USO1

General vesicular transport factor p115 · O60763 · USO1 on Sugi Atlas →

0 patent compounds predicted against USO1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to USO1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Reverse Transcriptase Inhibitors in AGS PHASE2COMPLETED
A Study of CDX-1401 in Patients With Malignancies Known to Express NY-ESO-1 PHASE1/PHASE2COMPLETED
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Histocompatibility Leukocyte Antigen (HLA)-A*0201 Restricted Peptide Vaccine Therapy in Patients With Esophageal Cancer PHASE1/PHASE2COMPLETED
Histocompatibility Leukocyte Antigen (HLA)-A*0201 Restricted Peptide Vaccine Therapy in Patients With Gastric Cancer PHASE1/PHASE2COMPLETED
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS nanRECRUITING
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F nanACTIVE_NOT_RECRUITING
The Influence of Genetic Variations in ELAPOR1 or ELAPOR2 on Insulin Secretion and Glucose Regulation in Humans nanUNKNOWN
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Cytomegalovirus (CMV) MicroRNA Expression in Vivo and Immune Evasion Correlates nanCOMPLETED
Prospective Identification of Long QT Syndrome in Fetal Life nanCOMPLETED
Natural History of Photoreceptor Degeneration in USH1B: Clinical Parameters and Validation of Functional Vision Tests in MYO7A nanRECRUITING
Disease Biosignatures in ALS/FTD Spectrum: New Impactful Biological Perspectives Beyond Clinical Approaches nanRECRUITING
Rate of Progression in USH2A-related Retinal Degeneration nanACTIVE_NOT_RECRUITING
Hereditary Tubulointerstitial Nephritis nanCOMPLETED
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants nanRECRUITING
A Clinical Study on the Efficacy and Safety of Methotrexate (MTX) or Thiotepa (for MTX Intolerance) or Temozolomide (TMZ) Combined With Orelabrutinib and Selinexor in Relapsed/Refractory Primary or Secondary Central Nervous System Lymphoma(SELINA) nanRECRUITING
New Strategies of Genetic Study of Patients With Oculocutaneous Albinism nanCOMPLETED
Clinical and Molecular Description of PKD1 and PKD2 Mutation Negative Carriers in ADPKD nanCOMPLETED
Natural History Study in Subjects With Usher Syndrome nanCOMPLETED
Genetic Variation in CLTCL1 and Whole-body Glucose Control nanCOMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Iron Overload in African Americans nanCOMPLETED
A Study on Risk Mutations of Vulnerability Genes of Schizophrenia nanUNKNOWN
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease nanUNKNOWN
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Monogenic Diabetes Misdiagnosed as Type 1 nanRECRUITING
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a USO1 binder may also engage these)

ProteinNameSimilarity
P41541 1.000 P41541 →
P41542 1.000 P41542 →
Q9Z1Z0 1.000 Q9Z1Z0 →
Q9R1D7 0.976 Q9R1D7 →
Q5R581 0.973 Q5R581 →
Q9SV21 0.973 Q9SV21 →
Q9SV20 0.972 Q9SV20 →
Q07866 0.971 Q07866 →
D2SW95 0.970 D2SW95 →
Q8IWV8 0.970 Q8IWV8 →
Q5ZIA5 0.970 Q5ZIA5 →
Q96JJ3 0.969 Q96JJ3 →
Q7QG73 0.969 Q7QG73 →
A0JN39 0.969 A0JN39 →
Q92538 0.969 Q92538 →
O00291 0.969 O00291 →
O35841 0.968 O35841 →
COPB1 Coatomer subunit beta 0.968 landscape →
Q5R644 0.968 Q5R644 →
O60879 0.968 O60879 →
Q80UM3 0.968 Q80UM3 →
Q8BHL5 0.968 Q8BHL5 →
Q91XD6 0.967 Q91XD6 →
Q6P6Y1 0.967 Q6P6Y1 →
Q9JIF7 0.967 Q9JIF7 →
P37285 0.967 P37285 →
P83094 0.967 P83094 →
Q5ZMW3 0.967 Q5ZMW3 →
O62703 0.967 O62703 →
Q5R922 0.967 Q5R922 →