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Sugi Predict / Targets / TRMT1

TRMT1

tRNA (guanine(26)-N(2))-dimethyltransferase · Q9NXH9 · TRMT1 on Sugi Atlas →

0 patent compounds predicted against TRMT1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to TRMT1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis PHASE3COMPLETED
Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath Tumor PHASE1/PHASE2NOT_YET_RECRUITING
Effect of PAE Hydrogel Loaded With tRF-ASO-Exo on Patients With Diabetic Ocular Surface Diseases PHASE2NOT_YET_RECRUITING
Phase II Study of Simvastatin Plus Irinotecan, Fluorouracil, and Leucovorin(FOLFIRI) for Metastatic CRC PHASE2COMPLETED
Low-Dose Danazol for the Treatment of Telomere Related Diseases PHASE2COMPLETED
Nucleoside Therapy in Patients With Telomere Biology Disorders PHASE1RECRUITING
Safety, Tolerability and Pharmacokinetics of Benfo-Oxythiamine (B-OT) in Healthy Volunteers PHASE1COMPLETED
Mitochondrial Dysfunctions Driving Insulin Resistance nanCOMPLETED
Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study nanNOT_YET_RECRUITING
Impact Of Choline in Patients With NAFLD nanUNKNOWN
Impact of Weight Loss on the Human Sperm Epitranscriptome nanACTIVE_NOT_RECRUITING
Collection of Samples of Bone Marrow Aspiration From Patients With Myelodysplastic Syndrome nanACTIVE_NOT_RECRUITING
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress nanWITHDRAWN
Mitigating Mitochondrial RNA Release During Aging to Control Inflammation and Senescence nanNOT_YET_RECRUITING
MNGIE Natural History Study nanRECRUITING
Long-read Genome Sequencing for the Molecular Diagnosis of Dystonia nanRECRUITING
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma nanCOMPLETED
MYT1L Syndrome: a Rare Paediatric Genetic Syndrome Responsible for a Neurodevelopmental Disorder nanRECRUITING
EXtremely Early-onset Type 1 Diabetes EXtremely Early-onset Type 1 Diabetes (A Musketeers' Memorandum Study) nanRECRUITING
The Impact of Mitochondrial Dysfunction on Human Bone Cell Metabolism and Remodelling nanACTIVE_NOT_RECRUITING
Circulating Non-coding RNAs and Cardiovascular Outcomes in Patients With Dyslipidemia and Atherosclerosis nanUNKNOWN
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
miR-155 Expression in Episodic and Chronic Migraine nanUNKNOWN
Expression of TET1 Gene in Acute Leukaemia nanUNKNOWN
SMN Circular RNAs as Potential Biomarkers for the Therapeutic Response to Nusinersen in Spinal Muscular Atrophy Patients nanUNKNOWN
The Molecular Pathogenesis Study of Cataract nanUNKNOWN
Investigate eNAMPT in Multiple Myeloma Biology and Establish Its Role in Disease Progression nanCOMPLETED
Effectiveness Of Rapid Diagnostic Tests in the New Context of Low Malaria Endemicity in Zanzibar nanCOMPLETED
A Study of the Interaction Between Tumor Susceptibility Gene Glycine N-methyltransferase (GNMT) and Lung Cancer nanUNKNOWN
Effects of Fecal Microbiota Transplantation on Weight in Obese Patients With Non-alcoholic Fatty Liver Disease nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a TRMT1 binder may also engage these)

ProteinNameSimilarity
Q3TX08 — 0.997 Q3TX08 →
Q9SRU7 — 0.978 Q9SRU7 →
Q9D2Q2 — 0.974 Q9D2Q2 →
Q6DCD7 — 0.974 Q6DCD7 →
Q1HFZ0 — 0.973 Q1HFZ0 →
Q8CG07 — 0.973 Q8CG07 →
Q9LFU5 — 0.972 Q9LFU5 →
Q63186 — 0.971 Q63186 →
Q5ZLV4 — 0.971 Q5ZLV4 →
Q8CE96 — 0.970 Q8CE96 →
Q80YD1 — 0.969 Q80YD1 →
P37913 — 0.969 P37913 →
EIF2B4 Translation initiation factor eIF2B subunit delta 0.969 landscape →
Q9JLV6 — 0.968 Q9JLV6 →
A2AV36 — 0.968 A2AV36 →
P51432 — 0.968 P51432 →
Q8IYB8 — 0.967 Q8IYB8 →
Q5EBA1 — 0.967 Q5EBA1 →
Q2TBP8 — 0.967 Q2TBP8 →
Q4KLT3 — 0.967 Q4KLT3 →
Q96S55 — 0.967 Q96S55 →
Q5NVK5 — 0.967 Q5NVK5 →
P47823 — 0.967 P47823 →
Q91YR5 — 0.967 Q91YR5 →
P51400 — 0.966 P51400 →
NSUN2 RNA cytosine C(5)-methyltransferase NSUN2 0.966 landscape →
P41111 — 0.966 P41111 →
P78563 — 0.966 P78563 →
Q922X9 — 0.966 Q922X9 →
A5PK19 — 0.966 A5PK19 →