U2AF2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to U2AF2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Valproate and Levocarnitine in Children With Spinal Muscular Atrophy	PHASE3	UNKNOWN
Anastrozole or Fulvestrant in Treating Postmenopausal Patients With Breast Cancer	PHASE2	COMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia	nan	NOT_YET_RECRUITING
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population	nan	COMPLETED
Pumilio1 (PUM1) Expression, Sickle Cell Anemia, β-thalassemia Intermedia	nan	NOT_YET_RECRUITING
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis	nan	COMPLETED
Molecular Disease Profile of Hematological Malignancies	nan	UNKNOWN
Expression Pattern of HNRNPH1 and HNRNPK Genes in MPNs	nan	UNKNOWN
Efficacy and Safety Study of EGCG/Tocotrienol in 18 Patients With Splicing-mutation-mediated Cystic Fibrosis (CF)	nan	COMPLETED
NFC Changes in SLE Patients and Its Correlation With Anti-U1RNPAntibodies and Disease Activity	nan	UNKNOWN
SRSF2 Gene Mutation in Patients With t-MDS/AML	nan	COMPLETED
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact	nan	UNKNOWN
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Biocollection in MyeloDysplastic Syndrome (P-MDS)	nan	RECRUITING
Sodium Channel Splicing in Heart Failure Trial	nan	COMPLETED
Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing	nan	RECRUITING
Mechanisms of Cell Death in Spinal Muscular Atrophy	nan	COMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic	nan	COMPLETED
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes	nan	UNKNOWN
SMN Circular RNAs as Potential Biomarkers for the Therapeutic Response to Nusinersen in Spinal Muscular Atrophy Patients	nan	UNKNOWN
Becker Muscular Dystrophy - A Natural History Study to Predict Efficacy of Exon Skipping	nan	UNKNOWN
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma	nan	COMPLETED
Patient's Derived Organoids for Drug Screening in Glioblastoma	nan	NOT_YET_RECRUITING
Mutations and Phenotypes of Unclassifiable Inherited Bone Marrow Failure Syndromes	nan	RECRUITING
Genetic Factors Affecting the Severity of Beta Thalassemia	nan	COMPLETED
Research for Individualized Therapeutics in Rare Genetic Disease	nan	ENROLLING_BY_INVITATION
B3 for NMD: Bench to Bedside and Back	nan	ENROLLING_BY_INVITATION
Clinical Study of Spinal Muscular Atrophy	nan	COMPLETED
Outcome Measures and Biomarkers in a Cohort of Spinal Muscular Atrophy Type III/ IV Patients	nan	ACTIVE_NOT_RECRUITING
Transcriptomes Breast, Ovarian and Leukocyte Hereditary Genes Predisposing to Breast and / or Ovarian Cancer	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a U2AF2 binder may also engage these)

Protein	Name	Similarity
P26369	—	1.000	P26369 →
Q24562	—	0.998	Q24562 →
P90727	—	0.994	P90727 →
P90978	—	0.993	P90978 →
Q2QKB4	—	0.993	Q2QKB4 →
Q9ZR40	—	0.991	Q9ZR40 →
Q9ZR39	—	0.988	Q9ZR39 →
Q2R0Q1	—	0.988	Q2R0Q1 →
O23212	—	0.987	O23212 →
Q8L716	—	0.986	Q8L716 →
Q2QZL4	—	0.985	Q2QZL4 →
Q8WN55	—	0.985	Q8WN55 →
PTBP3	Polypyrimidine tract-binding protein 3	0.984	landscape →
Q91Z31	—	0.983	Q91Z31 →
Q29099	—	0.982	Q29099 →
Q5YD48	—	0.982	Q5YD48 →
Q5R9H4	—	0.981	Q5R9H4 →
Q923K9	—	0.981	Q923K9 →
Q8VH51	—	0.981	Q8VH51 →
Q9UKA9	—	0.981	Q9UKA9 →
Q66H20	—	0.980	Q66H20 →
Q91WT8	—	0.980	Q91WT8 →
Q9LQI9	—	0.979	Q9LQI9 →
Q9ASP6	—	0.979	Q9ASP6 →
Q00438	—	0.978	Q00438 →
PTBP1	Polypyrimidine tract-binding protein 1	0.978	landscape →
RBM39	RNA-binding protein 39	0.978	landscape →
Q9NQ94	—	0.977	Q9NQ94 →
Q5RC80	—	0.977	Q5RC80 →
Q9M427	—	0.977	Q9M427 →