ZDHHC9 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL20378481	1.00	2/20
SCHEMBL20378484	1.00	2/20
SCHEMBL20511973	1.00	2/20
SCHEMBL20511977	1.00	2/20
SCHEMBL26464591	0.90	2/20
SCHEMBL20511975	0.77	2/20
SCHEMBL20511978	0.77	2/20
SCHEMBL20378494	0.75	2/20
SCHEMBL20378498	0.75	2/20
SCHEMBL20378490	0.67	2/20
SCHEMBL20511976	0.67	2/20
SCHEMBL20378504	0.64	2/20
SCHEMBL20378506	0.64	2/20
SCHEMBL20378460	0.49	2/20
SCHEMBL20511974	0.49	2/20
SCHEMBL16846169	0.41	1/20

Clinical trials — most relevant to ZDHHC9 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Role of Pioglitazone in the Treatment of Non-alcoholic Steatohepatitis (NASH)	PHASE4	COMPLETED
Cholic Acid for Hepatic Steatosis in Lipodystrophy	PHASE2	COMPLETED
Choline Effects - Pre-symptomatic AD	PHASE1	COMPLETED
The Study of Quadruple Therapy Quercetin, Zinc, Metformin, and EGCG as Adjuvant Therapy for Early, Metastatic Breast Cancer and Triple-negative Breast Cancer, a Novel Mechanism	EARLY_PHASE1	UNKNOWN
Targeting zDHHC Enzymes to Counteract Alzheimer's Disease	nan	NOT_YET_RECRUITING
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes	nan	COMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity	nan	COMPLETED
Fatty Acid Metabolism and Insulin Sensitivity: the Role of Endurance Exercise	nan	COMPLETED
Serum Betatrophin Levels and Its Influencing Factors in Patients With Hyperthyroidism	nan	UNKNOWN
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
The LD Lync Study - Natural History Study of Lipodystrophy Syndromes	nan	RECRUITING
Systemic Biomarkers of Brain Injury From Hyperammonemia	nan	RECRUITING
for Adipose Tissue DIabetes VAriants (fATDIVA)	nan	COMPLETED
Genomic Dissection of a QTL Affecting the Lipid Profile	nan	WITHDRAWN
Gene Expression in Obesity and Insulin Resistance	nan	COMPLETED
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish)	nan	UNKNOWN
Genetic and Environmental Determinants of Triglycerides (GOLDN)	nan	COMPLETED
Target of Suv420h1/2 in Hepatocytes	nan	RECRUITING
Genes Involved in Lipid Disorders	nan	COMPLETED
Development of Biomarker for Development of Non-Alcoholic Steatohepatitis (NASH) in Children	nan	WITHDRAWN
Familial Partial Lipodystrophy Study	nan	COMPLETED
Lipoprotein Lipase Expression in Chronic Lymphocytic Leukemia	nan	COMPLETED
Genetic Origin of Lipid Disorders	nan	UNKNOWN
Lipidomic and Multi-Omics Profiling of Fatty Liver Disease in People With and Without HIV	nan	NOT_YET_RECRUITING
Study of Protein Translocation in Patients With Beta-Oxidation Disorders	nan	COMPLETED
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve	nan	UNKNOWN
Identification of Women With Severe Insulin Resistant Syndromes of Genetic Origin Among Patients With Classic Polycystic Ovary Syndrome (PCOS)	nan	NOT_YET_RECRUITING
Effects of Parenteral L-carnitine Supplementation in Premature Neonates	nan	COMPLETED
Epidemiology of Atherosclerosis	nan	COMPLETED
Impact Of Choline in Patients With NAFLD	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a ZDHHC9 binder may also engage these)

Protein	Name	Similarity
Q5R5J8	—	1.000	Q5R5J8 →
Q58DA8	—	1.000	Q58DA8 →
P59268	—	1.000	P59268 →
Q2TGJ1	—	0.993	Q2TGJ1 →
Q9NUE0	—	0.993	Q9NUE0 →
Q5Y5T2	—	0.992	Q5Y5T2 →
Q5RB84	—	0.992	Q5RB84 →
B3DN87	—	0.992	B3DN87 →
F1R013	—	0.991	F1R013 →
Q9FLM3	—	0.991	Q9FLM3 →
Q8IZN3	—	0.990	Q8IZN3 →
Q52T38	—	0.990	Q52T38 →
Q6FSS4	—	0.990	Q6FSS4 →
Q7ZVN4	—	0.989	Q7ZVN4 →
E9QCD3	—	0.989	E9QCD3 →
Q96MV8	—	0.989	Q96MV8 →
Q8VYP5	—	0.989	Q8VYP5 →
P0C7U3	—	0.988	P0C7U3 →
P59267	—	0.988	P59267 →
Q2TGJ4	—	0.988	Q2TGJ4 →
ZDHHC2	Palmitoyltransferase ZDHHC2	0.988	landscape →
Q14AK4	—	0.988	Q14AK4 →
ZDHHC20	Palmitoyltransferase ZDHHC20	0.988	landscape →
E7F587	—	0.987	E7F587 →
Q5M757	—	0.987	Q5M757 →
Q8BQQ1	—	0.987	Q8BQQ1 →
Q9SB58	—	0.987	Q9SB58 →
Q5BLG4	—	0.987	Q5BLG4 →
B1H1H3	—	0.987	B1H1H3 →
Q0VC89	—	0.987	Q0VC89 →