TRMT1L

tRNA (guanine(27)-N(2))-dimethyltransferase · Q7Z2T5 · TRMT1L on Sugi Atlas →

0 patent compounds predicted against TRMT1L, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to TRMT1L by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve) PHASE3WITHDRAWN
Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath Tumor PHASE1/PHASE2NOT_YET_RECRUITING
Danazol for Genetic Bone Marrow and Lung Disorders PHASE1/PHASE2COMPLETED
Phase II Study of Simvastatin Plus Irinotecan, Fluorouracil, and Leucovorin(FOLFIRI) for Metastatic CRC PHASE2COMPLETED
OMT-28 in Patients With Primary Mitochondrial Disease (PMD) (PMD-OPTION) PHASE2COMPLETED
Low-Dose Danazol for the Treatment of Telomere Related Diseases PHASE2COMPLETED
Nucleoside Therapy in Patients With Telomere Biology Disorders PHASE1RECRUITING
Safety, Tolerability and Pharmacokinetics of Benfo-Oxythiamine (B-OT) in Healthy Volunteers PHASE1COMPLETED
Mitochondrial Dysfunctions Driving Insulin Resistance nanCOMPLETED
Impact of Weight Loss on the Human Sperm Epitranscriptome nanACTIVE_NOT_RECRUITING
Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study nanNOT_YET_RECRUITING
MYT1L Syndrome: a Rare Paediatric Genetic Syndrome Responsible for a Neurodevelopmental Disorder nanRECRUITING
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress nanWITHDRAWN
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Collection of Samples of Bone Marrow Aspiration From Patients With Myelodysplastic Syndrome nanACTIVE_NOT_RECRUITING
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma nanCOMPLETED
Genotype-Phenotype Correlations of Late Infantile Neuronal Ceroid Lipofuscinosis nanCOMPLETED
Impact Of Choline in Patients With NAFLD nanUNKNOWN
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan nanENROLLING_BY_INVITATION
MNGIE Natural History Study nanRECRUITING
Telomerase Activity as a Marker For Mobilization Quality nanUNKNOWN
Long-read Genome Sequencing for the Molecular Diagnosis of Dystonia nanRECRUITING
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
SMN Circular RNAs as Potential Biomarkers for the Therapeutic Response to Nusinersen in Spinal Muscular Atrophy Patients nanUNKNOWN
miR-155 Expression in Episodic and Chronic Migraine nanUNKNOWN
Target of Suv420h1/2 in Hepatocytes nanRECRUITING
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
Mitigating Mitochondrial RNA Release During Aging to Control Inflammation and Senescence nanNOT_YET_RECRUITING
Circulating lncRNA and CV Morbidities in CKD and ESRD nanUNKNOWN
The Value of circRNAs (hsa_circ_0004001) in Early Diagnosis of HCC nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a TRMT1L binder may also engage these)

ProteinNameSimilarity
Q5R5T0 1.000 Q5R5T0 →
Q496Z9 1.000 Q496Z9 →
A2RSY6 1.000 A2RSY6 →
Q4R6C7 1.000 Q4R6C7 →
A5D7S3 1.000 A5D7S3 →
Q8BW70 0.985 Q8BW70 →
Q9DAU9 0.985 Q9DAU9 →
Q9XSW2 0.984 Q9XSW2 →
A9LLI8 0.984 A9LLI8 →
Q8C5W4 0.983 Q8C5W4 →
O17482 0.983 O17482 →
Q8R5F7 0.983 Q8R5F7 →
Q8C0M0 0.983 Q8C0M0 →
Q3US16 0.983 Q3US16 →
O93511 0.983 O93511 →
O88480 0.983 O88480 →
P79457 0.983 P79457 →
Q64398 0.983 Q64398 →
Q95171 0.983 Q95171 →
Q9ESK9 0.983 Q9ESK9 →
Q15326 0.982 Q15326 →
Q8CE96 0.982 Q8CE96 →
Q96M93 0.982 Q96M93 →
Q6NVF4 0.982 Q6NVF4 →
Q4R6Y8 0.982 Q4R6Y8 →
Q9QUG2 0.982 Q9QUG2 →
P03072 0.982 P03072 →
Q9EQM6 0.982 Q9EQM6 →
SMCHD1 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 0.982 landscape →
Q5R9R1 0.982 Q5R9R1 →