CRY2 c.37G>C
Uncertain significance
Single submitter
Classification
Uncertain significance
ClinVar
Review
Single submitter ★☆☆☆
ClinVar · 1 submitter
gnomAD v4.1
Rare
Computational evidence
| Protein change | ||
| Missense predictors do not apply to this variant type. |
Variant & gene context
- Gene
- CRY2
- Coding
- c.37G>C
- MANE Select
- NM_021117
- Type
- single nucleotide variant
- Gene constraint
- LOEUF 0.596 · pLI 0.02 (gnomAD)
- Structure
- AlphaFold pLDDT 85.42
Similar variants
- CRY2 p.Ala12Glu Benign ★★ same type
- CRY2 p.Gly269= Benign ★★ same type
- CRY2 c.-5C>T Uncertain significance ★ same type
- CRY2 p.Ala12Val Uncertain significance ★ ⚠ same type
- CRY2 p.Ala14Glu Uncertain significance ★ ⚠ same type
- CRY2 p.Ala14Val Uncertain significance ★ ⚠ same type
- CRY2 p.Ala16Pro Uncertain significance ★ ⚠ same type
- CRY2 p.Ala260Val Uncertain significance ★ ⚠ same type
Built on 18 open, versioned datasets — ClinVar, gnomAD, AlphaMissense, REVEL, ClinGen & more — plus Sugi Variant's own cross-source analysis. Source data 2026-01–2026-10, ClinVar 2026-10. Full sources & versions →
Cite Sugi Variant
Gür T. Sugi Variant: A Deterministic Per-Variant Germline Reference from a Knowledge Graph for Humans and AI Agents. 2026. doi:10.5281/zenodo.21509445. This variant: https://sugi.bio/variant/cry2-c-37g-c (accessed [today's date]).
Preprint & method: sugi.bio/variant/method Machine-readable: this page as Markdown