BARD1 — 4109 ClinVar variants

All ClinVar germline BARD1 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 2148 flagged for review →

330 Pathogenic · 89 Pathogenic/Likely pathogenic · 114 Likely pathogenic · 403 Conflicting · 128 Benign · 361 Benign/Likely benign · 647 Likely benign · 2037 Uncertain significance

Full BARD1 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 2148

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors agree, ClinVar conflicts 229

ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification. · showing the 150 best-reviewed of 229

BARD1 p.Ala168Glu Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Ala168Gly Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ala168Val Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ala173Thr Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ala173Val Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ala189Thr Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ala189Val Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ala198Ser Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ala222Ser Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ala222Thr Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ala222Val Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ala25Pro Conflicting Single submitter
BARD1-related cancer predisposition
BARD1 p.Ala33Pro Conflicting Single submitter
BARD1-related cancer predisposition
BARD1 p.Ala33Val Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ala413Thr Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ala502Val Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ala613Glu Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Arg194Lys Conflicting Single submitter
BARD1-related cancer predisposition
BARD1 p.Arg21Pro Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Arg370Leu Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Arg406Gln Conflicting Single submitter
BARD1-related cancer predisposition
BARD1 p.Arg406Gly Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Arg58Lys Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Arg641Gln Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Arg642Gly Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Arg642Thr Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Arg749Lys Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asn118His Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asn118Ser Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asn134His Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asn134Thr Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asn18Lys Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asn215Ser Conflicting Single submitter
BARD1-related cancer predisposition
BARD1 p.Asn219Ser Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asn255Ser Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asn295Ser Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asn318Asp Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asn319Ser Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asn326Asp Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asn326Ser Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asn356Ile Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asn356Lys Conflicting Single submitter
BARD1-related cancer predisposition
BARD1 p.Asn419Asp Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asn419Ser Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asn55Asp Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asn626Ser Conflicting Single submitter
Breast and/or ovarian cancer
BARD1 p.Asn718Ser Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Asn73Asp Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Asp102Asn Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asp122Asn Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asp126Ala Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asp172Asn Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asp190Asn Conflicting Single submitter
Breast and/or ovarian cancer
BARD1 p.Asp190His Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Asp230Glu Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asp29Ala Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Asp29Val Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Asp346Asn Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Asp385Asn Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asp710Val Conflicting Single submitter
BARD1-related cancer predisposition
BARD1 p.Asp727Asn Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asp727Glu Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Asp765Asn Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Cys336Tyr Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Cys362Gly Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Cys368Trp Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Cys53Trp Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Cys53Tyr Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Cys71Ser Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Cys743Arg Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Cys83Arg Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Gln206Arg Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Gln206Lys Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Gln216Arg Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Gln237Glu Conflicting Single submitter
BARD1-related cancer predisposition
BARD1 p.Gln449Arg Conflicting Single submitter
hereditary breast ovarian cancer syndrome
BARD1 p.Gln93Arg Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Glu119Lys Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Glu193Lys Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Glu213Lys Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Glu270Gln Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Glu287Val Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Glu317Gln Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Glu317Gly Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Glu361Asp Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Glu587Asp Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Glu587Lys Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Glu748Asp Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Glu748Lys Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Glu771Gln Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Gly203Arg Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Gly227Asp Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Gly373Asp Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Gly374Asp Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Gly82Ala Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.His116Tyr Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.His324Arg Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.His325Arg Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.His325Gln Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.His685Arg Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.His686Arg Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.His746Arg Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ile169Val Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ile249Val Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Ile254Leu Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ile258Thr Conflicting Single submitter
BARD1-related cancer predisposition
BARD1 p.Ile286Met Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ile332Val Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ile340Val Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ile357Thr Conflicting Single submitter
BARD1-related cancer predisposition
BARD1 p.Ile357Val Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Ile388Leu Conflicting Single submitter
hereditary breast ovarian cancer syndrome
BARD1 p.Ile388Val Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ile441Val Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ile692Leu Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ile692Thr Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ile692Val Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ile702Val Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Ile764Thr Conflicting Single submitter
BARD1-related disorder
BARD1 p.Leu132Val Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Leu220Ser Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Leu239Gln Conflicting Single submitter
Breast and/or ovarian cancer
BARD1 p.Leu266Phe Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Leu316Val Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Leu390Ile Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Leu416Arg Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Leu572Phe Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Leu742Met Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Leu742Phe Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Leu742Val Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Leu775Phe Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Lys127Glu Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Lys130Arg Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Lys130Thr Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Lys140Asn Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Lys292Asn Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Lys311Asn Conflicting Single submitter
BARD1-related disorder
BARD1 p.Lys311Glu Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Lys379Arg Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Lys423Arg Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Lys503Arg Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Lys643Arg Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Lys684Arg Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Lys706Glu Conflicting Single submitter
BARD1-related cancer predisposition
BARD1 p.Met104Val Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Met383Arg Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Met383Ile Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Met383Leu Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Met383Lys Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Met383Val Conflicting Single submitter
hereditary neoplastic syndrome

Predicted LoF vs a conflicting call 23

ClinVar submitters conflict, and it's a predicted loss-of-function change in a gene where LoF causes disease — flagged for review, not resolved (verify NMD-escape for C-terminal truncations). Non-missense.

BARD1 c.1315-2A>G Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 c.1396-5_1396-2del Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 c.1568+2dup Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 c.1811-10_1811-2del Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 c.1811-1G>C Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 c.1904-1G>T Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 c.1904-2_1904-1del Conflicting Single submitter
hereditary breast carcinoma
BARD1 c.1904-2A>T Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 c.1904-2del Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 c.2001+2T>C Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 c.2002-1G>A Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 c.2002-1G>C Conflicting Single submitter
hereditary breast carcinoma
BARD1 c.2002-1G>T Conflicting Single submitter
hereditary breast ovarian cancer syndrome
BARD1 c.2002-2A>C Conflicting Single submitter
hereditary breast carcinoma
BARD1 c.2002-2A>G Conflicting Single submitter
hereditary breast ovarian cancer syndrome
BARD1 c.2002-2A>T Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 c.216-1G>A Conflicting Single submitter
hereditary breast carcinoma
BARD1 c.216-1G>C Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Gln6Ter Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Ile764fs Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Leu513Ter Conflicting Single submitter
hereditary breast carcinoma
BARD1 p.Leu668Ter Conflicting Single submitter
hereditary neoplastic syndrome
BARD1 p.Met1Ile Conflicting Single submitter
hereditary neoplastic syndrome

Predictors lean, ClinVar uncertain 1207

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 1207

BARD1 p.Ala136Ser Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ala136Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala173Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ala175Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala195Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala198Pro Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala198Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala200Val Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ala23Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala25Val Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ala262Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala283Pro Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ala283Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala283Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala33Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala33Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala35Asp Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala35Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala35Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala35Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala421Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala421Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala435Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala435Val Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ala460Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala460Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala468Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala518Asp Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala518Val Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ala522Ser Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ala522Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala554Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala589Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala613Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ala724Glu Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala724Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala758Pro Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala758Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala90Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg10Pro Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg112Pro Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg129Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg150Gln Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg150Pro Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg155Lys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg15Ser Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg194Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg201Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg201Ile Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg21Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg21Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg294Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg31Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg335Lys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg38Cys Uncertain significance Multiple submitters
hereditary breast ovarian cancer syndrome
BARD1 p.Arg38Pro Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg38Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg405Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg405Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg424Ser Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg427Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg427Ile Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg427Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg43Cys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg43Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg43His Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg43Leu Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg43Ser Uncertain significance Multiple submitters
BARD1-related disorder
BARD1 p.Arg52His Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg52Pro Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg565Leu Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg566Lys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg5Pro Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg642Lys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg659Lys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg661Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg661Ser Uncertain significance Multiple submitters
BARD1-related cancer predisposition
BARD1 p.Arg664Lys Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg705Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg705Lys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg725Ile Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg725Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg725Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg749Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg749Thr Uncertain significance Multiple submitters
BARD1-related disorder
BARD1 p.Arg751Pro Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg8Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg99Lys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn134Ser Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asn141Ser Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asn18Asp Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asn18Ser Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asn215Ile Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn215Tyr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn219Lys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn255Asp Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn255Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn326His Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn380Asp Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asn382Asp Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn425Lys Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asn455Asp Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asn494Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn524His Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn549Ser Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asn561Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn690Lys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn744Asp Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asn744Lys Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asn98Asp Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn98Lys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn98Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp102Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp117Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp122Val Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asp126Asn Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp135Asn Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asp135Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp172Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp178Asn Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp190Glu Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp190Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp190Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp230Asn Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asp230Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp259Asn Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asp290Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asp346Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp346Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp3Asn Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp3Tyr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp440Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp440Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp458Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp458His Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asp500Asn Uncertain significance Multiple submitters
BARD1-related cancer predisposition
BARD1 p.Asp500Glu Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp500His Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp500Tyr Uncertain significance Multiple submitters
BARD1-related cancer predisposition
BARD1 p.Asp500Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp532Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asp536Asn Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp601Asn Uncertain significance Multiple submitters
BARD1-related cancer predisposition
BARD1 p.Asp673Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asp673Tyr Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asp712Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp727Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp729Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp729His Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asp729Tyr Uncertain significance Multiple submitters
hereditary neoplastic syndrome

Predictors split 689

The independent predictors disagree with each other — read with care. · showing the 150 best-reviewed of 689

BARD1 p.Ala212Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ala212Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala39Thr Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ala39Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala40Thr Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ala435Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala468Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala468Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala485Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala485Val Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ala518Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala589Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala589Val Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ala594Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala594Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala638Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala721Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala721Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala721Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala724Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ala724Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala758Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ala758Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg112Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg13Lys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg13Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg150Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg150Leu Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg15Cys Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg15His Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg194Trp Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg21Cys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg31Cys Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg322Cys Uncertain significance Multiple submitters
BARD1-related cancer predisposition
BARD1 p.Arg322Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg337Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg38Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg38His Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg424Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg43Pro Uncertain significance Multiple submitters
hereditary breast ovarian cancer syndrome
BARD1 p.Arg49Cys Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg529Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg52Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg565Cys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg5Trp Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg641Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg658Cys Benign/Likely benign Multiple submitters
Hereditary cancer
BARD1 p.Arg658Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg658Pro Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Arg659Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg659Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg664Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg751Gln Uncertain significance Multiple submitters
Breast and/or ovarian cancer
BARD1 p.Arg751Trp Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg8Lys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg8Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Arg99Thr Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asn326Tyr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn356Tyr Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asn425Ser Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asn488Asp Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn488Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn524Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn55Tyr Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asn663Lys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asn663Ser Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asn98His Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp102Val Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asp126Tyr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp230Tyr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp259Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp29Asn Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp346Tyr Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asp385Tyr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp42His Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp42Tyr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp440Asn Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp495Asn Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp495Glu Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Asp508Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp508Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp532Asn Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp535Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp536His Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp689Asn Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp689Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp712Asn Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp727His Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp741Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp741His Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp741Tyr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Asp765Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Cys108Arg Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Cys108Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Cys620Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Cys628Ser Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Cys639Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Gln245His Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Gln482His Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Gln615Glu Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Gln666Glu Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Gln701Glu Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Gln701Leu Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Gln730Lys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Gln735Arg Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Glu225Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Glu445Lys Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Glu45Lys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Glu537Gln Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Glu537Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Glu580Gly Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Glu587Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Glu665Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Glu740Lys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Glu748Gln Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Glu748Gly Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Gly30Cys Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Gly451Glu Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Gly505Arg Uncertain significance Multiple submitters
hereditary breast ovarian cancer syndrome
BARD1 p.Gly505Glu Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Gly517Arg Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Gly527Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Gly574Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Gly574Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Gly576Ala Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Gly576Glu Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Gly656Val Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Gly698Arg Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Gly698Asp Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Gly698Ser Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Gly699Ala Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Gly753Ser Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.His426Asp Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.His471Arg Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.His471Tyr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.His483Leu Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.His723Tyr Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ile143Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ile214Ser Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ile332Met Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ile437Val Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ile441Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ile509Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ile56Ser Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ile702Asn Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ile702Phe Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ile717Asn Uncertain significance Multiple submitters
hereditary breast carcinoma
BARD1 p.Ile738Val Benign/Likely benign Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ile92Thr Uncertain significance Multiple submitters
hereditary neoplastic syndrome
BARD1 p.Ile97Lys Uncertain significance Multiple submitters
hereditary neoplastic syndrome

All BARD1 variants

Pathogenic 330

Showing the top 300 by review status; the full set is in the sitemap.

p.Ala173fs Multiple submitters hereditary breast carcinoma
p.Ala198fs Multiple submitters hereditary breast carcinoma
p.Ala200fs Multiple submitters hereditary breast carcinoma
p.Ala25fs Multiple submitters BARD1-related cancer predisposition
p.Ala589fs Multiple submitters hereditary breast carcinoma
p.Ala90_Trp91insTer Multiple submitters hereditary neoplastic syndrome
p.Arg150Ter Multiple submitters BARD1-related cancer predisposition
p.Arg155Ter Multiple submitters hereditary neoplastic syndrome
p.Arg327Ter Multiple submitters hereditary neoplastic syndrome
p.Arg335Ter Multiple submitters hereditary breast carcinoma
p.Arg378fs Multiple submitters BARD1-related cancer predisposition
p.Arg424fs Multiple submitters hereditary neoplastic syndrome
p.Arg99fs Multiple submitters hereditary neoplastic syndrome
p.Asn219fs Multiple submitters hereditary neoplastic syndrome
p.Asn549fs Multiple submitters hereditary breast carcinoma
p.Asn626fs Multiple submitters hereditary neoplastic syndrome
p.Asn98fs Multiple submitters hereditary neoplastic syndrome
p.Asp172fs Multiple submitters hereditary neoplastic syndrome
p.Asp458fs Multiple submitters hereditary breast carcinoma
p.Asp500fs Multiple submitters hereditary breast carcinoma
p.Cys362Ter Multiple submitters hereditary neoplastic syndrome
p.Cys83Ter Multiple submitters hereditary breast carcinoma
p.Cys86Ter Multiple submitters hereditary breast carcinoma
p.Gln106Ter Multiple submitters hereditary breast carcinoma
p.Gln166Ter Multiple submitters BARD1-related cancer predisposition
p.Gln176Ter Multiple submitters hereditary neoplastic syndrome
p.Gln177Ter Multiple submitters hereditary breast carcinoma
p.Gln216fs Multiple submitters BARD1-related disorder
p.Gln237Ter Multiple submitters hereditary neoplastic syndrome
p.Gln245Ter Multiple submitters hereditary neoplastic syndrome
p.Gln285_Ile286insTer Multiple submitters hereditary breast carcinoma
p.Gln350Ter Multiple submitters hereditary breast carcinoma
p.Gln482Ter Multiple submitters hereditary breast carcinoma
p.Gln564Ter Multiple submitters BARD1-related cancer predisposition
p.Gln582Ter Multiple submitters hereditary neoplastic syndrome
p.Gln615Ter Multiple submitters hereditary breast carcinoma
p.Gln93Ter Multiple submitters hereditary neoplastic syndrome
p.Glu225Ter Multiple submitters hereditary breast carcinoma
p.Glu234Ter Multiple submitters hereditary neoplastic syndrome
p.Glu270fs Multiple submitters hereditary breast carcinoma
p.Glu270Ter Multiple submitters hereditary neoplastic syndrome
p.Glu547Ter Multiple submitters hereditary neoplastic syndrome
p.Glu587fs Multiple submitters hereditary breast carcinoma
p.Glu634Ter Multiple submitters hereditary neoplastic syndrome
p.Gly203Ter Multiple submitters hereditary breast carcinoma
p.Gly428fs Multiple submitters hereditary breast carcinoma
p.Gly428Ter Multiple submitters hereditary neoplastic syndrome
p.Gly451fs Multiple submitters hereditary breast carcinoma
p.Gly505fs Multiple submitters hereditary neoplastic syndrome
p.Gly527fs Multiple submitters hereditary neoplastic syndrome
p.Gly82Ter Multiple submitters hereditary breast carcinoma
p.His325fs Multiple submitters hereditary neoplastic syndrome
p.His459fs Multiple submitters hereditary neoplastic syndrome
p.His506fs Multiple submitters hereditary neoplastic syndrome
p.His606fs Multiple submitters hereditary neoplastic syndrome
p.Ile332_Ser333insTer Multiple submitters hereditary neoplastic syndrome
p.Ile56_Leu57insTer Multiple submitters hereditary neoplastic syndrome
p.Ile591fs Multiple submitters hereditary neoplastic syndrome
p.Leu101fs Multiple submitters hereditary neoplastic syndrome
p.Leu275fs Multiple submitters hereditary breast carcinoma
p.Leu316Ter Multiple submitters hereditary neoplastic syndrome
p.Leu341fs Multiple submitters hereditary neoplastic syndrome
p.Leu417fs Multiple submitters hereditary neoplastic syndrome
p.Leu431fs Multiple submitters hereditary neoplastic syndrome
p.Leu465Ter Multiple submitters hereditary neoplastic syndrome
p.Leu572fs Multiple submitters hereditary breast carcinoma
p.Lys171fs Multiple submitters hereditary breast carcinoma
p.Lys205fs Multiple submitters hereditary neoplastic syndrome
p.Lys209fs Multiple submitters hereditary neoplastic syndrome
p.Lys321Ter Multiple submitters hereditary neoplastic syndrome
p.Lys371Ter Multiple submitters hereditary neoplastic syndrome
p.Lys475_Val476insTer Multiple submitters hereditary neoplastic syndrome
p.Lys540fs Multiple submitters hereditary neoplastic syndrome
p.Lys595_Lys596insTer Multiple submitters hereditary breast carcinoma
p.Lys596fs Multiple submitters hereditary breast carcinoma
p.Lys650fs Multiple submitters hereditary neoplastic syndrome
p.Pro252fs Multiple submitters hereditary neoplastic syndrome
p.Pro300fs Multiple submitters hereditary neoplastic syndrome
p.Pro396fs Multiple submitters hereditary neoplastic syndrome
p.Pro442fs Multiple submitters hereditary breast carcinoma
p.Pro610fs Multiple submitters hereditary breast carcinoma
p.Pro89fs Multiple submitters hereditary breast carcinoma
p.Ser148Ter Multiple submitters hereditary neoplastic syndrome
p.Ser162fs Multiple submitters hereditary neoplastic syndrome
p.Ser179_Tyr180insTer Multiple submitters BARD1-related cancer predisposition
p.Ser179Ter Multiple submitters hereditary breast carcinoma
p.Ser22fs Multiple submitters hereditary breast carcinoma
p.Ser293fs Multiple submitters
p.Ser339fs Multiple submitters hereditary neoplastic syndrome
p.Ser342fs Multiple submitters hereditary neoplastic syndrome
p.Ser436fs Multiple submitters hereditary breast carcinoma
p.Ser443fs Multiple submitters hereditary breast carcinoma
p.Ser496Ter Multiple submitters hereditary neoplastic syndrome
p.Ser541Ter Multiple submitters hereditary neoplastic syndrome
p.Ser551Ter Multiple submitters hereditary neoplastic syndrome
p.Ser553fs Multiple submitters hereditary neoplastic syndrome
p.Ser555fs Multiple submitters hereditary breast carcinoma
p.Ser575fs Multiple submitters hereditary neoplastic syndrome
p.Ser76fs Multiple submitters hereditary neoplastic syndrome
p.Thr210_Leu211insTer Multiple submitters hereditary neoplastic syndrome
p.Thr309fs Multiple submitters hereditary neoplastic syndrome
p.Thr603_Val604insTer Multiple submitters hereditary breast carcinoma
p.Trp146fs Multiple submitters hereditary breast carcinoma
p.Trp462Ter Multiple submitters hereditary breast carcinoma
p.Trp629Ter Multiple submitters hereditary breast carcinoma
p.Trp91Ter Multiple submitters hereditary neoplastic syndrome
p.Tyr404fs Multiple submitters hereditary neoplastic syndrome
p.Tyr404Ter Multiple submitters BARD1-related cancer predisposition
p.Tyr446Ter Multiple submitters hereditary breast carcinoma
p.Tyr492fs Multiple submitters hereditary neoplastic syndrome
p.Tyr492Ter Multiple submitters hereditary neoplastic syndrome
p.Tyr516Ter Multiple submitters hereditary breast carcinoma
p.Tyr597fs Multiple submitters hereditary breast carcinoma
p.Val154fs Multiple submitters hereditary breast carcinoma
p.Val298fs Multiple submitters hereditary neoplastic syndrome
p.Val477fs Multiple submitters hereditary breast carcinoma
p.Val510fs Multiple submitters hereditary breast carcinoma
p.Val531fs Multiple submitters hereditary neoplastic syndrome
p.Val61fs Multiple submitters hereditary neoplastic syndrome
c.1315-1G>A Single submitter
c.1396-13A>G Single submitter hereditary breast carcinoma
c.1569-?_*3030+?del Single submitter hereditary breast carcinoma
c.1678-5_1903+5del Single submitter hereditary breast carcinoma
c.1725_1903+740del Single submitter hereditary breast carcinoma
c.(1903+1_1904-1 Single submitter hereditary neoplastic syndrome
c.1904-2A>C Single submitter
c.2001+1G>T Single submitter hereditary breast carcinoma
p.Ala189fs Single submitter hereditary breast carcinoma
p.Ala195fs Single submitter hereditary breast carcinoma
p.Ala23fs Single submitter hereditary neoplastic syndrome
p.Ala262fs Single submitter hereditary breast carcinoma
p.Ala283fs Single submitter hereditary neoplastic syndrome
p.Ala35fs Single submitter hereditary breast carcinoma
p.Ala39fs Single submitter hereditary neoplastic syndrome
p.Ala554fs Single submitter hereditary neoplastic syndrome
p.Ala638fs Single submitter hereditary breast carcinoma
p.Ala721fs Single submitter hereditary breast carcinoma
p.Ala90fs Single submitter hereditary neoplastic syndrome
p.Arg129fs Single submitter hereditary breast carcinoma
p.Arg13fs Single submitter hereditary breast carcinoma
p.Arg15fs Single submitter hereditary breast carcinoma
p.Arg201fs Single submitter hereditary breast carcinoma
p.Arg201Ter Single submitter hereditary breast carcinoma
p.Arg327_Leu328delinsThrTer Single submitter hereditary neoplastic syndrome
p.Arg335fs Single submitter hereditary neoplastic syndrome
p.Arg370fs Single submitter hereditary breast ovarian cancer syndrome
p.Arg49fs Single submitter hereditary breast carcinoma
p.Arg566fs Single submitter hereditary breast carcinoma
p.Arg8fs Single submitter hereditary breast carcinoma
p.Asn138fs Single submitter hereditary breast carcinoma
p.Asn18fs Single submitter hereditary neoplastic syndrome
p.Asn219_Leu220insTer Single submitter hereditary breast carcinoma
p.Asn295fs Single submitter hereditary breast carcinoma
p.Asn318fs Single submitter hereditary neoplastic syndrome
p.Asn326fs Single submitter hereditary breast carcinoma
p.Asn380fs Single submitter hereditary breast carcinoma
p.Asn419fs Single submitter hereditary breast carcinoma
p.Asn494fs Single submitter hereditary neoplastic syndrome
p.Asn9fs Single submitter hereditary breast carcinoma
p.Asp259fs Single submitter hereditary breast carcinoma
p.Asp346fs Single submitter hereditary breast carcinoma
p.Asp3fs Single submitter hereditary breast carcinoma
p.Asp535fs Single submitter hereditary breast carcinoma
p.Asp612Ter Single submitter hereditary breast carcinoma
p.Asp710fs Single submitter hereditary breast carcinoma
p.Asp727fs Single submitter hereditary breast carcinoma
p.Asp94_Leu95insTer Single submitter hereditary breast carcinoma
p.Cys108fs Single submitter hereditary breast carcinoma
p.Cys271Ter Single submitter hereditary breast carcinoma
p.Cys50Ter Single submitter hereditary breast carcinoma
p.Cys620fs Single submitter hereditary breast carcinoma
p.Cys62fs Single submitter hereditary breast carcinoma
p.Cys74_Asp77delinsTer Single submitter hereditary breast carcinoma
p.Cys743fs Single submitter hereditary breast carcinoma
p.Cys78Ter Single submitter hereditary breast carcinoma
p.Cys86fs Single submitter hereditary neoplastic syndrome
p.Gln11fs Single submitter hereditary breast carcinoma
p.Gln206fs Single submitter hereditary breast carcinoma
p.Gln206Ter Single submitter hereditary breast carcinoma
p.Gln285fs Single submitter hereditary breast carcinoma
p.Gln482fs Single submitter hereditary breast carcinoma
p.Gln581Ter Single submitter hereditary breast carcinoma
p.Gln647Ter Single submitter hereditary breast carcinoma
p.Gln735fs Single submitter hereditary breast carcinoma
p.Glu125Ter Single submitter hereditary neoplastic syndrome
p.Glu181fs Single submitter hereditary breast carcinoma
p.Glu181Ter Single submitter hereditary breast carcinoma
p.Glu228fs Single submitter hereditary breast carcinoma
p.Glu228Ter Single submitter hereditary breast carcinoma
p.Glu233Ter Single submitter hereditary breast carcinoma
p.Glu268Ter Single submitter hereditary breast carcinoma
p.Glu277Ter Single submitter hereditary breast carcinoma
p.Glu287Ter Single submitter hereditary breast carcinoma
p.Glu296fs Single submitter hereditary breast carcinoma
p.Glu445fs Single submitter hereditary neoplastic syndrome
p.Glu547fs Single submitter hereditary breast carcinoma
p.Glu550fs Single submitter hereditary neoplastic syndrome
p.Glu550Ter Single submitter hereditary breast carcinoma
p.Glu587Ter Single submitter hereditary breast carcinoma
p.Glu599fs Single submitter hereditary breast carcinoma
p.Glu646Ter Single submitter hereditary breast carcinoma
p.Glu649fs Single submitter hereditary breast carcinoma
p.Glu67fs Single submitter hereditary breast carcinoma
p.Gly17fs Single submitter hereditary breast carcinoma
p.Gly227_Glu228insTer Single submitter hereditary breast carcinoma
p.Gly323fs Single submitter hereditary breast carcinoma
p.Gly32fs Single submitter hereditary breast carcinoma
p.Gly568Ter Single submitter hereditary breast carcinoma
p.Gly64Ter Single submitter hereditary neoplastic syndrome
p.Gly65fs Single submitter hereditary neoplastic syndrome
p.His36fs Single submitter hereditary neoplastic syndrome
p.His426fs Single submitter hereditary breast carcinoma
p.His556fs Single submitter hereditary neoplastic syndrome
p.Ile214fs Single submitter hereditary breast carcinoma
p.Ile249fs Single submitter hereditary breast carcinoma
p.Ile357fs Single submitter hereditary breast carcinoma
p.Ile573fs Single submitter hereditary breast carcinoma
p.Leu114fs Single submitter hereditary neoplastic syndrome
p.Leu114Ter Single submitter hereditary breast carcinoma
p.Leu132fs Single submitter hereditary neoplastic syndrome
p.Leu211_Ala212delinsTer Single submitter hereditary neoplastic syndrome
p.Leu211fs Single submitter hereditary breast carcinoma
p.Leu260Ter Single submitter hereditary breast carcinoma
p.Leu261fs Single submitter hereditary breast carcinoma
p.Leu275Ter Single submitter hereditary neoplastic syndrome
p.Leu316_Glu317delinsTer Single submitter hereditary neoplastic syndrome
p.Leu390fs Single submitter hereditary breast carcinoma
p.Leu416fs Single submitter hereditary breast carcinoma
p.Leu447fs Single submitter hereditary breast carcinoma
p.Leu448Ter Single submitter hereditary breast carcinoma
p.Leu479Ter Single submitter BARD1-related cancer predisposition
p.Leu512fs Single submitter hereditary breast carcinoma
p.Leu513fs Single submitter hereditary neoplastic syndrome
p.Leu514fs Single submitter hereditary neoplastic syndrome
p.Leu543fs Single submitter hereditary breast carcinoma
p.Leu577fs Single submitter hereditary breast carcinoma
p.Leu618fs Single submitter hereditary breast carcinoma
p.Leu618Ter Single submitter hereditary neoplastic syndrome
p.Leu63Ter Single submitter hereditary breast carcinoma
p.Lys124fs Single submitter hereditary breast carcinoma
p.Lys144fs Single submitter hereditary neoplastic syndrome
p.Lys196delinsLeuTer Single submitter hereditary breast ovarian cancer syndrome
p.Lys197fs Single submitter hereditary breast carcinoma
p.Lys197Ter Single submitter hereditary breast carcinoma
p.Lys232fs Single submitter hereditary neoplastic syndrome
p.Lys238fs Single submitter hereditary neoplastic syndrome
p.Lys302Ter Single submitter hereditary neoplastic syndrome
p.Lys312Ter Single submitter hereditary breast carcinoma
p.Lys334Ter Single submitter hereditary neoplastic syndrome
p.Lys369fs Single submitter hereditary breast carcinoma
p.Lys379Ter Single submitter BARD1-related cancer predisposition
p.Lys484Ter Single submitter hereditary breast carcinoma
p.Lys511Ter Single submitter hereditary breast carcinoma
p.Lys583fs Single submitter hereditary breast carcinoma
p.Lys593delinsPhePhePhePhePhePheXaaXaaXaaXaaLeuAspLeuLeuThrSerTer Single submitter hereditary breast carcinoma
p.Lys619fs Single submitter hereditary breast carcinoma
p.Lys96Ter Single submitter hereditary breast carcinoma
p.Met145fs Single submitter hereditary breast carcinoma
p.Met383fs Single submitter hereditary breast carcinoma
p.Met621fs Single submitter hereditary neoplastic syndrome
p.Met768Ter Single submitter hereditary breast carcinoma
p.Phe133fs Single submitter hereditary breast carcinoma
p.Phe229fs Single submitter hereditary breast carcinoma
p.Phe387fs Single submitter hereditary breast carcinoma
p.Phe526fs Single submitter hereditary neoplastic syndrome
p.Phe600Ter Single submitter hereditary breast carcinoma
p.Pro12fs Single submitter hereditary breast carcinoma
p.Pro187fs Single submitter hereditary neoplastic syndrome
p.Pro28fs Single submitter hereditary breast carcinoma
p.Pro2fs Single submitter hereditary neoplastic syndrome
p.Pro315_Leu316insTer Single submitter hereditary breast carcinoma
p.Pro411_Ser412insTer Single submitter hereditary breast carcinoma
p.Pro497fs Single submitter hereditary breast carcinoma
p.Ser103fs Single submitter hereditary breast carcinoma
p.Ser131fs Single submitter hereditary breast ovarian cancer syndrome
p.Ser142Ter Single submitter hereditary breast carcinoma
p.Ser162Ter Single submitter hereditary neoplastic syndrome
p.Ser179fs Single submitter hereditary neoplastic syndrome
p.Ser184fs Single submitter hereditary breast carcinoma
p.Ser231fs Single submitter hereditary neoplastic syndrome
p.Ser244fs Single submitter hereditary breast carcinoma
p.Ser263fs Single submitter hereditary neoplastic syndrome
p.Ser329fs Single submitter hereditary breast carcinoma
p.Ser344fs Single submitter hereditary neoplastic syndrome
p.Ser367fs Single submitter hereditary neoplastic syndrome
p.Ser37fs Single submitter hereditary breast carcinoma
p.Ser389fs Single submitter hereditary breast carcinoma
p.Ser391fs Single submitter hereditary breast carcinoma
p.Ser397fs Single submitter hereditary neoplastic syndrome
p.Ser400fs Single submitter hereditary neoplastic syndrome
p.Ser401_Ser402insTer Single submitter hereditary neoplastic syndrome
p.Ser410fs Single submitter hereditary breast carcinoma
p.Ser412fs Single submitter hereditary neoplastic syndrome
p.Ser412Ter Single submitter hereditary breast carcinoma
p.Ser51Ter Single submitter hereditary neoplastic syndrome
p.Ser558Ter Single submitter hereditary breast carcinoma
p.Ser578fs Single submitter hereditary breast carcinoma
p.Ser579Ter Single submitter hereditary breast carcinoma
p.Ser760fs Single submitter hereditary breast carcinoma
p.Thr299fs Single submitter hereditary breast carcinoma

Pathogenic/Likely pathogenic 89

c.1314+1G>A Multiple submitters hereditary neoplastic syndrome
c.1569-1G>C Multiple submitters hereditary breast carcinoma
c.159-1G>A Multiple submitters hereditary breast carcinoma
c.159-1G>T Multiple submitters hereditary breast ovarian cancer syndrome
c.159-2A>C Multiple submitters hereditary breast carcinoma
c.1678-1G>A Multiple submitters hereditary breast carcinoma
c.1678-1G>T Multiple submitters hereditary neoplastic syndrome
c.1678-2A>G Multiple submitters hereditary neoplastic syndrome
c.1678-3C>G Multiple submitters hereditary neoplastic syndrome
c.1811-2A>G Multiple submitters hereditary neoplastic syndrome
c.1903+1G>A Multiple submitters hereditary breast carcinoma
c.1904-1G>A Multiple submitters hereditary neoplastic syndrome
c.216-1G>T Multiple submitters hereditary breast carcinoma
p.Ala413_Met414insTer Multiple submitters hereditary neoplastic syndrome
p.Arg112Ter Multiple submitters Autosomal dominant BARD1-related disorders
p.Arg194fs Multiple submitters hereditary neoplastic syndrome
p.Arg406Ter Multiple submitters hereditary neoplastic syndrome
p.Arg641Ter Multiple submitters BARD1-related cancer predisposition
p.Asn450fs Multiple submitters hereditary breast ovarian cancer syndrome
p.Asn744Ter Multiple submitters hereditary neoplastic syndrome
p.Asp673fs Multiple submitters hereditary neoplastic syndrome
p.Asp77fs Multiple submitters hereditary breast carcinoma
p.Cys469Ter Multiple submitters hereditary breast carcinoma
p.Cys53fs Multiple submitters hereditary breast carcinoma
p.Cys645_Glu652delinsTer Multiple submitters hereditary breast carcinoma
p.Cys675fs Multiple submitters hereditary breast carcinoma
p.Cys71Tyr Multiple submitters hereditary breast carcinoma
p.Gln100Ter Multiple submitters BARD1-related cancer predisposition
p.Gln164Ter Multiple submitters hereditary neoplastic syndrome
p.Gln449fs Multiple submitters hereditary breast carcinoma
p.Gln449Ter Multiple submitters hereditary breast ovarian cancer syndrome
p.Gln493_Asn494insTer Multiple submitters hereditary breast carcinoma
p.Gln615fs Multiple submitters hereditary neoplastic syndrome
p.Gln666Ter Multiple submitters hereditary neoplastic syndrome
p.Gln701_Ile702insTer Multiple submitters hereditary breast carcinoma
p.Gln715Ter Multiple submitters hereditary neoplastic syndrome
p.Gln730Ter Multiple submitters hereditary neoplastic syndrome
p.Glu19Ter Multiple submitters hereditary breast carcinoma
p.Glu225fs Multiple submitters hereditary neoplastic syndrome
p.Glu27Ter Multiple submitters hereditary neoplastic syndrome
p.Glu287fs Multiple submitters hereditary neoplastic syndrome
p.Glu317fs Multiple submitters hereditary neoplastic syndrome
p.Glu386Ter Multiple submitters hereditary breast carcinoma
p.Glu429fs Multiple submitters hereditary neoplastic syndrome
p.Glu45Ter Multiple submitters hereditary neoplastic syndrome
p.Glu59fs Multiple submitters hereditary breast carcinoma
p.Glu652fs Multiple submitters BARD1-related cancer predisposition
p.Glu748Ter Multiple submitters hereditary breast carcinoma
p.Gly203fs Multiple submitters hereditary neoplastic syndrome
p.Gly674Ter Multiple submitters hereditary neoplastic syndrome
p.His686fs Multiple submitters hereditary breast carcinoma
p.Ile717fs Multiple submitters hereditary breast carcinoma
p.Leu211Ter Multiple submitters hereditary breast carcinoma
p.Leu239fs Multiple submitters hereditary neoplastic syndrome
p.Leu280fs Multiple submitters hereditary breast carcinoma
p.Leu399Ter Multiple submitters hereditary neoplastic syndrome
p.Leu625fs Multiple submitters hereditary neoplastic syndrome
p.Leu679Ter Multiple submitters hereditary neoplastic syndrome
p.Lys110Ter Multiple submitters hereditary neoplastic syndrome
p.Lys208fs Multiple submitters hereditary breast carcinoma
p.Lys684Ter Multiple submitters hereditary neoplastic syndrome
p.Met408fs Multiple submitters hereditary neoplastic syndrome
p.Phe732fs Multiple submitters hereditary neoplastic syndrome
p.Pro657fs Multiple submitters hereditary neoplastic syndrome
p.Ser121Ter Multiple submitters hereditary breast carcinoma
p.Ser174fs Multiple submitters hereditary breast ovarian cancer syndrome
p.Ser247fs Multiple submitters hereditary neoplastic syndrome
p.Ser288fs Multiple submitters hereditary neoplastic syndrome
p.Ser354Ter Multiple submitters hereditary neoplastic syndrome
p.Ser391Ter Multiple submitters hereditary neoplastic syndrome
p.Ser402Ter Multiple submitters hereditary neoplastic syndrome
p.Ser515fs Multiple submitters hereditary neoplastic syndrome
p.Ser553Ter Multiple submitters hereditary breast ovarian cancer syndrome
p.Ser579fs Multiple submitters hereditary breast carcinoma
p.Ser586fs Multiple submitters hereditary neoplastic syndrome
p.Trp218Ter Multiple submitters breast neoplasm
p.Trp34Ter Multiple submitters hereditary neoplastic syndrome
p.Trp635Ter Multiple submitters hereditary neoplastic syndrome
p.Trp680fs Multiple submitters hereditary neoplastic syndrome
p.Trp756Ter Multiple submitters BARD1-related cancer predisposition
p.Trp762Ter Multiple submitters hereditary breast carcinoma
p.Tyr736Ter Multiple submitters hereditary neoplastic syndrome
p.Tyr739fs Multiple submitters hereditary breast carcinoma
p.Val422fs Multiple submitters hereditary breast carcinoma
p.Val444fs Multiple submitters hereditary neoplastic syndrome
p.Val644_Cys645insTer Multiple submitters hereditary neoplastic syndrome
p.Val755_Trp756insTer Multiple submitters hereditary neoplastic syndrome
p.Val755fs Multiple submitters hereditary breast carcinoma
p.Val767fs Multiple submitters BARD1-related cancer predisposition

Likely pathogenic 114

c.1306_1314+7del Multiple submitters hereditary neoplastic syndrome
c.1314+1G>T Multiple submitters hereditary neoplastic syndrome
c.1395+1dup Multiple submitters hereditary neoplastic syndrome
c.1396-1G>A Multiple submitters hereditary breast carcinoma
c.1396-1G>C Multiple submitters hereditary neoplastic syndrome
c.1396-1G>T Multiple submitters hereditary neoplastic syndrome
c.1396-2A>C Multiple submitters hereditary breast carcinoma
c.1568+1G>A Multiple submitters hereditary breast carcinoma
c.1568+1G>T Multiple submitters hereditary neoplastic syndrome
c.1568+2T>C Multiple submitters hereditary neoplastic syndrome
c.1569-1G>A Multiple submitters hereditary breast carcinoma
c.1569-2A>G Multiple submitters hereditary breast carcinoma
c.158+1G>C Multiple submitters hereditary neoplastic syndrome
c.158+1G>T Multiple submitters hereditary breast carcinoma
c.158+2_158+10del Multiple submitters hereditary neoplastic syndrome
c.158+2T>G Multiple submitters hereditary neoplastic syndrome
c.1676_1677+23del Multiple submitters hereditary neoplastic syndrome
c.1677+1G>A Multiple submitters hereditary neoplastic syndrome
c.1677+1G>C Multiple submitters hereditary breast carcinoma
c.1677+1G>T Multiple submitters hereditary breast carcinoma
c.1677+2T>A Multiple submitters hereditary neoplastic syndrome
c.1678-1_1678del Multiple submitters hereditary neoplastic syndrome
c.1678-2A>T Multiple submitters hereditary breast carcinoma
c.1810+1G>A Multiple submitters hereditary neoplastic syndrome
c.1810+2T>G Multiple submitters hereditary breast carcinoma
c.1811-1G>A Multiple submitters hereditary breast ovarian cancer syndrome
c.1865_1903+274del Multiple submitters hereditary neoplastic syndrome
c.1903+1G>T Multiple submitters hereditary breast carcinoma
c.1903+2T>C Multiple submitters hereditary neoplastic syndrome
c.2001+1G>A Multiple submitters BARD1-related cancer predisposition
c.2001+1G>C Multiple submitters hereditary breast carcinoma
c.215+1G>A Multiple submitters hereditary neoplastic syndrome
c.215+2T>C Multiple submitters hereditary neoplastic syndrome
c.216-2A>G Multiple submitters hereditary neoplastic syndrome
c.364+1G>A Multiple submitters hereditary neoplastic syndrome
c.365-1G>T Multiple submitters hereditary neoplastic syndrome
p.Arg705Ter Multiple submitters hereditary breast carcinoma
p.Asp689fs Multiple submitters hereditary neoplastic syndrome
p.Gln701fs Multiple submitters hereditary neoplastic syndrome
p.Gln701Ter Multiple submitters BARD1-related cancer predisposition
p.Gln735Ter Multiple submitters hereditary breast ovarian cancer syndrome
p.Lys754fs Multiple submitters hereditary neoplastic syndrome
c.1307_1314+11del Single submitter hereditary breast carcinoma
c.1565_1568+298del Single submitter hereditary breast carcinoma
c.1568+2del Single submitter hereditary neoplastic syndrome
c.1569-2A>C Single submitter hereditary breast carcinoma
c.158+1_158+3delinsTT Single submitter hereditary breast carcinoma
c.158+1G>A Single submitter hereditary breast carcinoma
c.159-14A>G Single submitter hereditary neoplastic syndrome
c.159-2_159-1del Single submitter hereditary breast carcinoma
c.1676_1677+2del Single submitter hereditary neoplastic syndrome
c.1677+2del Single submitter hereditary breast carcinoma
c.1677+2T>C Single submitter hereditary breast carcinoma
c.1678-1_1684del Single submitter hereditary breast carcinoma
c.1678-1G>C Single submitter hereditary breast ovarian cancer syndrome
c.1678-24_1678-23insAATATAAAA Single submitter hereditary neoplastic syndrome
c.1678-2A>C Single submitter hereditary neoplastic syndrome
c.1764_1765insALU Single submitter hereditary neoplastic syndrome
c.1776_1777insL1 Single submitter hereditary neoplastic syndrome
c.1810+1_1810+32del Single submitter hereditary breast carcinoma
c.1903+1del Single submitter hereditary breast carcinoma
c.1903+1G>C Single submitter hereditary breast carcinoma
c.1903+2T>A Single submitter hereditary neoplastic syndrome
c.1914_2001+77del Single submitter hereditary breast carcinoma
c.1934_2001+52del Single submitter hereditary neoplastic syndrome
c.2002-15_2003del Single submitter hereditary neoplastic syndrome
c.215+2T>A Single submitter hereditary breast carcinoma
c.363_364+1del Single submitter hereditary breast carcinoma
c.364+1G>T Single submitter hereditary breast carcinoma
c.364+2T>G Single submitter hereditary breast carcinoma
c.365-20_365-1delinsAA Single submitter hereditary neoplastic syndrome
c.365-24_371del Single submitter hereditary breast carcinoma
c.365-2A>T Single submitter hereditary breast carcinoma
c.365-3315_793del Single submitter hereditary breast carcinoma
c.924_925insALU Single submitter hereditary neoplastic syndrome
p.Ala485fs Single submitter hereditary breast carcinoma
p.Arg520fs Single submitter hereditary breast carcinoma
p.Asn382fs Single submitter hereditary breast carcinoma
p.Asn73fs Single submitter hereditary breast carcinoma
p.Asp567fs Single submitter hereditary breast carcinoma
p.Asp712fs Single submitter hereditary neoplastic syndrome
p.Asp765fs Single submitter hereditary neoplastic syndrome
p.Cys639fs Single submitter hereditary breast carcinoma
p.Glu445Ter Single submitter
p.Glu740Ter Single submitter hereditary breast carcinoma
p.Gly700fs Single submitter hereditary breast carcinoma
p.His746fs Single submitter hereditary breast carcinoma
p.Ile441fs Single submitter
p.Ile653fs Single submitter hereditary neoplastic syndrome
p.Ile692fs Single submitter hereditary neoplastic syndrome
p.Leu220fs Single submitter hereditary breast carcinoma
p.Leu694fs Single submitter hereditary breast carcinoma
p.Lys292Ter Single submitter hereditary breast carcinoma
p.Lys334fs Single submitter hereditary breast carcinoma
p.Lys423Ter Single submitter hereditary breast carcinoma
p.Lys693Ter Single submitter hereditary breast carcinoma
p.Lys706Ter Single submitter hereditary neoplastic syndrome
p.Lys708fs Single submitter hereditary breast carcinoma
p.Met768fs Single submitter hereditary neoplastic syndrome
p.Pro654fs Single submitter hereditary neoplastic syndrome
p.Ser660fs Single submitter hereditary neoplastic syndrome
p.Ser704fs Single submitter hereditary breast carcinoma
p.Ser760Ter Single submitter hereditary breast carcinoma
p.Thr165fs Single submitter hereditary breast carcinoma
p.Thr291fs Single submitter hereditary breast carcinoma
p.Thr716fs Single submitter hereditary breast carcinoma
p.Trp756fs Single submitter BARD1-related cancer predisposition
p.Tyr678Ter Single submitter hereditary neoplastic syndrome
p.Tyr722Ter Single submitter hereditary breast carcinoma
p.Tyr739Ter Single submitter hereditary breast carcinoma
p.Tyr745Ter Single submitter hereditary breast carcinoma
p.Val720fs Single submitter hereditary breast carcinoma
p.Glu649_Glu655del No assertion criteria plasma cell myeloma
p.Lys438Asn No assertion criteria ovarian neoplasm ⚠

Conflicting classifications of pathogenicity 403

Showing the top 300 by review status; the full set is in the sitemap.

c.1314+14T>C Single submitter hereditary breast carcinoma
c.1314+4G>A Single submitter hereditary neoplastic syndrome
c.1315-19_1315-18inv Single submitter hereditary breast carcinoma
c.1315-2A>G Single submitter hereditary neoplastic syndrome ⚠
c.1395+17_1395+20del Single submitter hereditary breast carcinoma
c.1395+4G>A Single submitter hereditary breast carcinoma
c.1395+4G>T Single submitter hereditary neoplastic syndrome
c.1396-10A>G Single submitter hereditary neoplastic syndrome
c.1396-11A>G Single submitter hereditary neoplastic syndrome
c.1396-14A>G Single submitter hereditary neoplastic syndrome
c.1396-22_1396-19del Single submitter hereditary neoplastic syndrome
c.1396-5_1396-2del Single submitter hereditary neoplastic syndrome ⚠
c.1396-5A>G Single submitter hereditary neoplastic syndrome
c.1396-5A>T Single submitter hereditary neoplastic syndrome
c.1396-8T>G Single submitter hereditary breast carcinoma
c.1568+10T>G Single submitter hereditary breast carcinoma
c.1568+15G>T Single submitter hereditary neoplastic syndrome
c.1568+2dup Single submitter hereditary neoplastic syndrome ⚠
c.1568+3A>G Single submitter hereditary neoplastic syndrome
c.1568+5G>A Single submitter hereditary breast carcinoma
c.1569-13C>G Single submitter hereditary neoplastic syndrome
c.1569-7T>G Single submitter hereditary breast ovarian cancer syndrome
c.158+5A>G Single submitter hereditary breast carcinoma
c.158+6G>A Single submitter hereditary neoplastic syndrome
c.158+6G>T Single submitter hereditary neoplastic syndrome
c.1677+5G>A Single submitter BARD1-related cancer predisposition
c.1678-9T>G Single submitter hereditary breast carcinoma
c.1810+3G>A Single submitter hereditary breast carcinoma
c.1810+3G>T Single submitter hereditary neoplastic syndrome
c.1811-10_1811-2del Single submitter hereditary neoplastic syndrome ⚠
c.1811-1G>C Single submitter hereditary neoplastic syndrome ⚠
c.1903+16G>C Single submitter hereditary neoplastic syndrome
c.1904-10T>C Single submitter hereditary breast carcinoma
c.1904-10T>G Single submitter hereditary breast carcinoma
c.1904-12T>G Single submitter hereditary breast carcinoma
c.1904-17T>A Single submitter hereditary neoplastic syndrome
c.1904-1G>T Single submitter hereditary neoplastic syndrome ⚠
c.1904-2_1904-1del Single submitter hereditary breast carcinoma ⚠
c.1904-2A>T Single submitter hereditary neoplastic syndrome ⚠
c.1904-2del Single submitter hereditary neoplastic syndrome ⚠
c.1904-3C>G Single submitter hereditary neoplastic syndrome
c.1904-3C>T Single submitter hereditary neoplastic syndrome
c.1904-5G>A Single submitter hereditary neoplastic syndrome
c.1904-5G>C Single submitter hereditary neoplastic syndrome
c.1904-5G>T Single submitter hereditary neoplastic syndrome
c.2001+10T>C Single submitter hereditary neoplastic syndrome
c.2001+2T>C Single submitter hereditary neoplastic syndrome ⚠
c.2001+3A>G Single submitter hereditary neoplastic syndrome
c.2002-12T>G Single submitter Hereditary cancer
c.2002-1G>A Single submitter hereditary neoplastic syndrome ⚠
c.2002-1G>C Single submitter hereditary breast carcinoma ⚠
c.2002-1G>T Single submitter hereditary breast ovarian cancer syndrome ⚠
c.2002-2A>C Single submitter hereditary breast carcinoma ⚠
c.2002-2A>G Single submitter hereditary breast ovarian cancer syndrome ⚠
c.2002-2A>T Single submitter hereditary neoplastic syndrome ⚠
c.215+12C>T Single submitter Breast and/or ovarian cancer
c.215+13G>A Single submitter hereditary neoplastic syndrome
c.215+5_215+8del Single submitter hereditary neoplastic syndrome
c.215+9T>G Single submitter hereditary breast carcinoma
c.216-10T>C Single submitter hereditary breast carcinoma
c.216-14T>C Single submitter hereditary neoplastic syndrome
c.216-16T>A Single submitter hereditary breast carcinoma
c.216-1G>A Single submitter hereditary breast carcinoma ⚠
c.216-1G>C Single submitter hereditary neoplastic syndrome ⚠
c.216-3A>C Single submitter hereditary neoplastic syndrome
c.216-3A>T Single submitter hereditary breast ovarian cancer syndrome
c.216-6T>A Single submitter hereditary neoplastic syndrome
c.216-8_216-4del Single submitter hereditary breast carcinoma
c.216-8T>C Single submitter hereditary neoplastic syndrome
c.364+7A>C Single submitter hereditary breast carcinoma
c.364+7A>G Single submitter hereditary breast carcinoma
c.365-14dup Single submitter hereditary neoplastic syndrome
c.365-5G>A Single submitter hereditary neoplastic syndrome
c.-12G>T Single submitter hereditary neoplastic syndrome
c.-4G>A Single submitter Hereditary cancer
p.4_8NRQPR[1] Single submitter BARD1-related cancer predisposition
p.Ala168Glu Single submitter hereditary breast carcinoma ⚠
p.Ala168Gly Single submitter hereditary neoplastic syndrome ⚠
p.Ala168Val Single submitter hereditary neoplastic syndrome ⚠
p.Ala173Thr Single submitter hereditary neoplastic syndrome ⚠
p.Ala173Val Single submitter hereditary neoplastic syndrome ⚠
p.Ala189Thr Single submitter hereditary neoplastic syndrome ⚠
p.Ala189Val Single submitter hereditary neoplastic syndrome ⚠
p.Ala198Ser Single submitter hereditary neoplastic syndrome ⚠
p.Ala222Ser Single submitter hereditary neoplastic syndrome ⚠
p.Ala222Thr Single submitter hereditary neoplastic syndrome ⚠
p.Ala222Val Single submitter hereditary neoplastic syndrome ⚠
p.Ala25Pro Single submitter BARD1-related cancer predisposition ⚠
p.Ala33Pro Single submitter BARD1-related cancer predisposition ⚠
p.Ala33Val Single submitter hereditary neoplastic syndrome ⚠
p.Ala35= Single submitter hereditary neoplastic syndrome
p.Ala40Val Single submitter hereditary neoplastic syndrome ⚠
p.Ala413Thr Single submitter hereditary neoplastic syndrome ⚠
p.Ala502Val Single submitter hereditary neoplastic syndrome ⚠
p.Ala613Glu Single submitter hereditary neoplastic syndrome ⚠
p.Ala638Thr Single submitter hereditary neoplastic syndrome ⚠
p.Arg112Gln Single submitter BARD1-related disorder ⚠
p.Arg155= Single submitter hereditary neoplastic syndrome
p.Arg194Lys Single submitter BARD1-related cancer predisposition ⚠
p.Arg21Pro Single submitter hereditary neoplastic syndrome ⚠
p.Arg322His Single submitter BARD1-related cancer predisposition ⚠
p.Arg370Cys Single submitter BARD1-related cancer predisposition ⚠
p.Arg370His Single submitter hereditary neoplastic syndrome ⚠
p.Arg370Leu Single submitter hereditary neoplastic syndrome ⚠
p.Arg406Gln Single submitter BARD1-related cancer predisposition ⚠
p.Arg406Gly Single submitter hereditary neoplastic syndrome ⚠
p.Arg529Gln Single submitter BARD1-related cancer predisposition ⚠
p.Arg529Trp Single submitter BARD1-related cancer predisposition ⚠
p.Arg565His Single submitter hereditary neoplastic syndrome ⚠
p.Arg58Lys Single submitter hereditary neoplastic syndrome ⚠
p.Arg641Gln Single submitter hereditary neoplastic syndrome ⚠
p.Arg642Gly Single submitter hereditary neoplastic syndrome ⚠
p.Arg642Thr Single submitter hereditary breast carcinoma ⚠
p.Arg658His Single submitter Hereditary cancer ⚠
p.Arg659= Single submitter Breast and/or ovarian cancer
p.Arg731Cys Single submitter BARD1-related cancer predisposition ⚠
p.Arg731Gly Single submitter Hereditary cancer ⚠
p.Arg731His Single submitter hereditary neoplastic syndrome ⚠
p.Arg749Lys Single submitter hereditary neoplastic syndrome ⚠
p.Asn118His Single submitter hereditary neoplastic syndrome ⚠
p.Asn118Ser Single submitter hereditary neoplastic syndrome ⚠
p.Asn134His Single submitter hereditary neoplastic syndrome ⚠
p.Asn134Thr Single submitter hereditary neoplastic syndrome ⚠
p.Asn18Lys Single submitter hereditary neoplastic syndrome ⚠
p.Asn215Ser Single submitter BARD1-related cancer predisposition ⚠
p.Asn219Ser Single submitter hereditary neoplastic syndrome ⚠
p.Asn255Ser Single submitter hereditary neoplastic syndrome ⚠
p.Asn295Ser Single submitter hereditary neoplastic syndrome ⚠
p.Asn318Asp Single submitter hereditary neoplastic syndrome ⚠
p.Asn319Ser Single submitter hereditary neoplastic syndrome ⚠
p.Asn326Asp Single submitter hereditary neoplastic syndrome ⚠
p.Asn326Ser Single submitter hereditary neoplastic syndrome ⚠
p.Asn356Ile Single submitter hereditary neoplastic syndrome ⚠
p.Asn356Lys Single submitter BARD1-related cancer predisposition ⚠
p.Asn419Asp Single submitter hereditary neoplastic syndrome ⚠
p.Asn419Ser Single submitter hereditary neoplastic syndrome ⚠
p.Asn470Ser Single submitter BARD1-related cancer predisposition ⚠
p.Asn55Asp Single submitter hereditary neoplastic syndrome ⚠
p.Asn626Ile Single submitter hereditary neoplastic syndrome ⚠
p.Asn626Ser Single submitter Breast and/or ovarian cancer ⚠
p.Asn663= Single submitter hereditary neoplastic syndrome
p.Asn718Ser Single submitter hereditary breast carcinoma ⚠
p.Asn73Asp Single submitter hereditary breast carcinoma ⚠
p.Asn98Ser Single submitter hereditary neoplastic syndrome ⚠
p.Asp102Asn Single submitter hereditary neoplastic syndrome ⚠
p.Asp122Asn Single submitter hereditary neoplastic syndrome ⚠
p.Asp126Ala Single submitter hereditary neoplastic syndrome ⚠
p.Asp172Asn Single submitter hereditary neoplastic syndrome ⚠
p.Asp190Asn Single submitter Breast and/or ovarian cancer ⚠
p.Asp190His Single submitter hereditary breast carcinoma ⚠
p.Asp190Tyr Single submitter hereditary neoplastic syndrome ⚠
p.Asp226His Single submitter hereditary neoplastic syndrome ⚠
p.Asp230Glu Single submitter hereditary neoplastic syndrome ⚠
p.Asp259Gly Single submitter BARD1-related cancer predisposition ⚠
p.Asp29Ala Single submitter hereditary breast carcinoma ⚠
p.Asp29Val Single submitter hereditary breast carcinoma ⚠
p.Asp346Asn Single submitter hereditary breast carcinoma ⚠
p.Asp385Asn Single submitter hereditary neoplastic syndrome ⚠
p.Asp601Gly Single submitter hereditary neoplastic syndrome ⚠
p.Asp612Val Single submitter Breast and/or ovarian cancer ⚠
p.Asp710Val Single submitter BARD1-related cancer predisposition ⚠
p.Asp727Asn Single submitter hereditary neoplastic syndrome ⚠
p.Asp727Glu Single submitter hereditary neoplastic syndrome ⚠
p.Asp765Asn Single submitter hereditary neoplastic syndrome ⚠
p.Cys336Tyr Single submitter hereditary neoplastic syndrome ⚠
p.Cys362Gly Single submitter hereditary neoplastic syndrome ⚠
p.Cys368Trp Single submitter hereditary neoplastic syndrome ⚠
p.Cys50= Single submitter hereditary breast carcinoma
p.Cys53= Single submitter Breast and/or ovarian cancer
p.Cys53Trp Single submitter hereditary neoplastic syndrome ⚠
p.Cys53Tyr Single submitter hereditary breast carcinoma ⚠
p.Cys71Ser Single submitter hereditary neoplastic syndrome ⚠
p.Cys743Arg Single submitter hereditary breast carcinoma ⚠
p.Cys83Arg Single submitter hereditary neoplastic syndrome ⚠
p.Gln11His Single submitter Breast and/or ovarian cancer ⚠
p.Gln206Arg Single submitter hereditary neoplastic syndrome ⚠
p.Gln206Lys Single submitter hereditary breast carcinoma ⚠
p.Gln216Arg Single submitter hereditary neoplastic syndrome ⚠
p.Gln237Glu Single submitter BARD1-related cancer predisposition ⚠
p.Gln245= Single submitter hereditary breast ovarian cancer syndrome
p.Gln449= Single submitter hereditary neoplastic syndrome
p.Gln449Arg Single submitter hereditary breast ovarian cancer syndrome ⚠
p.Gln6Ter Single submitter hereditary breast carcinoma ⚠
p.Gln752Arg Single submitter hereditary neoplastic syndrome ⚠
p.Gln93= Single submitter BARD1-related cancer predisposition
p.Gln93Arg Single submitter hereditary neoplastic syndrome ⚠
p.Glu119Lys Single submitter hereditary neoplastic syndrome ⚠
p.Glu193Lys Single submitter hereditary neoplastic syndrome ⚠
p.Glu213Lys Single submitter hereditary neoplastic syndrome ⚠
p.Glu223Gly Single submitter BARD1-related cancer predisposition ⚠
p.Glu228= Single submitter hereditary neoplastic syndrome
p.Glu270Gln Single submitter hereditary neoplastic syndrome ⚠
p.Glu27Gln Single submitter hereditary neoplastic syndrome ⚠
p.Glu287Val Single submitter hereditary neoplastic syndrome ⚠
p.Glu301= Single submitter hereditary neoplastic syndrome
p.Glu317Gln Single submitter hereditary neoplastic syndrome ⚠
p.Glu317Gly Single submitter hereditary breast carcinoma ⚠
p.Glu361Asp Single submitter hereditary neoplastic syndrome ⚠
p.Glu587Asp Single submitter hereditary neoplastic syndrome ⚠
p.Glu587Lys Single submitter hereditary neoplastic syndrome ⚠
p.Glu748Asp Single submitter hereditary neoplastic syndrome ⚠
p.Glu748Lys Single submitter hereditary neoplastic syndrome ⚠
p.Glu771Gln Single submitter hereditary neoplastic syndrome ⚠
p.Gly203Arg Single submitter hereditary neoplastic syndrome ⚠
p.Gly227Asp Single submitter hereditary neoplastic syndrome ⚠
p.Gly264= Single submitter hereditary breast carcinoma
p.Gly32Val Single submitter hereditary neoplastic syndrome ⚠
p.Gly373Asp Single submitter hereditary neoplastic syndrome ⚠
p.Gly374Asp Single submitter hereditary breast carcinoma ⚠
p.Gly439= Single submitter hereditary neoplastic syndrome
p.Gly491= Single submitter BARD1-related cancer predisposition
p.Gly65= Single submitter hereditary neoplastic syndrome
p.Gly698Val Single submitter hereditary neoplastic syndrome ⚠
p.Gly82Ala Single submitter hereditary neoplastic syndrome ⚠
p.Gly82Arg Single submitter hereditary neoplastic syndrome ⚠
p.Gly82Val Single submitter hereditary neoplastic syndrome ⚠
p.His116Tyr Single submitter hereditary neoplastic syndrome ⚠
p.His324Arg Single submitter hereditary neoplastic syndrome ⚠
p.His325Arg Single submitter hereditary neoplastic syndrome ⚠
p.His325Gln Single submitter hereditary neoplastic syndrome ⚠
p.His483Arg Single submitter BARD1-related cancer predisposition ⚠
p.His685Arg Single submitter hereditary neoplastic syndrome ⚠
p.His686Arg Single submitter hereditary neoplastic syndrome ⚠
p.His746Arg Single submitter hereditary neoplastic syndrome ⚠
p.Ile169Val Single submitter hereditary neoplastic syndrome ⚠
p.Ile249Val Single submitter hereditary breast carcinoma ⚠
p.Ile254Leu Single submitter hereditary neoplastic syndrome ⚠
p.Ile258Thr Single submitter BARD1-related cancer predisposition ⚠
p.Ile286Met Single submitter hereditary neoplastic syndrome ⚠
p.Ile332Val Single submitter hereditary neoplastic syndrome ⚠
p.Ile340Val Single submitter hereditary neoplastic syndrome ⚠
p.Ile357Thr Single submitter BARD1-related cancer predisposition ⚠
p.Ile357Val Single submitter hereditary breast carcinoma ⚠
p.Ile388Leu Single submitter hereditary breast ovarian cancer syndrome ⚠
p.Ile388Val Single submitter hereditary neoplastic syndrome ⚠
p.Ile434Phe Single submitter hereditary neoplastic syndrome ⚠
p.Ile441Val Single submitter hereditary neoplastic syndrome ⚠
p.Ile509Val Single submitter hereditary breast carcinoma ⚠
p.Ile573Thr Single submitter BARD1-related cancer predisposition ⚠
p.Ile692Leu Single submitter hereditary neoplastic syndrome ⚠
p.Ile692Thr Single submitter hereditary neoplastic syndrome ⚠
p.Ile692Val Single submitter hereditary neoplastic syndrome ⚠
p.Ile702Met Single submitter hereditary neoplastic syndrome ⚠
p.Ile702Thr Single submitter hereditary breast carcinoma ⚠
p.Ile702Val Single submitter hereditary neoplastic syndrome ⚠
p.Ile717= Single submitter hereditary neoplastic syndrome
p.Ile764fs Single submitter hereditary neoplastic syndrome ⚠
p.Ile764Thr Single submitter BARD1-related disorder ⚠
p.Leu132Val Single submitter hereditary neoplastic syndrome ⚠
p.Leu220Ser Single submitter hereditary neoplastic syndrome ⚠
p.Leu239Gln Single submitter Breast and/or ovarian cancer ⚠
p.Leu261= Single submitter Breast and/or ovarian cancer
p.Leu266Phe Single submitter hereditary breast carcinoma ⚠
p.Leu316Val Single submitter hereditary neoplastic syndrome ⚠
p.Leu359Phe Single submitter hereditary neoplastic syndrome ⚠
p.Leu390Ile Single submitter hereditary breast carcinoma ⚠
p.Leu416Arg Single submitter hereditary neoplastic syndrome ⚠
p.Leu447Val Single submitter BARD1-related cancer predisposition ⚠
p.Leu465= Single submitter hereditary neoplastic syndrome
p.Leu513Ter Single submitter hereditary breast carcinoma ⚠
p.Leu572Phe Single submitter hereditary neoplastic syndrome ⚠
p.Leu618Met Single submitter hereditary breast carcinoma ⚠
p.Leu622Phe Single submitter hereditary neoplastic syndrome ⚠
p.Leu668Ter Single submitter hereditary neoplastic syndrome ⚠
p.Leu694= Single submitter hereditary neoplastic syndrome
p.Leu742Met Single submitter hereditary breast carcinoma ⚠
p.Leu742Phe Single submitter hereditary neoplastic syndrome ⚠
p.Leu742Val Single submitter hereditary breast carcinoma ⚠
p.Leu775Phe Single submitter hereditary breast carcinoma ⚠
p.Lys127Glu Single submitter hereditary neoplastic syndrome ⚠
p.Lys130Arg Single submitter hereditary neoplastic syndrome ⚠
p.Lys130Thr Single submitter hereditary breast carcinoma ⚠
p.Lys140Asn Single submitter hereditary neoplastic syndrome ⚠
p.Lys292Asn Single submitter hereditary neoplastic syndrome ⚠
p.Lys311Asn Single submitter BARD1-related disorder ⚠
p.Lys311Glu Single submitter hereditary neoplastic syndrome ⚠
p.Lys379Arg Single submitter hereditary neoplastic syndrome ⚠
p.Lys423Arg Single submitter hereditary breast carcinoma ⚠
p.Lys503Arg Single submitter hereditary breast carcinoma ⚠
p.Lys548= Single submitter hereditary breast carcinoma
p.Lys643Arg Single submitter hereditary neoplastic syndrome ⚠
p.Lys684Arg Single submitter hereditary neoplastic syndrome ⚠
p.Lys706Glu Single submitter BARD1-related cancer predisposition ⚠
p.Met104Val Single submitter hereditary breast carcinoma ⚠
p.Met1Ile Single submitter hereditary neoplastic syndrome ⚠
p.Met383Arg Single submitter hereditary breast carcinoma ⚠
p.Met383Ile Single submitter hereditary neoplastic syndrome ⚠
p.Met383Leu Single submitter hereditary neoplastic syndrome ⚠
p.Met383Lys Single submitter hereditary neoplastic syndrome ⚠
p.Met383Val Single submitter hereditary neoplastic syndrome ⚠
p.Met408Val Single submitter hereditary neoplastic syndrome ⚠
p.Met414Leu Single submitter hereditary neoplastic syndrome ⚠
p.Met414Val Single submitter hereditary breast carcinoma ⚠
p.Met420Thr Single submitter BARD1-related cancer predisposition ⚠
p.Met560Val Single submitter BARD1-related cancer predisposition ⚠
p.Phe229Leu Single submitter hereditary neoplastic syndrome ⚠
p.Phe242= Single submitter hereditary neoplastic syndrome
p.Phe272Leu Single submitter hereditary neoplastic syndrome ⚠
p.Phe347Ser Single submitter hereditary breast carcinoma ⚠
p.Phe387Leu Single submitter hereditary breast carcinoma ⚠

Benign 128

c.1315-19G>A Multiple submitters hereditary neoplastic syndrome
c.1568+14C>T Multiple submitters hereditary neoplastic syndrome
c.1568+42T>C Multiple submitters hereditary breast ovarian cancer syndrome
c.1568+51A>G Multiple submitters hereditary neoplastic syndrome
c.1568+81A>G Multiple submitters
c.1568+86C>A Multiple submitters
c.158+46A>C Multiple submitters hereditary breast ovarian cancer syndrome
c.159-70T>G Multiple submitters hereditary breast ovarian cancer syndrome
c.1677+89A>C Multiple submitters
c.1810+133C>A Multiple submitters
c.1811-242T>C Multiple submitters
c.1811-69T>C Multiple submitters hereditary breast ovarian cancer syndrome
c.1811-77A>G Multiple submitters hereditary breast ovarian cancer syndrome
c.1811-87C>G Multiple submitters hereditary breast ovarian cancer syndrome
c.1903+146T>C Multiple submitters
c.1903+221A>G Multiple submitters
c.1903+226G>T Multiple submitters
c.1903+287C>T Multiple submitters
c.1903+98C>T Multiple submitters
c.1904-280G>A Multiple submitters
c.2001+66A>C Multiple submitters hereditary breast ovarian cancer syndrome
c.215+105C>G Multiple submitters
c.215+132A>G Multiple submitters
c.215+68del Multiple submitters hereditary breast ovarian cancer syndrome
c.215+75A>G Multiple submitters hereditary breast ovarian cancer syndrome
c.-78G>A Multiple submitters hereditary neoplastic syndrome
c.*137_*138dup Multiple submitters hereditary breast carcinoma
c.*138del Multiple submitters hereditary breast carcinoma
c.*167A>G Multiple submitters
p.Arg378Ser Multiple submitters BARD1-related cancer predisposition
p.Glu580Lys Multiple submitters Breast and/or ovarian cancer
p.His506= Multiple submitters hereditary neoplastic syndrome
p.Thr351= Multiple submitters hereditary neoplastic syndrome
c.1314+149T>C Single submitter
c.1314+238G>A Single submitter
c.1314+254A>G Single submitter
c.1315-196T>C Single submitter
c.1315-200A>G Single submitter
c.1315-202C>T Single submitter
c.1395+17del Single submitter hereditary breast carcinoma
c.1396-15dup Single submitter hereditary breast carcinoma
c.1396-22_1396-20del Single submitter hereditary breast carcinoma
c.1396-251C>A Single submitter
c.1396-281T>A Single submitter
c.1568+158C>A Single submitter
c.1568+170_1568+171insTCTC Single submitter
c.1568+219T>C Single submitter
c.1568+274A>G Single submitter
c.1568+80_1568+81del Single submitter
c.1569-221A>G Single submitter
c.158+199G>A Single submitter
c.158+4280C>G Single submitter hereditary breast carcinoma
c.1677+326_1677+330del Single submitter
c.1677+93C>T Single submitter breast-ovarian cancer, familial, susceptibility to, 2
c.1678-11dup Single submitter hereditary breast carcinoma
c.1678-162T>A Single submitter
c.1678-199A>G Single submitter
c.1678-333C>T Single submitter
c.1811-10del Single submitter hereditary breast carcinoma
c.1811-3del Single submitter hereditary breast carcinoma
c.1903+24T>G Single submitter breast-ovarian cancer, familial, susceptibility to, 2
c.1904-208A>T Single submitter
c.1904-213G>T Single submitter
c.1904-6dup Single submitter hereditary breast carcinoma
c.2002-119C>G Single submitter
c.2002-139A>C Single submitter
c.2002-249A>G Single submitter
c.216-13_216-12del Single submitter hereditary breast carcinoma
c.216-316G>A Single submitter
c.216-37T>C Single submitter
c.364+129_364+130dup Single submitter
c.364+129dup Single submitter
c.365-21_365-18del Single submitter hereditary breast carcinoma
c.365-8insT Single submitter hereditary neoplastic syndrome
c.*119G>A Single submitter hereditary breast carcinoma
c.*122_*123del Single submitter hereditary breast carcinoma
c.*138dup Single submitter
c.*1A>G Single submitter hereditary breast carcinoma
c.*2T>A Single submitter hereditary breast carcinoma
p.Ala173= Single submitter hereditary breast carcinoma
p.Ala262= Single submitter hereditary breast carcinoma
p.Ala283= Single submitter hereditary breast carcinoma
p.Ala33= Single submitter hereditary breast carcinoma
p.Ala468= Single submitter hereditary breast carcinoma
p.Ala502= Single submitter hereditary breast carcinoma
p.Arg8= Single submitter hereditary breast carcinoma
p.Asn113= Single submitter hereditary breast carcinoma
p.Asn219= Single submitter hereditary breast carcinoma
p.Asn494= Single submitter hereditary breast carcinoma
p.Asp453= Single submitter hereditary breast carcinoma
p.Cys71= Single submitter hereditary breast carcinoma
p.Cys78= Single submitter hereditary breast carcinoma
p.Gln350_Thr351= Single submitter hereditary breast carcinoma
p.Glu221= Single submitter hereditary breast carcinoma
p.Glu317= Single submitter hereditary breast carcinoma
p.Gly256= Single submitter hereditary breast carcinoma
p.Gly373= Single submitter hereditary breast carcinoma
p.Gly611= Single submitter hereditary breast carcinoma
p.Gly627= Single submitter hereditary breast carcinoma
p.His483= Single submitter hereditary breast carcinoma
p.His686= Single submitter hereditary breast carcinoma
p.Ile525= Single submitter hereditary breast carcinoma
p.Ile737= Single submitter hereditary breast carcinoma
p.Ile738= Single submitter hereditary breast carcinoma
p.Leu101= Single submitter hereditary breast carcinoma
p.Leu44= Single submitter hereditary breast carcinoma
p.Leu47= Single submitter hereditary breast carcinoma
p.Leu486= Single submitter hereditary breast carcinoma
p.Lys321= Single submitter hereditary breast carcinoma
p.Lys415= Single submitter hereditary breast carcinoma
p.Lys670= Single submitter hereditary breast carcinoma
p.Pro149= Single submitter hereditary breast carcinoma
p.Pro365= Single submitter hereditary breast carcinoma
p.Pro610= Single submitter hereditary breast carcinoma
p.Pro7= Single submitter hereditary breast carcinoma
p.Ser103= Single submitter hereditary breast carcinoma
p.Ser142= Single submitter hereditary breast carcinoma
p.Ser247= Single submitter hereditary breast carcinoma
p.Ser265= Single submitter hereditary breast carcinoma
p.Ser293= Single submitter hereditary breast carcinoma
p.Ser558= Single submitter hereditary breast carcinoma
p.Ser704= Single submitter hereditary breast carcinoma
p.Ser711= Single submitter hereditary breast carcinoma
p.Ser728= Single submitter hereditary breast carcinoma
p.Thr394= Single submitter hereditary breast carcinoma
p.Thr617= Single submitter hereditary breast carcinoma
p.Val422= Single submitter hereditary breast carcinoma
p.Val444= Single submitter hereditary breast carcinoma

Benign/Likely benign 361

Showing the top 300 by review status; the full set is in the sitemap.

c.1314+11T>G Multiple submitters hereditary neoplastic syndrome
c.1314+29C>G Multiple submitters hereditary breast ovarian cancer syndrome
c.1315-168C>T Multiple submitters
c.1315-5del Multiple submitters hereditary breast carcinoma
c.1396-27_1396-19del Multiple submitters hereditary breast carcinoma
c.1569-20dup Multiple submitters hereditary breast carcinoma
c.1569-56A>G Multiple submitters hereditary breast ovarian cancer syndrome
c.159-42A>C Multiple submitters hereditary breast ovarian cancer syndrome
c.159-7C>T Multiple submitters hereditary neoplastic syndrome
c.1678-18C>G Multiple submitters hereditary neoplastic syndrome
c.1678-20A>G Multiple submitters hereditary neoplastic syndrome
c.1811-16dup Multiple submitters hereditary neoplastic syndrome
c.2002-11C>T Multiple submitters hereditary neoplastic syndrome
c.216-14del Multiple submitters hereditary neoplastic syndrome
c.216-15_216-14del Multiple submitters hereditary neoplastic syndrome
c.216-29dup Multiple submitters hereditary breast carcinoma
c.216-9A>T Multiple submitters hereditary neoplastic syndrome
c.364+16A>G Multiple submitters hereditary neoplastic syndrome
c.364+17T>C Multiple submitters hereditary neoplastic syndrome
c.365-14_365-13dup Multiple submitters hereditary neoplastic syndrome
c.365-16del Multiple submitters hereditary breast carcinoma
c.365-23T>A Multiple submitters breast-ovarian cancer, familial, susceptibility to, 2
c.365-7C>T Multiple submitters hereditary neoplastic syndrome
c.365-8del Multiple submitters hereditary neoplastic syndrome
c.-19T>C Multiple submitters hereditary neoplastic syndrome
c.-83C>T Multiple submitters hereditary breast ovarian cancer syndrome
c.*136_*138dup Multiple submitters hereditary breast carcinoma
p.Ala136= Multiple submitters hereditary neoplastic syndrome
p.Ala168= Multiple submitters hereditary neoplastic syndrome
p.Ala189= Multiple submitters hereditary neoplastic syndrome
p.Ala195= Multiple submitters hereditary neoplastic syndrome
p.Ala198= Multiple submitters hereditary neoplastic syndrome
p.Ala200= Multiple submitters hereditary neoplastic syndrome
p.Ala212= Multiple submitters hereditary neoplastic syndrome
p.Ala25= Multiple submitters hereditary neoplastic syndrome
p.Ala39= Multiple submitters hereditary neoplastic syndrome
p.Ala40= Multiple submitters hereditary neoplastic syndrome
p.Ala413= Multiple submitters hereditary breast carcinoma
p.Ala435= Multiple submitters hereditary breast carcinoma
p.Ala460= Multiple submitters hereditary neoplastic syndrome
p.Ala485= Multiple submitters hereditary neoplastic syndrome
p.Ala518= Multiple submitters hereditary neoplastic syndrome
p.Ala522= Multiple submitters hereditary neoplastic syndrome
p.Ala554= Multiple submitters hereditary neoplastic syndrome
p.Ala589= Multiple submitters hereditary neoplastic syndrome
p.Ala638= Multiple submitters hereditary neoplastic syndrome
p.Ala724= Multiple submitters hereditary neoplastic syndrome
p.Ala90= Multiple submitters hereditary neoplastic syndrome
p.Arg112= Multiple submitters hereditary neoplastic syndrome
p.Arg13= Multiple submitters hereditary breast carcinoma
p.Arg15= Multiple submitters hereditary neoplastic syndrome
p.Arg150= Multiple submitters hereditary breast carcinoma
p.Arg21= Multiple submitters hereditary neoplastic syndrome
p.Arg294= Multiple submitters hereditary neoplastic syndrome
p.Arg31= Multiple submitters hereditary breast carcinoma
p.Arg335= Multiple submitters hereditary neoplastic syndrome
p.Arg378= Multiple submitters hereditary neoplastic syndrome
p.Arg405= Multiple submitters hereditary breast carcinoma
p.Arg406= Multiple submitters hereditary breast carcinoma
p.Arg424= Multiple submitters hereditary neoplastic syndrome
p.Arg520= Multiple submitters hereditary neoplastic syndrome
p.Arg529= Multiple submitters hereditary neoplastic syndrome
p.Arg565= Multiple submitters hereditary breast carcinoma
p.Arg58= Multiple submitters hereditary breast carcinoma
p.Arg641= Multiple submitters hereditary breast carcinoma
p.Arg642= Multiple submitters hereditary neoplastic syndrome
p.Arg658= Multiple submitters hereditary neoplastic syndrome
p.Arg658Cys Multiple submitters Hereditary cancer ⚠
p.Arg661= Multiple submitters hereditary neoplastic syndrome
p.Arg749= Multiple submitters hereditary neoplastic syndrome
p.Arg99= Multiple submitters hereditary neoplastic syndrome
p.Asn118= Multiple submitters hereditary neoplastic syndrome
p.Asn141= Multiple submitters hereditary breast carcinoma
p.Asn18= Multiple submitters hereditary neoplastic syndrome
p.Asn215= Multiple submitters hereditary breast carcinoma
p.Asn255= Multiple submitters hereditary neoplastic syndrome
p.Asn295= Multiple submitters hereditary neoplastic syndrome
p.Asn306= Multiple submitters hereditary neoplastic syndrome
p.Asn318= Multiple submitters hereditary neoplastic syndrome
p.Asn326= Multiple submitters hereditary breast carcinoma
p.Asn380= Multiple submitters hereditary neoplastic syndrome
p.Asn4= Multiple submitters hereditary breast carcinoma
p.Asn419= Multiple submitters hereditary breast carcinoma
p.Asn450= Multiple submitters hereditary neoplastic syndrome
p.Asn470= Multiple submitters hereditary breast carcinoma
p.Asn488= Multiple submitters hereditary neoplastic syndrome
p.Asn524= Multiple submitters hereditary neoplastic syndrome
p.Asn55= Multiple submitters hereditary breast carcinoma
p.Asn626= Multiple submitters hereditary breast carcinoma
p.Asn690= Multiple submitters hereditary breast carcinoma
p.Asn718= Multiple submitters hereditary breast carcinoma
p.Asn73= Multiple submitters hereditary neoplastic syndrome
p.Asn9= Multiple submitters hereditary breast carcinoma
p.Asp126= Multiple submitters hereditary neoplastic syndrome
p.Asp226= Multiple submitters hereditary neoplastic syndrome
p.Asp230= Multiple submitters hereditary neoplastic syndrome
p.Asp290= Multiple submitters hereditary neoplastic syndrome
p.Asp346= Multiple submitters hereditary neoplastic syndrome
p.Asp385= Multiple submitters hereditary breast carcinoma
p.Asp42= Multiple submitters hereditary neoplastic syndrome
p.Asp440= Multiple submitters hereditary neoplastic syndrome
p.Asp500= Multiple submitters hereditary breast carcinoma
p.Asp535= Multiple submitters hereditary neoplastic syndrome
p.Asp567= Multiple submitters hereditary breast carcinoma
p.Asp689= Multiple submitters hereditary neoplastic syndrome
p.Asp710= Multiple submitters hereditary neoplastic syndrome
p.Asp712= Multiple submitters hereditary neoplastic syndrome
p.Asp741= Multiple submitters hereditary neoplastic syndrome
p.Asp765= Multiple submitters hereditary breast carcinoma
p.Asp776= Multiple submitters hereditary neoplastic syndrome
p.Cys243= Multiple submitters hereditary neoplastic syndrome
p.Cys304= Multiple submitters hereditary neoplastic syndrome
p.Cys368= Multiple submitters hereditary breast carcinoma
p.Cys469= Multiple submitters hereditary neoplastic syndrome
p.Cys557Ser Multiple submitters hereditary neoplastic syndrome
p.Cys645= Multiple submitters hereditary neoplastic syndrome
p.Cys645Arg Multiple submitters hereditary neoplastic syndrome
p.Cys74= Multiple submitters hereditary neoplastic syndrome
p.Cys83= Multiple submitters hereditary breast carcinoma
p.Gln100= Multiple submitters hereditary breast carcinoma
p.Gln106= Multiple submitters hereditary breast carcinoma
p.Gln164= Multiple submitters hereditary neoplastic syndrome
p.Gln166= Multiple submitters hereditary neoplastic syndrome
p.Gln177= Multiple submitters hereditary neoplastic syndrome
p.Gln206= Multiple submitters hereditary neoplastic syndrome
p.Gln216= Multiple submitters hereditary neoplastic syndrome
p.Gln253= Multiple submitters BARD1-related cancer predisposition
p.Gln350= Multiple submitters hereditary neoplastic syndrome
p.Gln493= Multiple submitters hereditary neoplastic syndrome
p.Gln564= Multiple submitters hereditary neoplastic syndrome
p.Gln581= Multiple submitters hereditary neoplastic syndrome
p.Gln615= Multiple submitters hereditary breast carcinoma
p.Gln647= Multiple submitters hereditary breast carcinoma
p.Gln715= Multiple submitters hereditary neoplastic syndrome
p.Gln735= Multiple submitters hereditary breast carcinoma
p.Glu119= Multiple submitters hereditary neoplastic syndrome
p.Glu181= Multiple submitters hereditary neoplastic syndrome
p.Glu19= Multiple submitters hereditary neoplastic syndrome
p.Glu223= Multiple submitters hereditary neoplastic syndrome
p.Glu233= Multiple submitters hereditary neoplastic syndrome
p.Glu234= Multiple submitters hereditary neoplastic syndrome
p.Glu284= Multiple submitters hereditary breast carcinoma
p.Glu355= Multiple submitters hereditary neoplastic syndrome
p.Glu361= Multiple submitters hereditary breast carcinoma
p.Glu386= Multiple submitters hereditary neoplastic syndrome
p.Glu445= Multiple submitters hereditary neoplastic syndrome
p.Glu45= Multiple submitters hereditary breast carcinoma
p.Glu478= Multiple submitters hereditary neoplastic syndrome
p.Glu550= Multiple submitters hereditary breast carcinoma
p.Glu580= Multiple submitters hereditary neoplastic syndrome
p.Glu587= Multiple submitters hereditary breast carcinoma
p.Glu59= Multiple submitters hereditary neoplastic syndrome
p.Glu599= Multiple submitters hereditary neoplastic syndrome
p.Glu649= Multiple submitters hereditary breast carcinoma
p.Glu665= Multiple submitters hereditary neoplastic syndrome
p.Glu748= Multiple submitters hereditary neoplastic syndrome
p.Glu771= Multiple submitters hereditary neoplastic syndrome
p.Gly17= Multiple submitters hereditary neoplastic syndrome
p.Gly203= Multiple submitters hereditary neoplastic syndrome
p.Gly323= Multiple submitters hereditary breast carcinoma
p.Gly345= Multiple submitters hereditary neoplastic syndrome
p.Gly377= Multiple submitters hereditary breast carcinoma
p.Gly428= Multiple submitters hereditary neoplastic syndrome
p.Gly451= Multiple submitters hereditary neoplastic syndrome
p.Gly461= Multiple submitters hereditary neoplastic syndrome
p.Gly472= Multiple submitters hereditary neoplastic syndrome
p.Gly517= Multiple submitters hereditary breast carcinoma
p.Gly527= Multiple submitters hereditary neoplastic syndrome
p.Gly563= Multiple submitters hereditary breast carcinoma
p.Gly574= Multiple submitters hereditary breast carcinoma
p.Gly623= Multiple submitters hereditary neoplastic syndrome
p.Gly674= Multiple submitters hereditary breast carcinoma
p.Gly698= Multiple submitters hereditary neoplastic syndrome
p.Gly700= Multiple submitters hereditary neoplastic syndrome
p.Gly753= Multiple submitters hereditary neoplastic syndrome
p.His116= Multiple submitters hereditary neoplastic syndrome
p.His324= Multiple submitters hereditary breast carcinoma
p.His325= Multiple submitters hereditary neoplastic syndrome
p.His36= Multiple submitters hereditary neoplastic syndrome
p.His426= Multiple submitters hereditary neoplastic syndrome
p.His471= Multiple submitters hereditary breast carcinoma
p.His473= Multiple submitters hereditary neoplastic syndrome
p.His499= Multiple submitters hereditary neoplastic syndrome
p.His556= Multiple submitters hereditary breast carcinoma
p.His606= Multiple submitters hereditary neoplastic syndrome
p.His723= Multiple submitters hereditary neoplastic syndrome
p.Ile105= Multiple submitters hereditary neoplastic syndrome
p.Ile14= Multiple submitters hereditary neoplastic syndrome
p.Ile143= Multiple submitters hereditary breast carcinoma
p.Ile169= Multiple submitters hereditary neoplastic syndrome
p.Ile249= Multiple submitters hereditary neoplastic syndrome
p.Ile357= Multiple submitters hereditary neoplastic syndrome
p.Ile437= Multiple submitters hereditary breast carcinoma
p.Ile692= Multiple submitters hereditary breast carcinoma
p.Ile738Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Leu123= Multiple submitters hereditary neoplastic syndrome
p.Leu132= Multiple submitters hereditary breast carcinoma
p.Leu280= Multiple submitters hereditary neoplastic syndrome
p.Leu282= Multiple submitters hereditary neoplastic syndrome
p.Leu316= Multiple submitters hereditary neoplastic syndrome
p.Leu341= Multiple submitters hereditary neoplastic syndrome
p.Leu359= Multiple submitters hereditary breast carcinoma
p.Leu359_Pro365del Multiple submitters hereditary neoplastic syndrome
p.Leu399= Multiple submitters hereditary breast carcinoma
p.Leu41= Multiple submitters hereditary neoplastic syndrome
p.Leu431= Multiple submitters hereditary neoplastic syndrome
p.Leu432= Multiple submitters hereditary breast carcinoma
p.Leu474= Multiple submitters hereditary neoplastic syndrome
p.Leu48= Multiple submitters hereditary breast carcinoma
p.Leu480= Multiple submitters hereditary neoplastic syndrome
p.Leu481= Multiple submitters hereditary neoplastic syndrome
p.Leu512= Multiple submitters hereditary breast carcinoma
p.Leu528= Multiple submitters hereditary breast carcinoma
p.Leu542= Multiple submitters hereditary neoplastic syndrome
p.Leu543= Multiple submitters hereditary neoplastic syndrome
p.Leu545= Multiple submitters hereditary neoplastic syndrome
p.Leu57= Multiple submitters hereditary breast carcinoma
p.Leu572= Multiple submitters hereditary neoplastic syndrome
p.Leu577= Multiple submitters hereditary neoplastic syndrome
p.Leu585= Multiple submitters hereditary neoplastic syndrome
p.Leu622= Multiple submitters hereditary neoplastic syndrome
p.Leu625= Multiple submitters hereditary breast carcinoma
p.Leu63= Multiple submitters hereditary breast carcinoma
p.Leu640= Multiple submitters hereditary neoplastic syndrome
p.Leu662= Multiple submitters hereditary neoplastic syndrome
p.Leu671= Multiple submitters hereditary neoplastic syndrome
p.Leu703= Multiple submitters hereditary neoplastic syndrome
p.Leu775= Multiple submitters hereditary neoplastic syndrome
p.Lys124= Multiple submitters hereditary neoplastic syndrome
p.Lys130= Multiple submitters hereditary breast carcinoma
p.Lys140= Multiple submitters hereditary neoplastic syndrome
p.Lys152= Multiple submitters hereditary neoplastic syndrome
p.Lys153= Multiple submitters hereditary neoplastic syndrome
p.Lys171= Multiple submitters hereditary breast carcinoma
p.Lys197= Multiple submitters hereditary breast carcinoma
p.Lys205= Multiple submitters hereditary neoplastic syndrome
p.Lys207Arg Multiple submitters Breast and/or ovarian cancer
p.Lys209= Multiple submitters hereditary neoplastic syndrome
p.Lys217= Multiple submitters hereditary neoplastic syndrome
p.Lys224= Multiple submitters hereditary neoplastic syndrome
p.Lys232= Multiple submitters hereditary breast carcinoma
p.Lys236= Multiple submitters hereditary neoplastic syndrome
p.Lys292= Multiple submitters hereditary neoplastic syndrome
p.Lys302= Multiple submitters hereditary neoplastic syndrome
p.Lys423= Multiple submitters hereditary neoplastic syndrome
p.Lys475= Multiple submitters hereditary neoplastic syndrome
p.Lys484= Multiple submitters hereditary breast carcinoma
p.Lys511= Multiple submitters hereditary neoplastic syndrome
p.Lys596= Multiple submitters BARD1-related cancer predisposition
p.Lys650= Multiple submitters hereditary neoplastic syndrome
p.Lys708= Multiple submitters hereditary breast carcinoma
p.Lys754= Multiple submitters hereditary neoplastic syndrome
p.Lys96= Multiple submitters hereditary breast carcinoma
p.Phe229= Multiple submitters hereditary neoplastic syndrome
p.Phe387= Multiple submitters hereditary breast carcinoma
p.Phe672= Multiple submitters hereditary breast carcinoma
p.Phe677= Multiple submitters hereditary neoplastic syndrome
p.Pro12= Multiple submitters hereditary neoplastic syndrome
p.Pro128= Multiple submitters hereditary breast carcinoma
p.Pro188= Multiple submitters hereditary breast carcinoma
p.Pro2= Multiple submitters hereditary breast carcinoma
p.Pro24= Multiple submitters hereditary breast carcinoma
p.Pro246= Multiple submitters BARD1-related cancer predisposition
p.Pro28= Multiple submitters hereditary breast carcinoma
p.Pro300= Multiple submitters hereditary neoplastic syndrome
p.Pro315= Multiple submitters hereditary neoplastic syndrome
p.Pro353= Multiple submitters hereditary neoplastic syndrome
p.Pro358= Multiple submitters hereditary neoplastic syndrome
p.Pro360= Multiple submitters hereditary breast ovarian cancer syndrome
p.Pro392= Multiple submitters hereditary breast carcinoma
p.Pro411= Multiple submitters hereditary neoplastic syndrome
p.Pro464= Multiple submitters hereditary neoplastic syndrome
p.Pro497= Multiple submitters hereditary neoplastic syndrome
p.Pro546= Multiple submitters hereditary breast carcinoma
p.Pro669= Multiple submitters hereditary neoplastic syndrome
p.Pro687= Multiple submitters hereditary neoplastic syndrome
p.Pro709= Multiple submitters hereditary neoplastic syndrome
p.Pro726= Multiple submitters hereditary breast carcinoma
p.Pro747= Multiple submitters hereditary neoplastic syndrome
p.Pro759= Multiple submitters hereditary neoplastic syndrome
p.Pro774= Multiple submitters BARD1-related cancer predisposition
p.Ser131= Multiple submitters hereditary neoplastic syndrome
p.Ser174= Multiple submitters hereditary neoplastic syndrome
p.Ser179= Multiple submitters hereditary neoplastic syndrome
p.Ser202= Multiple submitters hereditary neoplastic syndrome
p.Ser231= Multiple submitters hereditary neoplastic syndrome
p.Ser241= Multiple submitters hereditary breast carcinoma
p.Ser241Cys Multiple submitters hereditary neoplastic syndrome ⚠
p.Ser244= Multiple submitters hereditary breast carcinoma
p.Ser263= Multiple submitters hereditary neoplastic syndrome
p.Ser269= Multiple submitters hereditary neoplastic syndrome
p.Ser279= Multiple submitters hereditary neoplastic syndrome
p.Ser288= Multiple submitters hereditary neoplastic syndrome
p.Ser313= Multiple submitters hereditary neoplastic syndrome
p.Ser329= Multiple submitters hereditary neoplastic syndrome
p.Ser339= Multiple submitters hereditary neoplastic syndrome
p.Ser342= Multiple submitters hereditary neoplastic syndrome
p.Ser367= Multiple submitters hereditary neoplastic syndrome
p.Ser376= Multiple submitters hereditary neoplastic syndrome
p.Ser400= Multiple submitters hereditary neoplastic syndrome

Likely benign 647

Showing the top 300 by review status; the full set is in the sitemap.

c.1314+13C>T Multiple submitters hereditary neoplastic syndrome
c.1314+15C>G Multiple submitters hereditary neoplastic syndrome
c.1314+8G>T Multiple submitters hereditary breast carcinoma
c.1315-10A>C Multiple submitters hereditary neoplastic syndrome
c.1315-10A>G Multiple submitters hereditary breast carcinoma
c.1315-10A>T Multiple submitters hereditary neoplastic syndrome
c.1315-11C>T Multiple submitters hereditary breast carcinoma
c.1315-11del Multiple submitters hereditary breast carcinoma
c.1315-14_1315-12del Multiple submitters hereditary neoplastic syndrome
c.1315-14G>A Multiple submitters hereditary breast carcinoma
c.1315-14G>T Multiple submitters hereditary neoplastic syndrome
c.1315-16T>A Multiple submitters hereditary neoplastic syndrome
c.1315-20_1315-19delinsTA Multiple submitters hereditary breast carcinoma
c.1315-20C>T Multiple submitters hereditary breast carcinoma
c.1315-4C>G Multiple submitters hereditary neoplastic syndrome
c.1315-5T>C Multiple submitters hereditary breast carcinoma
c.1315-8T>C Multiple submitters hereditary breast carcinoma
c.1395+14T>G Multiple submitters hereditary neoplastic syndrome
c.1395+7G>A Multiple submitters hereditary breast carcinoma
c.1395+8T>A Multiple submitters hereditary breast carcinoma
c.1396-10A>T Multiple submitters hereditary neoplastic syndrome
c.1396-16C>T Multiple submitters hereditary breast carcinoma
c.1396-18T>G Multiple submitters hereditary neoplastic syndrome
c.1396-22del Multiple submitters hereditary breast ovarian cancer syndrome
c.1568+10T>A Multiple submitters hereditary breast carcinoma
c.1568+111A>C Multiple submitters
c.1568+11C>G Multiple submitters hereditary breast carcinoma
c.1568+13A>G Multiple submitters hereditary neoplastic syndrome
c.1568+15G>A Multiple submitters hereditary neoplastic syndrome
c.1568+20A>C Multiple submitters hereditary neoplastic syndrome
c.1568+7A>G Multiple submitters hereditary breast carcinoma
c.1569-12T>C Multiple submitters hereditary breast carcinoma
c.1569-13C>T Multiple submitters hereditary breast carcinoma
c.1569-14A>G Multiple submitters hereditary neoplastic syndrome
c.1569-15C>T Multiple submitters hereditary neoplastic syndrome
c.1569-16G>A Multiple submitters hereditary neoplastic syndrome
c.1569-18C>T Multiple submitters hereditary neoplastic syndrome
c.1569-20A>G Multiple submitters hereditary neoplastic syndrome
c.1569-20A>T Multiple submitters hereditary breast carcinoma
c.1569-5A>G Multiple submitters hereditary breast carcinoma
c.1569-9T>C Multiple submitters hereditary breast carcinoma
c.158+19G>T Multiple submitters hereditary breast carcinoma
c.158+20G>A Multiple submitters hereditary neoplastic syndrome
c.158+20G>C Multiple submitters hereditary neoplastic syndrome
c.158+20G>T Multiple submitters hereditary neoplastic syndrome
c.158+41G>T Multiple submitters
c.158+9G>A Multiple submitters hereditary neoplastic syndrome
c.158+9G>T Multiple submitters hereditary neoplastic syndrome
c.159-10C>T Multiple submitters hereditary breast carcinoma
c.159-15A>C Multiple submitters hereditary breast carcinoma
c.159-17T>C Multiple submitters hereditary breast carcinoma
c.159-20G>A Multiple submitters hereditary breast carcinoma
c.159-6A>G Multiple submitters hereditary breast carcinoma
c.1677+10G>A Multiple submitters hereditary breast carcinoma
c.1677+17C>T Multiple submitters hereditary breast carcinoma
c.1677+7A>G Multiple submitters hereditary breast carcinoma
c.1678-10A>T Multiple submitters hereditary breast carcinoma
c.1678-11T>G Multiple submitters hereditary neoplastic syndrome
c.1678-12T>C Multiple submitters hereditary neoplastic syndrome
c.1678-12T>G Multiple submitters hereditary breast carcinoma
c.1678-17T>G Multiple submitters hereditary neoplastic syndrome
c.1678-60T>C Multiple submitters hereditary breast ovarian cancer syndrome
c.1678-8A>G Multiple submitters hereditary breast carcinoma
c.1810+12G>A Multiple submitters hereditary breast carcinoma
c.1810+6G>T Multiple submitters hereditary breast carcinoma
c.1811-16T>C Multiple submitters hereditary neoplastic syndrome
c.1811-17C>T Multiple submitters hereditary breast carcinoma
c.1811-18G>C Multiple submitters hereditary breast carcinoma
c.1811-20C>T Multiple submitters hereditary breast carcinoma
c.1811-7A>G Multiple submitters hereditary neoplastic syndrome
c.1811-9G>A Multiple submitters hereditary breast carcinoma
c.1903+10G>C Multiple submitters hereditary breast carcinoma
c.1903+145G>A Multiple submitters
c.1903+17A>G Multiple submitters hereditary neoplastic syndrome
c.1903+8T>A Multiple submitters hereditary breast carcinoma
c.1903+9T>C Multiple submitters hereditary breast carcinoma
c.1904-11G>C Multiple submitters hereditary breast carcinoma
c.1904-15T>C Multiple submitters hereditary breast carcinoma
c.1904-67A>G Multiple submitters hereditary breast ovarian cancer syndrome
c.1904-6T>C Multiple submitters hereditary breast carcinoma
c.2001+18C>T Multiple submitters hereditary breast carcinoma
c.2001+224C>T Multiple submitters
c.2001+9C>G Multiple submitters hereditary breast carcinoma
c.2002-10A>C Multiple submitters hereditary breast carcinoma
c.2002-10A>G Multiple submitters hereditary neoplastic syndrome
c.2002-15T>C Multiple submitters hereditary neoplastic syndrome
c.2002-17T>C Multiple submitters hereditary breast carcinoma
c.2002-18G>A Multiple submitters hereditary breast carcinoma
c.2002-9T>C Multiple submitters hereditary breast carcinoma
c.215+14G>A Multiple submitters hereditary neoplastic syndrome
c.215+20T>A Multiple submitters hereditary neoplastic syndrome
c.215+59_215+60del Multiple submitters hereditary breast ovarian cancer syndrome
c.215+7A>C Multiple submitters hereditary breast carcinoma
c.215+8A>G Multiple submitters hereditary breast carcinoma
c.216-10_216-5del Multiple submitters hereditary breast carcinoma
c.216-11T>C Multiple submitters hereditary breast carcinoma
c.216-12A>C Multiple submitters hereditary neoplastic syndrome
c.216-13A>T Multiple submitters hereditary breast carcinoma
c.216-13dup Multiple submitters hereditary neoplastic syndrome
c.216-14T>A Multiple submitters hereditary neoplastic syndrome
c.216-16_216-14del Multiple submitters hereditary neoplastic syndrome
c.216-19_216-18insG Multiple submitters hereditary breast carcinoma
c.216-4A>T Multiple submitters hereditary neoplastic syndrome
c.364+10A>G Multiple submitters hereditary breast carcinoma
c.364+11T>C Multiple submitters hereditary breast carcinoma
c.364+13_364+18del Multiple submitters hereditary breast carcinoma
c.364+14C>G Multiple submitters hereditary neoplastic syndrome
c.364+17T>A Multiple submitters hereditary breast carcinoma
c.364+8C>A Multiple submitters hereditary breast carcinoma
c.364+8C>T Multiple submitters hereditary breast carcinoma
c.364+9T>C Multiple submitters hereditary neoplastic syndrome
c.365-16T>G Multiple submitters hereditary neoplastic syndrome
c.365-17T>C Multiple submitters hereditary breast carcinoma
c.365-4T>C Multiple submitters hereditary neoplastic syndrome
c.365-8T>A Multiple submitters hereditary breast carcinoma
c.365-9T>C Multiple submitters hereditary neoplastic syndrome
p.Arg10= Multiple submitters hereditary breast carcinoma
p.Arg15Leu Multiple submitters hereditary breast carcinoma
p.Arg49= Multiple submitters hereditary neoplastic syndrome
p.Arg725= Multiple submitters hereditary breast carcinoma
p.Asn98= Multiple submitters hereditary breast carcinoma
p.Asp102= Multiple submitters hereditary neoplastic syndrome
p.Asp117= Multiple submitters hereditary breast carcinoma
p.Asp135= Multiple submitters hereditary neoplastic syndrome
p.Asp458= Multiple submitters hereditary neoplastic syndrome
p.Asp532= Multiple submitters hereditary neoplastic syndrome
p.Asp536= Multiple submitters hereditary breast carcinoma
p.Cys336= Multiple submitters hereditary breast carcinoma
p.Cys362= Multiple submitters hereditary neoplastic syndrome
p.Gln582= Multiple submitters hereditary breast carcinoma
p.Glu268= Multiple submitters hereditary neoplastic syndrome
p.Glu27= Multiple submitters hereditary breast carcinoma
p.Glu277= Multiple submitters hereditary neoplastic syndrome
p.Glu646= Multiple submitters hereditary neoplastic syndrome
p.Glu648= Multiple submitters Breast and/or ovarian cancer
p.Gly273= Multiple submitters hereditary neoplastic syndrome
p.Gly505= Multiple submitters hereditary neoplastic syndrome
p.Gly568= Multiple submitters hereditary neoplastic syndrome
p.Gly82= Multiple submitters hereditary neoplastic syndrome
p.His466= Multiple submitters hereditary neoplastic syndrome
p.Ile214= Multiple submitters hereditary neoplastic syndrome
p.Ile573= Multiple submitters hereditary neoplastic syndrome
p.Ile653= Multiple submitters hereditary neoplastic syndrome
p.Ile69= Multiple submitters hereditary neoplastic syndrome
p.Ile702= Multiple submitters hereditary neoplastic syndrome
p.Ile79= Multiple submitters hereditary neoplastic syndrome
p.Leu111= Multiple submitters hereditary neoplastic syndrome
p.Leu120= Multiple submitters hereditary neoplastic syndrome
p.Leu239= Multiple submitters hereditary neoplastic syndrome
p.Leu275= Multiple submitters hereditary breast carcinoma
p.Leu448= Multiple submitters hereditary neoplastic syndrome
p.Leu479= Multiple submitters hereditary neoplastic syndrome
p.Leu544= Multiple submitters hereditary neoplastic syndrome
p.Leu570= Multiple submitters hereditary breast carcinoma
p.Leu618= Multiple submitters hereditary breast carcinoma
p.Leu679= Multiple submitters hereditary breast carcinoma
p.Leu773= Multiple submitters hereditary neoplastic syndrome
p.Lys110= Multiple submitters hereditary neoplastic syndrome
p.Lys207= Multiple submitters hereditary neoplastic syndrome
p.Lys312= Multiple submitters hereditary neoplastic syndrome
p.Lys379= Multiple submitters hereditary breast carcinoma
p.Lys540= Multiple submitters hereditary neoplastic syndrome
p.Lys593= Multiple submitters hereditary neoplastic syndrome
p.Lys595= Multiple submitters hereditary neoplastic syndrome
p.Lys693= Multiple submitters hereditary neoplastic syndrome
p.Lys706= Multiple submitters hereditary neoplastic syndrome
p.Lys757= Multiple submitters hereditary breast carcinoma
p.Pro167= Multiple submitters hereditary neoplastic syndrome
p.Pro185= Multiple submitters hereditary breast carcinoma
p.Pro395= Multiple submitters hereditary neoplastic syndrome
p.Pro418= Multiple submitters hereditary neoplastic syndrome
p.Pro84= Multiple submitters hereditary neoplastic syndrome
p.Ser51= Multiple submitters hereditary breast carcinoma
p.Ser541= Multiple submitters hereditary neoplastic syndrome
p.Ser602= Multiple submitters hereditary neoplastic syndrome
p.Thr716= Multiple submitters hereditary breast carcinoma
p.Val154= Multiple submitters hereditary neoplastic syndrome
p.Val248= Multiple submitters hereditary neoplastic syndrome
p.Val278= Multiple submitters hereditary neoplastic syndrome
p.Val348= Multiple submitters hereditary neoplastic syndrome
p.Val372= Multiple submitters hereditary neoplastic syndrome
p.Val510= Multiple submitters hereditary neoplastic syndrome
p.Val713= Multiple submitters hereditary neoplastic syndrome
c.1314+10T>A Single submitter hereditary breast carcinoma
c.1314+10T>C Single submitter hereditary neoplastic syndrome
c.1314+12A>G Single submitter hereditary breast carcinoma
c.1314+13C>A Single submitter hereditary breast carcinoma
c.1314+16T>C Single submitter hereditary breast carcinoma
c.1314+16T>G Single submitter hereditary breast carcinoma
c.1314+19A>G Single submitter hereditary breast carcinoma
c.1314+6A>G Single submitter hereditary breast carcinoma
c.1314+7T>A Single submitter hereditary breast carcinoma
c.1314+7T>G Single submitter hereditary breast carcinoma
c.1314+99_1314+106del Single submitter
c.1314+9C>A Single submitter hereditary breast carcinoma
c.1314+9C>G Single submitter hereditary breast carcinoma
c.1314+9C>T Single submitter hereditary breast carcinoma
c.1315-15T>C Single submitter hereditary breast carcinoma
c.1315-17T>G Single submitter hereditary breast carcinoma
c.1315-18T>C Single submitter hereditary breast carcinoma
c.1315-23_1315-19delinsCTCCA Single submitter hereditary breast carcinoma
c.1315-26A>G Single submitter
c.1315-285G>A Single submitter
c.1315-7T>C Single submitter hereditary breast carcinoma
c.1395+10T>A Single submitter hereditary breast carcinoma
c.1395+11G>C Single submitter hereditary breast carcinoma
c.1395+12G>C Single submitter hereditary breast carcinoma
c.1395+13T>A Single submitter hereditary breast carcinoma
c.1395+13T>G Single submitter hereditary breast carcinoma
c.1395+15T>C Single submitter hereditary breast carcinoma
c.1395+18A>G Single submitter hereditary breast carcinoma
c.1395+18del Single submitter hereditary breast carcinoma
c.1395+29T>C Single submitter
c.1395+43G>A Single submitter
c.1395+50T>C Single submitter
c.1395+7G>T Single submitter hereditary breast carcinoma
c.1395+8T>C Single submitter hereditary breast carcinoma
c.1395+9C>G Single submitter hereditary breast carcinoma
c.1396-10A>C Single submitter hereditary breast carcinoma
c.1396-11A>C Single submitter hereditary breast carcinoma
c.1396-11A>T Single submitter hereditary breast carcinoma
c.1396-13A>C Single submitter hereditary neoplastic syndrome
c.1396-14A>C Single submitter hereditary breast carcinoma
c.1396-279G>C Single submitter
c.1396-6A>G Single submitter hereditary breast carcinoma
c.1396-7T>A Single submitter hereditary breast carcinoma
c.1396-8T>A Single submitter hereditary breast carcinoma
c.1568+12A>G Single submitter hereditary breast carcinoma
c.1568+13_1568+14inv Single submitter hereditary breast carcinoma
c.1568+14_1568+15delinsTT Single submitter hereditary neoplastic syndrome
c.1568+14C>A Single submitter hereditary breast carcinoma
c.1568+15G>C Single submitter hereditary breast carcinoma
c.1568+39C>G Single submitter
c.1568+8G>A Single submitter hereditary breast carcinoma
c.1568+8G>T Single submitter hereditary breast carcinoma
c.1568+9T>G Single submitter hereditary breast carcinoma
c.1569-11del Single submitter hereditary breast carcinoma
c.1569-184G>A Single submitter
c.1569-42C>T Single submitter
c.1569-6T>C Single submitter hereditary breast carcinoma
c.1569-7T>C Single submitter hereditary breast carcinoma
c.1569-87T>G Single submitter hereditary breast ovarian cancer syndrome
c.158+10G>C Single submitter hereditary breast carcinoma
c.158+12G>A Single submitter hereditary breast carcinoma
c.158+13C>G Single submitter hereditary breast carcinoma
c.158+13C>T Single submitter hereditary breast carcinoma
c.158+13del Single submitter
c.158+15T>C Single submitter hereditary breast carcinoma
c.158+15T>G Single submitter hereditary breast carcinoma
c.158+16C>T Single submitter hereditary breast carcinoma
c.158+17T>C Single submitter hereditary breast carcinoma
c.158+17T>G Single submitter hereditary breast carcinoma
c.158+188G>T Single submitter
c.158+19G>A Single submitter hereditary breast carcinoma
c.158+19G>C Single submitter hereditary breast carcinoma
c.158+9G>C Single submitter hereditary breast carcinoma
c.159-10C>A Single submitter hereditary breast carcinoma
c.159-13T>C Single submitter hereditary breast carcinoma
c.159-14A>T Single submitter hereditary breast carcinoma
c.159-15A>G Single submitter hereditary breast carcinoma
c.159-15A>T Single submitter hereditary breast carcinoma
c.159-16del Single submitter hereditary breast carcinoma
c.159-16T>G Single submitter hereditary breast carcinoma
c.159-20G>T Single submitter hereditary breast carcinoma
c.159-23_159-20del Single submitter hereditary breast carcinoma
c.159-261T>G Single submitter
c.159-3_159-2insTTTAATTTCTTCAAACTGTTAGTACTG Single submitter hereditary breast carcinoma
c.159-65T>C Single submitter hereditary breast ovarian cancer syndrome
c.159-6A>C Single submitter hereditary breast carcinoma
c.159-9T>C Single submitter hereditary breast carcinoma
c.1677+11A>G Single submitter hereditary breast carcinoma
c.1677+11A>T Single submitter hereditary breast carcinoma
c.1677+16G>C Single submitter hereditary breast carcinoma
c.1677+19T>G Single submitter hereditary breast carcinoma
c.1677+206T>C Single submitter
c.1677+20del Single submitter hereditary breast carcinoma
c.1677+7A>C Single submitter hereditary breast carcinoma
c.1677+9G>A Single submitter hereditary breast carcinoma
c.1678-10A>G Single submitter hereditary breast carcinoma
c.1678-11del Single submitter hereditary breast carcinoma
c.1678-11T>A Single submitter hereditary breast carcinoma
c.1678-11T>C Single submitter hereditary breast carcinoma
c.1678-14T>C Single submitter hereditary breast carcinoma
c.1678-18C>T Single submitter hereditary breast carcinoma
c.1678-42G>A Single submitter
c.1678-44T>C Single submitter
c.1678-6T>C Single submitter hereditary breast carcinoma
c.1678-8A>T Single submitter hereditary breast carcinoma
c.1678-9T>C Single submitter hereditary breast carcinoma
c.1810+14A>G Single submitter hereditary breast carcinoma
c.1810+17T>C Single submitter hereditary breast carcinoma
c.1810+18T>G Single submitter hereditary breast carcinoma
c.1810+19G>A Single submitter hereditary breast carcinoma
c.1810+19G>T Single submitter hereditary breast carcinoma
c.1810+49A>G Single submitter
c.1810+8T>G Single submitter hereditary breast carcinoma
c.1811-11T>C Single submitter hereditary breast carcinoma
c.1811-13T>C Single submitter hereditary breast carcinoma
c.1811-15T>A Single submitter hereditary breast carcinoma
c.1811-15T>C Single submitter hereditary breast carcinoma

Uncertain significance 2037

Showing the top 300 by review status; the full set is in the sitemap.

c.1314+5del Multiple submitters hereditary neoplastic syndrome
c.1314+5G>A Multiple submitters hereditary neoplastic syndrome
c.1314+5G>T Multiple submitters hereditary neoplastic syndrome
c.1315-2A>T Multiple submitters hereditary neoplastic syndrome
c.1395+14T>A Multiple submitters hereditary neoplastic syndrome
c.1395+1G>C Multiple submitters hereditary neoplastic syndrome
c.1395+3A>G Multiple submitters hereditary neoplastic syndrome
c.1396-3T>G Multiple submitters hereditary neoplastic syndrome
c.1396-4T>G Multiple submitters hereditary neoplastic syndrome
c.1568+6T>A Multiple submitters Breast and/or ovarian cancer
c.1569-3C>G Multiple submitters hereditary neoplastic syndrome
c.1569-3C>T Multiple submitters hereditary neoplastic syndrome
c.159-3C>T Multiple submitters hereditary breast carcinoma
c.159-5A>G Multiple submitters hereditary neoplastic syndrome
c.1677+4_1677+7del Multiple submitters BARD1-related cancer predisposition
c.1677+4A>C Multiple submitters hereditary breast carcinoma
c.1677+5G>C Multiple submitters hereditary neoplastic syndrome
c.1677+6T>C Multiple submitters hereditary breast carcinoma
c.1678-3C>T Multiple submitters hereditary neoplastic syndrome
c.1810+5G>A Multiple submitters hereditary neoplastic syndrome
c.1903+2dup Multiple submitters hereditary breast carcinoma
c.1903+4A>T Multiple submitters hereditary breast carcinoma
c.1903+5_1903+6insGCTGGATTCTAAAATTTGAATGTAAGG Multiple submitters hereditary neoplastic syndrome
c.2001+6T>C Multiple submitters hereditary neoplastic syndrome
c.2002-3C>T Multiple submitters hereditary breast carcinoma
c.2002-6T>G Multiple submitters hereditary breast carcinoma
c.215+3A>G Multiple submitters hereditary neoplastic syndrome
c.215+4A>G Multiple submitters hereditary breast carcinoma
c.364+3A>G Multiple submitters hereditary neoplastic syndrome
c.365-3C>G Multiple submitters hereditary neoplastic syndrome
c.-2C>G Multiple submitters hereditary neoplastic syndrome
p.4_8NRQPR[3] Multiple submitters hereditary neoplastic syndrome
p.Ala136Ser Multiple submitters hereditary breast carcinoma ⚠
p.Ala136Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala173Gly Multiple submitters hereditary breast carcinoma ⚠
p.Ala175Thr Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala195Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala198Pro Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala198Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala200Val Multiple submitters hereditary breast carcinoma ⚠
p.Ala212Gly Multiple submitters hereditary breast carcinoma ⚠
p.Ala212Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala23Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala25Val Multiple submitters hereditary breast carcinoma ⚠
p.Ala262Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala283Pro Multiple submitters hereditary breast carcinoma ⚠
p.Ala283Thr Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala283Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala33Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala33Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala35Asp Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala35Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala35Thr Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala35Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala39Thr Multiple submitters hereditary breast carcinoma ⚠
p.Ala39Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala40Thr Multiple submitters hereditary breast carcinoma ⚠
p.Ala421Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala421Thr Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala435Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala435Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala435Val Multiple submitters hereditary breast carcinoma ⚠
p.Ala460Thr Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala460Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala468Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala468Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala468Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala485Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala485Val Multiple submitters hereditary breast carcinoma ⚠
p.Ala518Asp Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala518Thr Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala518Val Multiple submitters hereditary breast carcinoma ⚠
p.Ala522Ser Multiple submitters hereditary breast carcinoma ⚠
p.Ala522Thr Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala554Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala589Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala589Thr Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala589Val Multiple submitters hereditary breast carcinoma ⚠
p.Ala594Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala594Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala613Gly Multiple submitters hereditary breast carcinoma ⚠
p.Ala638Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala721Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala721Thr Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala721Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala724Glu Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala724Gly Multiple submitters hereditary breast carcinoma ⚠
p.Ala724Thr Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala724Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala758Pro Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala758Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala758Thr Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala758Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Ala90Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg10Pro Multiple submitters hereditary breast carcinoma ⚠
p.Arg112Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg112Pro Multiple submitters hereditary breast carcinoma ⚠
p.Arg129Gly Multiple submitters hereditary breast carcinoma ⚠
p.Arg13Lys Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg13Thr Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg150Gln Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg150Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg150Leu Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg150Pro Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg155Lys Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg15Cys Multiple submitters hereditary breast carcinoma ⚠
p.Arg15His Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg15Ser Multiple submitters hereditary breast carcinoma ⚠
p.Arg194Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg194Trp Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg201Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg201Ile Multiple submitters hereditary breast carcinoma ⚠
p.Arg21Cys Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg21Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg21Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg294Gly Multiple submitters hereditary breast carcinoma ⚠
p.Arg31Cys Multiple submitters hereditary breast carcinoma ⚠
p.Arg31Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg322Cys Multiple submitters BARD1-related cancer predisposition ⚠
p.Arg322Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg335Lys Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg337Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg378_Lys379delinsSerThr Multiple submitters hereditary neoplastic syndrome
p.Arg38Cys Multiple submitters hereditary breast ovarian cancer syndrome ⚠
p.Arg38Gly Multiple submitters hereditary breast carcinoma ⚠
p.Arg38His Multiple submitters hereditary breast carcinoma ⚠
p.Arg38Pro Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg38Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg405Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg405Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg424Gly Multiple submitters hereditary breast carcinoma ⚠
p.Arg424Ser Multiple submitters hereditary breast carcinoma ⚠
p.Arg427del Multiple submitters hereditary neoplastic syndrome
p.Arg427Gly Multiple submitters hereditary breast carcinoma ⚠
p.Arg427Ile Multiple submitters hereditary breast carcinoma ⚠
p.Arg427Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg43Cys Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg43Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg43His Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg43Leu Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg43Pro Multiple submitters hereditary breast ovarian cancer syndrome ⚠
p.Arg43Ser Multiple submitters BARD1-related disorder ⚠
p.Arg49Cys Multiple submitters hereditary breast carcinoma ⚠
p.Arg529Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg52His Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg52Pro Multiple submitters hereditary breast carcinoma ⚠
p.Arg52Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg565Cys Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg565Leu Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg566Lys Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg5Pro Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg5Trp Multiple submitters hereditary breast carcinoma ⚠
p.Arg641Gly Multiple submitters hereditary breast carcinoma ⚠
p.Arg642Lys Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg658Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg658Pro Multiple submitters hereditary breast carcinoma ⚠
p.Arg659Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg659Lys Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg659Thr Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg661Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg661Ser Multiple submitters BARD1-related cancer predisposition ⚠
p.Arg664Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg664Lys Multiple submitters hereditary breast carcinoma ⚠
p.Arg705Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg705Lys Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg725Ile Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg725Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg725Thr Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg749Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg749Thr Multiple submitters BARD1-related disorder ⚠
p.Arg751Gln Multiple submitters Breast and/or ovarian cancer ⚠
p.Arg751Pro Multiple submitters hereditary breast carcinoma ⚠
p.Arg751Trp Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg8Lys Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg8Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg8Thr Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg99Lys Multiple submitters hereditary neoplastic syndrome ⚠
p.Arg99Thr Multiple submitters hereditary breast carcinoma ⚠
p.Asn134Ser Multiple submitters hereditary breast carcinoma ⚠
p.Asn141Ser Multiple submitters hereditary breast carcinoma ⚠
p.Asn18Asp Multiple submitters hereditary breast carcinoma ⚠
p.Asn18Ser Multiple submitters hereditary breast carcinoma ⚠
p.Asn215Ile Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn215Tyr Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn219Lys Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn255Asp Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn255Thr Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn326His Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn326Tyr Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn356Tyr Multiple submitters hereditary breast carcinoma ⚠
p.Asn380Asp Multiple submitters hereditary breast carcinoma ⚠
p.Asn382Asp Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn425Lys Multiple submitters hereditary breast carcinoma ⚠
p.Asn425Ser Multiple submitters hereditary breast carcinoma ⚠
p.Asn455Asp Multiple submitters hereditary breast carcinoma ⚠
p.Asn488Asp Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn488Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn494Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn524His Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn524Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn549Ser Multiple submitters hereditary breast carcinoma ⚠
p.Asn55Tyr Multiple submitters hereditary breast carcinoma ⚠
p.Asn561Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn663Lys Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn663Ser Multiple submitters hereditary breast carcinoma ⚠
p.Asn690Lys Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn744Asp Multiple submitters hereditary breast carcinoma ⚠
p.Asn744Lys Multiple submitters hereditary breast carcinoma ⚠
p.Asn98Asp Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn98His Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn98Lys Multiple submitters hereditary neoplastic syndrome ⚠
p.Asn98Thr Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp102Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp102Val Multiple submitters hereditary breast carcinoma ⚠
p.Asp117Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp122Val Multiple submitters hereditary breast carcinoma ⚠
p.Asp126Asn Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp126Tyr Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp135Asn Multiple submitters hereditary breast carcinoma ⚠
p.Asp135Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp135Phe Multiple submitters hereditary neoplastic syndrome
p.Asp172Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp178Asn Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp190Glu Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp190Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp190Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp230Asn Multiple submitters hereditary breast carcinoma ⚠
p.Asp230Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp230Tyr Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp259Asn Multiple submitters hereditary breast carcinoma ⚠
p.Asp259Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp290Gly Multiple submitters hereditary breast carcinoma ⚠
p.Asp29Asn Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp346Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp346Tyr Multiple submitters hereditary breast carcinoma ⚠
p.Asp346Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp385Tyr Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp3Asn Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp3Tyr Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp42His Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp42Tyr Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp440Asn Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp440Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp440Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp458Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp458His Multiple submitters hereditary breast carcinoma ⚠
p.Asp495Asn Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp495Glu Multiple submitters hereditary breast carcinoma ⚠
p.Asp500Asn Multiple submitters BARD1-related cancer predisposition ⚠
p.Asp500Glu Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp500His Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp500Tyr Multiple submitters BARD1-related cancer predisposition ⚠
p.Asp500Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp508Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp508Val Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp532Asn Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp532Gly Multiple submitters hereditary breast carcinoma ⚠
p.Asp535Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp536Asn Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp536His Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp601Asn Multiple submitters BARD1-related cancer predisposition ⚠
p.Asp673Gly Multiple submitters hereditary breast carcinoma ⚠
p.Asp673Tyr Multiple submitters hereditary breast carcinoma ⚠
p.Asp689Asn Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp689Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp712Asn Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp712Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp727Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp727His Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp729Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp729His Multiple submitters hereditary breast carcinoma ⚠
p.Asp729Tyr Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp729Val Multiple submitters hereditary breast carcinoma ⚠
p.Asp741Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp741His Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp741Tyr Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp765Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Asp94Ala Multiple submitters hereditary breast carcinoma ⚠
p.Cys108Arg Multiple submitters hereditary neoplastic syndrome ⚠
p.Cys108Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Cys243Phe Multiple submitters hereditary neoplastic syndrome ⚠
p.Cys243Tyr Multiple submitters hereditary breast carcinoma ⚠
p.Cys336Arg Multiple submitters hereditary neoplastic syndrome ⚠
p.Cys336Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Cys469Gly Multiple submitters hereditary neoplastic syndrome ⚠
p.Cys469Tyr Multiple submitters hereditary neoplastic syndrome ⚠
p.Cys50Tyr Multiple submitters hereditary breast carcinoma ⚠
p.Cys53Gly Multiple submitters Breast and/or ovarian cancer ⚠
p.Cys620Arg Multiple submitters hereditary neoplastic syndrome ⚠
p.Cys620Gly Multiple submitters hereditary breast carcinoma ⚠
p.Cys620Tyr Multiple submitters hereditary neoplastic syndrome ⚠
p.Cys628Arg Multiple submitters hereditary neoplastic syndrome ⚠
p.Cys628Phe Multiple submitters hereditary breast carcinoma ⚠
p.Cys628Ser Multiple submitters hereditary breast carcinoma ⚠
p.Cys628Tyr Multiple submitters hereditary neoplastic syndrome ⚠
p.Cys62Arg Multiple submitters hereditary neoplastic syndrome ⚠
p.Cys62Phe Multiple submitters hereditary neoplastic syndrome ⚠
p.Cys62Ser Multiple submitters hereditary neoplastic syndrome ⚠
p.Cys639Arg Multiple submitters hereditary neoplastic syndrome ⚠
p.Cys639Gly Multiple submitters hereditary breast carcinoma ⚠