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Sugi Predict / Targets / YEATS2

YEATS2

YEATS domain-containing protein 2 · Q9ULM3 · YEATS2 on Sugi Atlas →

262 patent compounds predicted against YEATS2, 212 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL4446497 SCHEMBL4446497 1.00 1/20
SCHEMBL4444405 SCHEMBL4444405 0.84 1/20
SCHEMBL4433067 SCHEMBL4433067 0.83 1/20
SCHEMBL4436922 SCHEMBL4436922 0.75 1/20
SCHEMBL5006614 SCHEMBL5006614 0.69 1/20
SCHEMBL38659050 SCHEMBL38659050 0.68 1/20
SCHEMBL5000609 SCHEMBL5000609 0.68 1/20
SCHEMBL4438759 SCHEMBL4438759 0.67 1/20
SCHEMBL4435617 SCHEMBL4435617 0.66 1/20
SCHEMBL38658243 SCHEMBL38658243 0.66 1/20
SCHEMBL38659052 SCHEMBL38659052 0.66 1/20
SCHEMBL38659148 SCHEMBL38659148 0.66 1/20
SCHEMBL4440705 SCHEMBL4440705 0.65 1/20
SCHEMBL14845957 SCHEMBL14845957 0.65 1/20
SCHEMBL4437514 SCHEMBL4437514 0.64 1/20
SCHEMBL5000724 SCHEMBL5000724 0.64 1/20
SCHEMBL4445732 SCHEMBL4445732 0.63 1/20
SCHEMBL4440095 SCHEMBL4440095 0.63 1/20
SCHEMBL11437489 SCHEMBL11437489 0.63 1/20
SCHEMBL4435658 SCHEMBL4435658 0.63 1/20

Clinical trials — most relevant to YEATS2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Trial of the Histone-Deacetylase Inhibitor ITF2357 Followed by Mechlorethamine in Relapsed/Refractory Hodgkin's Lymphoma PHASE1/PHASE2COMPLETED
Genomic Predictors of Recurrent Pregnancy Loss nanRECRUITING
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Family Blood Pressure Program - HyperGEN nanCOMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Biomarkers in Samples of Bone Marrow From Patients With Acute Myeloid Leukemia nanCOMPLETED
Using Mobile Technology to Improve Self-Regulation nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Thermogenic Silencer Regulatory Factors in Humans nanACTIVE_NOT_RECRUITING
Elucidating the Molecular and Biochemical Basis of the Human AhR-mutation Disease nanUNKNOWN
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Family Blood Pressure Program - SAPPHIRe Network nanCOMPLETED
Family Blood Pressure Program - GENOA nanCOMPLETED
Family Blood Pressure Program - GenNet Network nanCOMPLETED
MYT1L Syndrome: a Rare Paediatric Genetic Syndrome Responsible for a Neurodevelopmental Disorder nanRECRUITING
Patient's Derived Organoids for Drug Screening in Glioblastoma nanNOT_YET_RECRUITING
Genomics and Epigenomics for New Insights in fEmale OAB (GENIE) Study nanCOMPLETED
Effect of Protein Intake on Post Prandial Hyperglycemia in Children and Adolescents With Type1 Diabetes Mellitus nanCOMPLETED
Stress and Treatment Response in Puerto Rican Children With Asthma nanCOMPLETED
Molecular Epidemiology of Essential Hypertension nanCOMPLETED
PCM1-JAK2 in Therapy Related Neoplasms nanUNKNOWN
Diet, Genetics, and CVD Risk Factor Response in Blacks nanCOMPLETED
Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models nanCOMPLETED
Gene Expression in Obesity and Insulin Resistance nanCOMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Genetic Variation in TRAF3IP2 (rs13190932) nanRECRUITING
A Study of the Interaction Between Tumor Susceptibility Gene Glycine N-methyltransferase (GNMT) and Lung Cancer nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a YEATS2 binder may also engage these)

ProteinNameSimilarity
Q3TUF7 — 0.999 Q3TUF7 →
Q7Z589 — 0.993 Q7Z589 →
Q8BMB0 — 0.993 Q8BMB0 →
Q15723 — 0.993 Q15723 →
Q9ULH7 — 0.992 Q9ULH7 →
Q0IHV2 — 0.992 Q0IHV2 →
Q2KHR2 — 0.991 Q2KHR2 →
Q58NQ4 — 0.991 Q58NQ4 →
A0JN51 — 0.990 A0JN51 →
Q96BD5 — 0.990 Q96BD5 →
NFRKB Nuclear factor related to kappa-B-binding protein 0.990 landscape →
Q6MZP7 — 0.990 Q6MZP7 →
P51611 — 0.990 P51611 →
Q6DDH6 — 0.990 Q6DDH6 →
Q641Z1 — 0.990 Q641Z1 →
P32519 — 0.990 P32519 →
Q9H334 — 0.990 Q9H334 →
Q60775 — 0.989 Q60775 →
P40645 — 0.989 P40645 →
Q9D2H6 — 0.989 Q9D2H6 →
A0A1L8H0H2 — 0.989 A0A1L8H0H2 →
Q571G4 — 0.989 Q571G4 →
Q99PM1 — 0.989 Q99PM1 →
Q9BTA9 — 0.989 Q9BTA9 →
Q9V4C8 — 0.989 Q9V4C8 →
Q5RCU4 — 0.989 Q5RCU4 →
Q7ZUV7 — 0.988 Q7ZUV7 →
P25425 — 0.988 P25425 →
Q96L91 — 0.988 Q96L91 →
Q0P5K4 — 0.988 Q0P5K4 →