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Sugi Predict / Targets / UBA7

UBA7

Ubiquitin-like modifier-activating enzyme 7 · P41226 · UBA7 on Sugi Atlas →

867 patent compounds predicted against UBA7, 803 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL1797199 SCHEMBL1797199 1.00 1/20
SCHEMBL1797979 SCHEMBL1797979 1.00 1/20
SCHEMBL11889885 SCHEMBL11889885 1.00 1/20
SCHEMBL1798231 SCHEMBL1798231 0.87 1/20
SCHEMBL1797397 SCHEMBL1797397 0.85 1/20
SCHEMBL1797565 SCHEMBL1797565 0.85 1/20
SCHEMBL12617804 SCHEMBL12617804 0.85 1/20
SCHEMBL17889849 SCHEMBL17889849 0.85 1/20
SCHEMBL1797617 SCHEMBL1797617 0.81 1/20
SCHEMBL1797027 SCHEMBL1797027 0.80 1/20
SCHEMBL1799418 SCHEMBL1799418 0.80 1/20
SCHEMBL1799420 SCHEMBL1799420 0.80 1/20
SCHEMBL1800297 SCHEMBL1800297 0.80 1/20
SCHEMBL12617501 SCHEMBL12617501 0.80 1/20
SCHEMBL1798208 SCHEMBL1798208 0.80 1/20
SCHEMBL11889779 SCHEMBL11889779 0.80 1/20
SCHEMBL12567176 SCHEMBL12567176 0.80 1/20
SCHEMBL1795527 SCHEMBL1795527 0.79 1/20
SCHEMBL12545942 SCHEMBL12545942 0.79 1/20
SCHEMBL17889861 SCHEMBL17889861 0.79 1/20

Clinical trials — most relevant to UBA7 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Can We Achieve 'high-quality' Weight Loss Through Supplementation and Exercise? the TRIM MUSCLE Study PHASE3COMPLETED
A Trial of Levodopa in Angelman Syndrome PHASE2/PHASE3COMPLETED
The Effect of Roxadustat on Renal Oxygenation in Diabetes Nephropathy PHASE2NOT_YET_RECRUITING
Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma PHASE2WITHDRAWN
Phase II Study of Vandetanib in Individuals With Kidney Cancer PHASE2COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
Clinical Trial of Levodopa/Carbidopa ( Sinemet) Therapy in Angel Man Syndrome nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure nanCOMPLETED
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors nanNOT_YET_RECRUITING
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma nanCOMPLETED
Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1 nanRECRUITING
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men nanRECRUITING
The Significance of Urine UbA52 In the Diagnosis of Diabetic Nephropathy nanCOMPLETED
Exercise Therapy to Reduce Heart Failure Symptoms; Sorting Mechanisms of Benefit nanCOMPLETED
Low Dose Melphalan and Bortezomib for AML and High-Risk MDS nanCOMPLETED
Study of Leukocyte Populations in Patients With Chronic Inflammatory nanUNKNOWN
Establishment of a Prospective Clinical-biological Database nanRECRUITING
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS nanRECRUITING
Natural History of Photoreceptor Degeneration in USH1B: Clinical Parameters and Validation of Functional Vision Tests in MYO7A nanRECRUITING
Relationship Between Nutritional State and Respiratory Muscle Weakness in Adult Patients With Bronchietasis nanUNKNOWN
Genetic Variation in TRAF3IP2 (rs13190932) nanRECRUITING
The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin nanUNKNOWN
Novel Urine-Based DNA Methylation Biomarkers for Urothelial Bladder Carcinoma Detection in Patients With Hematuria nanCOMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
The PREServation of MUScle Function in Critically Ill Patients (PRESMUS) nanUNKNOWN
Association of Autophagy-related Genes ,LncRNA and SNPs With Colorectal Cancer in Egyptian Population nanCOMPLETED
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a UBA7 binder may also engage these)

ProteinNameSimilarity
Q9DBK7 — 0.995 Q9DBK7 →
Q5JTZ9 — 0.995 Q5JTZ9 →
TARS2 Threonine--tRNA ligase, mitochondrial 0.991 landscape →
Q8VDP3 — 0.991 Q8VDP3 →
D3ZBP4 — 0.988 D3ZBP4 →
Q3UQ84 — 0.986 Q3UQ84 →
Q2V057 — 0.986 Q2V057 →
Q13724 — 0.985 Q13724 →
Q002B5 — 0.985 Q002B5 →
Q86U10 — 0.985 Q86U10 →
Q8VCZ9 — 0.984 Q8VCZ9 →
Q3ZBE0 — 0.983 Q3ZBE0 →
Q9CR25 — 0.982 Q9CR25 →
O43542 — 0.982 O43542 →
A1Y9I9 — 0.981 A1Y9I9 →
Q96SF2 — 0.981 Q96SF2 →
A4FUH1 — 0.981 A4FUH1 →
Q5RE82 — 0.981 Q5RE82 →
Q924H9 — 0.981 Q924H9 →
Q3TRM8 — 0.981 Q3TRM8 →
Q5RCH4 — 0.981 Q5RCH4 →
D3ZX08 — 0.981 D3ZX08 →
P51176 — 0.981 P51176 →
Q14CH7 — 0.980 Q14CH7 →
Q8TDZ2 — 0.980 Q8TDZ2 →
O55171 — 0.980 O55171 →
A6NM43 — 0.980 A6NM43 →
Q6ZSI9 — 0.980 Q6ZSI9 →
Q08DH8 — 0.980 Q08DH8 →
Q9JJL8 — 0.980 Q9JJL8 →