USE1

Vesicle transport protein USE1 · Q9NZ43 · USE1 on Sugi Atlas →

0 patent compounds predicted against USE1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to USE1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Pharmacogenetic Treatment With Anti-Glutaminergic Agents for Comorbid PTSD & AUD PHASE3COMPLETED
Comparison Between Botox and Magnesium Sulfate Effect in Treatment of Myofascial Pain Trigger Points Within the Masseter Muscle PHASE2/PHASE3NOT_YET_RECRUITING
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Reverse Transcriptase Inhibitors in AGS PHASE2COMPLETED
Effect of GET73 on MRS Measures of Central Glutamate and GABA in Individuals With Alcohol Use Disorder PHASE2COMPLETED
CHED - Congenital Hereditary Endothelial Dystrophy: New Paradigm Shift in Therapy Using Topical Eye Drops PHASE2UNKNOWN
Effect of Sarcosine on Symptomatology, Quality of Life, Oxidative Stress and Glutamatergic Parameters in Schizophrenia PHASE2COMPLETED
Stem Cell Models of Best Disease and Other Retinal Degenerative Diseases. nanCOMPLETED
Study of Chediak-Higashi Syndrome nanRECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Genetic Variation in CLTCL1 and Whole-body Glucose Control nanCOMPLETED
The Role of DNA and RNA in NGS Analyses for Advaced Stage NSCLC Patients nanRECRUITING
Study of the Genetic Factors Involved in Autism and Related Disorders nanRECRUITING
Insulin Detemir in Obesity Management nanACTIVE_NOT_RECRUITING
Exercise & Brain Health in MS nanCOMPLETED
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS nanRECRUITING
Susceptibility Genes in Autism Spectrum Disorders nanCOMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Cell Free Circulating Nucleic Acids as New Tumor Diagnostics From Human Plasma Samples. nanUNKNOWN
Protein Synthesis in the Brain of Patients With Fragile X Syndrome nanCOMPLETED
Targeting Potassium Channels to Reprogram Glioblastoma Microenvironment: in Vitro and in Vivo Studies nanUNKNOWN
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Association of Brain Derived Neurotrophic Factor (BDNF) rs6265 Gene Polymorphism With Susceptibility to Epilepsy nanUNKNOWN
Genetic Architecture of Chronic Inflammatory Demyelinating Polyradiculoneuropathy nanUNKNOWN
A Study on Risk Mutations of Vulnerability Genes of Schizophrenia nanUNKNOWN
Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN) nanRECRUITING
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy nanCOMPLETED
Development of a Risk Prediction Screening Tool for Opioid-Prescription Injury (STOP Injury) in Older Adults Initiated on Opioids From the Emergency Department nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a USE1 binder may also engage these)

ProteinNameSimilarity
Q9CQ56 1.000 Q9CQ56 →
Q7ZTY7 1.000 Q7ZTY7 →
Q4VBI7 0.981 Q4VBI7 →
Q5PPY2 0.980 Q5PPY2 →
A8E5U3 0.978 A8E5U3 →
Q5REB4 0.977 Q5REB4 →
Q8VDS8 0.976 Q8VDS8 →
Q66J30 0.975 Q66J30 →
Q5E9Y2 0.974 Q5E9Y2 →
P56962 0.973 P56962 →
STX18 Syntaxin-18 0.973 landscape →
Q5EA95 0.973 Q5EA95 →
Q8CG73 0.972 Q8CG73 →
Q9NWB7 0.972 Q9NWB7 →
Q3EBL9 0.972 Q3EBL9 →
Q68FW4 0.972 Q68FW4 →
Q2TBQ7 0.972 Q2TBQ7 →
Q7ZXA8 0.972 Q7ZXA8 →
Q96JB5 0.971 Q96JB5 →
Q6ID77 0.971 Q6ID77 →
Q5ZKJ4 0.971 Q5ZKJ4 →
CHCHD3 MICOS complex subunit MIC19 0.971 landscape →
Q5R561 0.971 Q5R561 →
Q5RAX7 0.971 Q5RAX7 →
A0A5G2QD80 0.970 A0A5G2QD80 →
Q6IVW0 0.970 Q6IVW0 →
Q3B8I4 0.970 Q3B8I4 →
Q4R5Q3 0.969 Q4R5Q3 →
Q3ZCF0 0.969 Q3ZCF0 →
P02683 0.969 P02683 →