Sugi Predict
/ Targets
/ STX18
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours |
|---|
Clinical trials — most relevant to STX18 by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| Evaluate the Efficacy and Safety of GZR18 Injection in Obese Subjects With Obstructive Sleep Apnea Receiving Positive Airway Pressure (PAP) Therapy |
PHASE3 | NOT_YET_RECRUITING |
| Prehospital Early Administration of Ketamine for Status Epilepticus in Epileptic Kids (PEAK-SEEK) |
PHASE2/PHASE3 | RECRUITING |
| Evaluate the Efficacy and Safety of GZR18 Injection in Obese Subjects With Obstructive Sleep Apnea Not Treated With Positive Airway Pressure (PAP) Therapy |
PHASE3 | NOT_YET_RECRUITING |
| A Study to Assess the Tolerability of a Single Dose of STX107 in Adults With Fragile X Syndrome |
PHASE2 | SUSPENDED |
| A Phase 2a Efficacy, Safety, Tolerability, and PK Study of SYT-510 in Participants With Generalized Anxiety Disorder |
PHASE2 | RECRUITING |
| Modulate Cellular Stress in the Immune Cells to Reduce Rate of Symptomatic Viral Infection |
PHASE2 | COMPLETED |
| Safety, Reactogenicity, and Immunogenicity Trial of STX-S SARS-CoV-2 Vaccine in Adults |
PHASE1 | COMPLETED |
| To Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of GB18 Injection in Healthy Participants |
PHASE1 | RECRUITING |
| A Study to Evaluate Satety, Tolerability, Biodistribution, Radiation Dosimetry, and Pharmacokinetics of SST001 in Healthy Volunteers, Patients With PD and Patients With MSA |
PHASE1 | NOT_YET_RECRUITING |
| Safety, Tolerability and Pharmacodynamics of SYNB1353 in Healthy Adult Volunteers |
PHASE1 | COMPLETED |
| A Phase 1 Study of STX-0712 in Patients With Advanced Hematological Malignancies (CMML and AML) |
PHASE1 | RECRUITING |
| Nilotinib in Huntington's Disease |
PHASE1 | UNKNOWN |
| A Phase 1 Single Dose and Multiple Ascending Dose Study to Assess the Relative Bioavailability, Food Effect, Safety, Tolerability and Pharmacokinetics of SYT-510 in Healthy Participants |
PHASE1 | COMPLETED |
| Phase 1 Trial of the TQB2928 Injection in Patients With Advanced Cancers |
PHASE1 | UNKNOWN |
| Phenylbutyrate for Monogenetic Developmental and Epileptic Encephalopathy |
EARLY_PHASE1 | ACTIVE_NOT_RECRUITING |
| MEG Study of Acute STX209 Effects in ASD |
EARLY_PHASE1 | COMPLETED |
| A Multicentric European Study to Promote Clinical Trial Readiness for STXBP1-related Disorders |
nan | RECRUITING |
| STXBP1 and SYNGAP1 Related Disorders Natural History Study |
nan | RECRUITING |
| Natural History Study in Pediatric Patients with STXBP1 Encephalopathy with Epilepsy |
nan | WITHDRAWN |
| Phenotyping and Identification of Biological Markers in STXBP1 Encephalopathy |
nan | NOT_YET_RECRUITING |
| Azithromycin in Post Diarrheal Haemolytic and Uremic Syndrome |
nan | COMPLETED |
| Natural History Study of SLC25A46 Mutation-related Mitochondriopathy |
nan | COMPLETED |
| Gene-STEPS: Shortening Time of Evaluation in Paediatric Epilepsy Services |
nan | UNKNOWN |
| Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA |
nan | RECRUITING |
| Comparing Outcomes of Theta Burst Stimulation in Depression Using Advanced PET Imaging |
nan | NOT_YET_RECRUITING |
| Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome |
nan | RECRUITING |
| Polycystic Ovary Syndrome in Type 1 Diabetes |
nan | NOT_YET_RECRUITING |
| Transcriptomic Profile of Patients Treated With Different Modalities of Spinal Cord Stimulation |
nan | UNKNOWN |
| Study of the Genetic Factors Involved in Autism and Related Disorders |
nan | RECRUITING |
| Role of Neurotransmission and Functional CNS Networks in Spasmodic Dysphonia |
nan | COMPLETED |
Related proteins — ESM-2 sequence neighbours (a STX18 binder may also engage these)