B3GNT7 — 56 ClinVar variants
All ClinVar germline B3GNT7 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 52 flagged for review →
4 Likely benign · 52 Uncertain significance
Full B3GNT7 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 52
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 31
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- B3GNT7 p.Ala164Ser Uncertain significance Single submitter
- B3GNT7 p.Ala306Thr Uncertain significance Single submitter
- B3GNT7 p.Ala70Val Uncertain significance Single submitter
- B3GNT7 p.Arg154His Uncertain significance Single submitter
- B3GNT7 p.Arg273Gln Uncertain significance Single submitter
- B3GNT7 p.Arg356Ser Uncertain significance Single submitter
- B3GNT7 p.Arg359His Uncertain significance Single submitter
- B3GNT7 p.Arg396His Uncertain significance Single submitter
- B3GNT7 p.Asn59Thr Uncertain significance Single submitter
- B3GNT7 p.Asp202Asn Uncertain significance Single submitter
- B3GNT7 p.Asp210Asn Uncertain significance Single submitter
- B3GNT7 p.Cys317Ser Uncertain significance Single submitter
- B3GNT7 p.Gln107Pro Uncertain significance Single submitter
- B3GNT7 p.Gln33Glu Uncertain significance Single submitter
- B3GNT7 p.Glu160Lys Uncertain significance Single submitter
- B3GNT7 p.Glu37Lys Uncertain significance Single submitter
- B3GNT7 p.Gly286Glu Uncertain significance Single submitter
- B3GNT7 p.Gly301Ser Uncertain significance Single submitter
- B3GNT7 p.Ile220Met Uncertain significance Single submitter
- B3GNT7 p.Leu55Pro Uncertain significance Single submitter
- B3GNT7 p.Lys224Glu Uncertain significance Single submitter
- B3GNT7 p.Lys348Arg Uncertain significance Single submitter
- B3GNT7 p.Met332Ile Uncertain significance Single submitter
- B3GNT7 p.Phe350Leu Uncertain significance Single submitter
- B3GNT7 p.Pro379Ser Uncertain significance Single submitter
- B3GNT7 p.Pro38Thr Uncertain significance Single submitter
- B3GNT7 p.Pro58Arg Uncertain significance Single submitter
- B3GNT7 p.Pro71Ser Uncertain significance Single submitter
- B3GNT7 p.Thr216Ser Uncertain significance Single submitter
- B3GNT7 p.Val20Met Uncertain significance Single submitter
- B3GNT7 p.Val84Met Uncertain significance Single submitter
Predictors split 21
The independent predictors disagree with each other — read with care.
- B3GNT7 p.Arg109Trp Uncertain significance Single submitter
- B3GNT7 p.Arg10Gln Uncertain significance Single submitter
- B3GNT7 p.Arg118Cys Uncertain significance Single submitter
- B3GNT7 p.Arg159Cys Uncertain significance Single submitter
- B3GNT7 p.Arg161Trp Uncertain significance Single submitter
- B3GNT7 p.Arg186Cys Uncertain significance Single submitter
- B3GNT7 p.Asn246Ser Uncertain significance Single submitter
- B3GNT7 p.Glu105Val Uncertain significance Single submitter
- B3GNT7 p.Glu151Lys Uncertain significance Single submitter
- B3GNT7 p.Gly165Asp Uncertain significance Single submitter
- B3GNT7 p.His314Gln Uncertain significance Single submitter
- B3GNT7 p.Leu112Phe Uncertain significance Single submitter
- B3GNT7 p.Lys6Asn Uncertain significance Single submitter
- B3GNT7 p.Met122Lys Uncertain significance Single submitter
- B3GNT7 p.Met370Val Uncertain significance Single submitter
- B3GNT7 p.Phe101Leu Uncertain significance Single submitter
- B3GNT7 p.Pro127Ala Uncertain significance Single submitter
- B3GNT7 p.Thr211Asn Uncertain significance Single submitter
- B3GNT7 p.Thr23Met Uncertain significance Single submitter
- B3GNT7 p.Tyr283Phe Uncertain significance Single submitter
- B3GNT7 p.Val372Ala Uncertain significance Single submitter
All B3GNT7 variants
Likely benign 4
- p.Gly290Ser Single submitter
- p.Phe350= Single submitter
- p.Pro65Leu Single submitter
- p.Val8Ile Single submitter
Uncertain significance 52
- p.Ala164Ser Single submitter ⚠
- p.Ala306Thr Single submitter ⚠
- p.Ala70Val Single submitter ⚠
- p.Arg109Trp Single submitter ⚠
- p.Arg10Gln Single submitter ⚠
- p.Arg118Cys Single submitter ⚠
- p.Arg154His Single submitter ⚠
- p.Arg159Cys Single submitter ⚠
- p.Arg161Trp Single submitter ⚠
- p.Arg186Cys Single submitter ⚠
- p.Arg273Gln Single submitter ⚠
- p.Arg356Ser Single submitter ⚠
- p.Arg359His Single submitter ⚠
- p.Arg396His Single submitter ⚠
- p.Asn246Ser Single submitter ⚠
- p.Asn59Thr Single submitter ⚠
- p.Asp202Asn Single submitter ⚠
- p.Asp210Asn Single submitter ⚠
- p.Cys317Ser Single submitter ⚠
- p.Gln107Pro Single submitter ⚠
- p.Gln33Glu Single submitter ⚠
- p.Glu105Val Single submitter ⚠
- p.Glu151Lys Single submitter ⚠
- p.Glu160Lys Single submitter ⚠
- p.Glu37Lys Single submitter ⚠
- p.Gly165Asp Single submitter ⚠
- p.Gly286Glu Single submitter ⚠
- p.Gly301Ser Single submitter ⚠
- p.His314Gln Single submitter ⚠
- p.Ile220Met Single submitter ⚠
- p.Leu112Phe Single submitter ⚠
- p.Leu55Pro Single submitter ⚠
- p.Lys224Glu Single submitter ⚠
- p.Lys348Arg Single submitter ⚠
- p.Lys6Asn Single submitter ⚠
- p.Met122Lys Single submitter ⚠
- p.Met332Ile Single submitter ⚠
- p.Met370Val Single submitter ⚠
- p.Phe101Leu Single submitter ⚠
- p.Phe350Leu Single submitter ⚠
- p.Pro127Ala Single submitter ⚠
- p.Pro379Ser Single submitter ⚠
- p.Pro38Thr Single submitter ⚠
- p.Pro58Arg Single submitter ⚠
- p.Pro71Ser Single submitter ⚠
- p.Thr211Asn Single submitter ⚠
- p.Thr216Ser Single submitter ⚠
- p.Thr23Met Single submitter ⚠
- p.Tyr283Phe Single submitter ⚠
- p.Val20Met Single submitter ⚠
- p.Val372Ala Single submitter ⚠
- p.Val84Met Single submitter ⚠