Sugi Predict

Sugi Predict / Targets / ZMPSTE24

ZMPSTE24

CAAX prenyl protease 1 homolog · O75844 · ZMPSTE24 on Sugi Atlas →

0 patent compounds predicted against ZMPSTE24, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to ZMPSTE24 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Assessment the Activity Value of Isotretinoin (13- Cis-Retinoic Acid ) in the Treatment of COVID-19 ( Isotretinoin in Treatment of COVID-19) (Randomized) PHASE3UNKNOWN
NEO100 and High-Grade Meningioma PHASE2RECRUITING
Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma PHASE1/PHASE2RECRUITING
Phase II Trial of Lonafarnib (a Farnesyltransferase Inhibitor) for Progeria PHASE2COMPLETED
Simvastatin + Cetuximab/Irinotecan in K-ras Mutant Colorectal Cancer (CRC) PHASE2COMPLETED
Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast Cancer PHASE2COMPLETED
Neurosteroids for PTSD in Veterans PHASE2COMPLETED
Combination Therapy With Isotretinoin and Tamoxifen Expected to Provide Complete Protection Against Severe Acute Respiratory Syndrome Coronavirus PHASE2UNKNOWN
Study of Sorafenib and Docetaxel in Metastatic Prostate Cancer PHASE2COMPLETED
Choline Effects - Pre-symptomatic AD PHASE1COMPLETED
Accelerated Aging, HIV Infection, Antiretroviral Therapies nanCOMPLETED
Use of Blood Biomarkers for the Early Diagnosis of Hepatocellular Carcinoma (HCC) nanUNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Genetic, Dietary and Environmental Influences on Vitamin D Metabolism nanCOMPLETED
Tecfidera Diffusion Tensor Imaging nanCOMPLETED
Study of a Candidate Gene Involved in Goldenhar Syndrome. nanCOMPLETED
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure nanRECRUITING
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD) nanCOMPLETED
Lipidomics Screening of Celecoxib in ex Vivo Human Whole Blood Assay - Part B nanCOMPLETED
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish) nanUNKNOWN
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma nanUNKNOWN
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
Identification of an Asthma Susceptibility Gene on 3P nanCOMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Genetics and Psychopathology in the 22q11 Deletion Syndrome nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease nanCOMPLETED
Investigate eNAMPT in Multiple Myeloma Biology and Establish Its Role in Disease Progression nanCOMPLETED
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a ZMPSTE24 binder may also engage these)

ProteinNameSimilarity
Q80W54 — 1.000 Q80W54 →
Q5R9K4 — 0.965 Q5R9K4 →
Q99KU0 — 0.962 Q99KU0 →
VMP1 Vacuole membrane protein 1 0.962 landscape →
Q91ZQ0 — 0.960 Q91ZQ0 →
Q6INE8 — 0.958 Q6INE8 →
Q0VCK9 — 0.957 Q0VCK9 →
Q6NYY9 — 0.956 Q6NYY9 →
Q68EQ9 — 0.955 Q68EQ9 →
CDS2 Phosphatidate cytidylyltransferase 2 0.953 landscape →
Q99L43 — 0.952 Q99L43 →
Q6AY30 — 0.952 Q6AY30 →
Q8BGS7 — 0.952 Q8BGS7 →
Q6AXM5 — 0.951 Q6AXM5 →
CEPT1 Choline/ethanolaminephosphotransferase 1 0.950 landscape →
Q9Z2A7 — 0.950 Q9Z2A7 →
Q9D020 — 0.950 Q9D020 →
Q9ERM3 — 0.950 Q9ERM3 →
A0JNC1 — 0.950 A0JNC1 →
Q5R839 — 0.949 Q5R839 →
Q9H0P0 — 0.949 Q9H0P0 →
Q8BXA5 — 0.949 Q8BXA5 →
O95427 — 0.949 O95427 →
O35052 — 0.948 O35052 →
Q5ZKJ0 — 0.948 Q5ZKJ0 →
Q61093 — 0.948 Q61093 →
B9N1F9 — 0.948 B9N1F9 →
P52649 — 0.948 P52649 →
Q28CY9 — 0.948 Q28CY9 →
Q9QZ71 — 0.947 Q9QZ71 →