ARL10 — 39 ClinVar variants
All ClinVar germline ARL10 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 36 flagged for review →
39 Uncertain significance
Full ARL10 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 36
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 31
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- ARL10 p.Ala16Thr Uncertain significance Single submitter
- ARL10 p.Ala49Pro Uncertain significance Single submitter
- ARL10 p.Arg136Ser Uncertain significance Single submitter
- ARL10 p.Arg165Gln Uncertain significance Single submitter
- ARL10 p.Arg200Trp Uncertain significance Single submitter
- ARL10 p.Arg42Pro Uncertain significance Single submitter
- ARL10 p.Arg53Cys Uncertain significance Single submitter
- ARL10 p.Asn185Ser Uncertain significance Single submitter
- ARL10 p.Asp177Glu Uncertain significance Single submitter
- ARL10 p.Asp208Asn Uncertain significance Single submitter
- ARL10 p.Glu123Gln Uncertain significance Single submitter
- ARL10 p.Glu145Lys Uncertain significance Single submitter
- ARL10 p.Glu44Asp Uncertain significance Single submitter
- ARL10 p.Glu69Asp Uncertain significance Single submitter
- ARL10 p.Gly43Glu Uncertain significance Single submitter
- ARL10 p.Gly87Asp Uncertain significance Single submitter
- ARL10 p.Gly89Cys Uncertain significance Single submitter
- ARL10 p.Ile129Thr Uncertain significance Single submitter
- ARL10 p.Ile220Val Uncertain significance Single submitter
- ARL10 p.Leu215Pro Uncertain significance Single submitter
- ARL10 p.Leu9Val Uncertain significance Single submitter
- ARL10 p.Met193Arg Uncertain significance Single submitter
- ARL10 p.Phe93Cys Uncertain significance Single submitter
- ARL10 p.Pro179Ser Uncertain significance Single submitter
- ARL10 p.Pro70Leu Uncertain significance Single submitter
- ARL10 p.Ser144Arg Uncertain significance Single submitter
- ARL10 p.Ser155Leu Uncertain significance Single submitter
- ARL10 p.Thr92Met Uncertain significance Single submitter
- ARL10 p.Val181Ile Uncertain significance Single submitter
- ARL10 p.Val80Met Uncertain significance Single submitter
- ARL10 p.Val82Met Uncertain significance Single submitter
Predictors split 5
The independent predictors disagree with each other — read with care.
All ARL10 variants
Uncertain significance 39
- p.Ala16Thr Single submitter ⚠
- p.Ala49Pro Single submitter ⚠
- p.Arg136Ser Single submitter ⚠
- p.Arg165Gln Single submitter ⚠
- p.Arg165Gly Single submitter
- p.Arg200Trp Single submitter ⚠
- p.Arg211Gln Single submitter
- p.Arg42Pro Single submitter ⚠
- p.Arg53Cys Single submitter ⚠
- p.Asn185Ser Single submitter ⚠
- p.Asp177Glu Single submitter ⚠
- p.Asp208Asn Single submitter ⚠
- p.Glu123Gln Single submitter ⚠
- p.Glu145Lys Single submitter ⚠
- p.Glu44Asp Single submitter ⚠
- p.Glu69Asp Single submitter ⚠
- p.Gly21Cys Single submitter ⚠
- p.Gly43Glu Single submitter ⚠
- p.Gly87Asp Single submitter ⚠
- p.Gly89Cys Single submitter ⚠
- p.Ile129Thr Single submitter ⚠
- p.Ile207Phe Single submitter ⚠
- p.Ile220Val Single submitter ⚠
- p.Leu215Pro Single submitter ⚠
- p.Leu9Val Single submitter ⚠
- p.Lys29Glu Single submitter ⚠
- p.Met193Arg Single submitter ⚠
- p.Phe93Cys Single submitter ⚠
- p.Pro102Thr Single submitter ⚠
- p.Pro179Ser Single submitter ⚠
- p.Pro70Leu Single submitter ⚠
- p.Ser144Arg Single submitter ⚠
- p.Ser155Leu Single submitter ⚠
- p.Thr92Met Single submitter ⚠
- p.Tyr138Cys Single submitter ⚠
- p.Val148Leu Single submitter
- p.Val181Ile Single submitter ⚠
- p.Val80Met Single submitter ⚠
- p.Val82Met Single submitter ⚠