86UB9	—	0.946	Q86UB9 →
Q5U4F4	—	0.946	Q5U4F4 →
Q5RDV3	—	0.945	Q5RDV3 →
Q9D710	—	0.945	Q9D710 →
VMA21	Vacuolar ATPase assembly integral membrane protein VMA21	0.945	landscape →
Q9GKZ4	—	0.944	Q9GKZ4 →
Q01685	—	0.944	Q01685 →
Q9CYV5	—	0.944	Q9CYV5 →
Q5ZJ06	—	0.943	Q5ZJ06 →
Q6DED0	—	0.942	Q6DED0 →
Q13454	—	0.941	Q13454 →
Q6GQ39	—	0.941	Q6GQ39 →