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PTBP1

Polypyrimidine tract-binding protein 1 · P26599 · PTBP1 on Sugi Atlas →

15,791 patent compounds predicted against PTBP1, 11,045 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL684556 SCHEMBL684556 1.00 2/20
SCHEMBL1143226 SCHEMBL1143226 0.83 2/20
SCHEMBL685583 SCHEMBL685583 0.73 2/20
SCHEMBL686258 SCHEMBL686258 0.73 2/20
SCHEMBL685734 SCHEMBL685734 0.69 2/20
SCHEMBL686260 SCHEMBL686260 0.68 2/20
SCHEMBL686554 SCHEMBL686554 0.68 2/20
SCHEMBL683833 SCHEMBL683833 0.67 2/20
9,10-Phenanthrenequinone 9,10-Phenanthrenequinone (SCHEMBL43050) 0.59 2/20
SCHEMBL745377 SCHEMBL745377 0.57 2/20
SCHEMBL684996 SCHEMBL684996 0.56 2/20
SCHEMBL686319 SCHEMBL686319 0.56 2/20
SCHEMBL1225880 SCHEMBL1225880 0.53 2/20
SCHEMBL685652 SCHEMBL685652 0.53 2/20
SCHEMBL685002 SCHEMBL685002 0.51 2/20
SCHEMBL563010 SCHEMBL563010 0.50 2/20
SCHEMBL684981 SCHEMBL684981 0.49 2/20
SCHEMBL43327 SCHEMBL43327 0.48 2/20
SCHEMBL684012 SCHEMBL684012 0.47 2/20
SCHEMBL685025 SCHEMBL685025 0.46 2/20

Clinical trials — most relevant to PTBP1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Pumilio1 (PUM1) Expression, Sickle Cell Anemia, β-thalassemia Intermedia nanNOT_YET_RECRUITING
Predictive Value of Maternal Blood Protein Signatures in Preterm Birth nanCOMPLETED
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Stress Phenotypes and Preterm Birth nanRECRUITING
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Diagnosis of Inflammatory Bowel Disease nanNOT_YET_RECRUITING
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma nanCOMPLETED
SMN Circular RNAs as Potential Biomarkers for the Therapeutic Response to Nusinersen in Spinal Muscular Atrophy Patients nanUNKNOWN
Expression Pattern of HNRNPH1 and HNRNPK Genes in MPNs nanUNKNOWN
Study of Muscle Abnormalities in Patients With Specific Genetic Mutations nanCOMPLETED
Protein Expression as a Potential Diagnostic Biomarker of Cervical Dysplasia and/or Cancer nanCOMPLETED
Patient's Derived Organoids for Drug Screening in Glioblastoma nanNOT_YET_RECRUITING
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
Identification and Characterization of Novel Non-Coding Variants That Contribute to Genetic Disorders nanCOMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Melanocortin Gene Expression in Lymphocytes of Polymyalgia Patients nanCOMPLETED
CellulaR Injury and Preterm Birth nanCOMPLETED
Transcriptomes Breast, Ovarian and Leukocyte Hereditary Genes Predisposing to Breast and / or Ovarian Cancer nanCOMPLETED
Detection of Krupple Like Factor -1(KLF1/ EKLF) DNA Mutations in Beta Thalassemia Patients nanNOT_YET_RECRUITING
Efficacy and Safety Study of EGCG/Tocotrienol in 18 Patients With Splicing-mutation-mediated Cystic Fibrosis (CF) nanCOMPLETED
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes nanUNKNOWN
The Value of circRNAs (hsa_circ_0004001) in Early Diagnosis of HCC nanUNKNOWN
Molecular Disease Profile of Hematological Malignancies nanUNKNOWN
Protein Expression in Tumor Tissue Samples From Patients With Cancer of the Oropharynx nanCOMPLETED
Becker Muscular Dystrophy - A Natural History Study to Predict Efficacy of Exon Skipping nanUNKNOWN
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Screening of Specific Genes for Pigmented Villous Nodular Synovitis nanCOMPLETED
Identification of Novel Bio-markers for Environmental Enteropathy in Children Using an Evidence Based Approach nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PTBP1 binder may also engage these)

ProteinNameSimilarity
Q8WN55 — 1.000 Q8WN55 →
Q29099 — 1.000 Q29099 →
Q00438 — 0.998 Q00438 →
PTBP3 Polypyrimidine tract-binding protein 3 0.998 landscape →
Q91Z31 — 0.997 Q91Z31 →
P17225 — 0.995 P17225 →
Q9UKA9 — 0.995 Q9UKA9 →
Q9Z118 — 0.994 Q9Z118 →
Q66H20 — 0.994 Q66H20 →
Q8BHD7 — 0.991 Q8BHD7 →
Q09702 — 0.978 Q09702 →
O73932 — 0.977 O73932 →
U2AF2 Splicing factor U2AF 65 kDa subunit 0.977 landscape →
P26369 — 0.975 P26369 →
O57526 — 0.975 O57526 →
Q8GZ26 — 0.974 Q8GZ26 →
Q6ICX4 — 0.974 Q6ICX4 →
Q9M427 — 0.973 Q9M427 →
Q5R8F7 — 0.973 Q5R8F7 →
Q9LQI9 — 0.972 Q9LQI9 →
Q24562 — 0.972 Q24562 →
Q9SYG4 — 0.972 Q9SYG4 →
Q9EPH8 — 0.972 Q9EPH8 →
P16914 — 0.972 P16914 →
Q9NQ94 — 0.971 Q9NQ94 →
Q5ZLP8 — 0.969 Q5ZLP8 →
TIAL1 Nucleolysin TIAR 0.969 landscape →
Q39244 — 0.969 Q39244 →
Q6DEY7 — 0.969 Q6DEY7 →
P90727 — 0.968 P90727 →